Pathology
Zahra Shahi; Mohammad Amin Edalatmanesh; Babak kheirkhah
Volume 5, Issue 3 , November 2020, , Pages 110-114
Abstract
Background & Objective: Cervical cancer is the fourth most common cancer in women worldwide. HPV is a heterogeneous virus, and a persistent high-risk HPV infection contributes to cancer development. This study aims to determine the relative frequency of HPV genotypes in Kerman, Iran.Materials & ...
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Background & Objective: Cervical cancer is the fourth most common cancer in women worldwide. HPV is a heterogeneous virus, and a persistent high-risk HPV infection contributes to cancer development. This study aims to determine the relative frequency of HPV genotypes in Kerman, Iran.Materials & Methods: This cross-sectional study was conducted on 50 women with Pap smear samples, referring to a general laboratory in Kerman, Iran. Detecting two HPV genotypes was carried out using Multiplex Polymerase Chain Reaction (PCR) technique. The sociodemographic survey was conducted for each HPV-positive woman. Results: Out of 50 cervical cancer patients, 33 women (66%) were HPV 16, 18-positive. HPV 16 (38%) was the most rampant type, followed by HPV 18 (14%) and HPV 16, 18 (14%).Conclusion: Studying the prevalence of HPV genotypes and their respective risk factors can lead to efficient vaccine development against the virus in each geographical area. It can also be beneficial for illness management and high sensitivity diagnosis of cervical intraepithelial neoplasia.
Obstetrics and Gynecology
Khadije Saravani; Pantea Ramezannezhad; Razieh Behzadmehr; Rezvaneh Behzadmehr; Saeide Saeidi
Volume 5, Issue 3 , November 2020, , Pages 126-130
Abstract
Background & Objective: In this study, the relationship between ultrasonic marker of fetal lung maturity and lamellar body number was studied.Materials & Methods: A comprehensive literature review was performed on papers published from 2004 to 2016 by searching databases including NCBI, Science ...
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Background & Objective: In this study, the relationship between ultrasonic marker of fetal lung maturity and lamellar body number was studied.Materials & Methods: A comprehensive literature review was performed on papers published from 2004 to 2016 by searching databases including NCBI, Science Direct, Springer, and Web of Science as well as native databases such as Iran DAC, Islamic science citation (ISC), and Magiran with a special focus on presented articles. Keywords used include body count, fetal lung, and ultrasonic.Results: In this study we used ultrasonic marker of fetal lung maturity and related this to lamellar body count and neo natal outcome. The ultrasonic marker of fetal lung maturity can reduce mortality and morbidity in neonate.Conclusion: A limited study has been performed in the field of ultrasonic marker of fetal lung maturity and it is suggested that detailed studies be performed in this field in other parts of Iran as well.