Maliheh Arab; Giti Noghabaei; Ghazaleh Fazli; Golnaz Fallah-Talouki; Hamed Tahmasebi; Masoomeh Raoufi; Behnaz Ghavami
Articles in Press, Accepted Manuscript, Available Online from 14 November 2022
Abstract
Introduction: Low-grade appendiceal mucinous neoplasm (LAMN) is a very rare condition, diagnosed in 0.2-0.7 % of appendectomies. Pathophysiology of the neoplasm involves accumulation of large volume of mucin in appendiceal lumen, resulting in its obstructive dilation. Most epithelial tumors affecting ...
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Introduction: Low-grade appendiceal mucinous neoplasm (LAMN) is a very rare condition, diagnosed in 0.2-0.7 % of appendectomies. Pathophysiology of the neoplasm involves accumulation of large volume of mucin in appendiceal lumen, resulting in its obstructive dilation. Most epithelial tumors affecting appendix are of the mucinous type and are manifested by mucin accumulation within an inflamed appendix with fibrotic and hyalinized wall.Case presentation: A 29-year-old female presented with history of chronic and intermittent episodes of abdominal pain and a palpable mass in the right lower abdominal quadrant. Sonography showed a 58 mm mass anterior to the uterus and adjacent to the ovary, probably a uterine myoma. Laparotomy revealed normal uterus, and ovaries with a translucent mass originating from appendix and fixed to cecum. Pathologic examination of the mass was reported as low grade appendiceal mucinous neoplasm.Conclusion: This is a rare case of appendiceal mucocele in a young female, mimicking pelvic mass, which was misinterpreted by sonography as gynecologic solid mass near uterus. Preoperative diagnosis of appendiceal mucocele is important due to the risk of concurrent GI and ovarian malignancy associated with the condition.Keywords: Mucocele; Appendix; pseudomyxoma peritonei; low-grade appendiceal mucinous neoplasm
Maliheh Arab; Nafiseh poorzad; Giti Noghabaei; Ghazaleh Fazli; Behnaz Ghavami; Tayebeh jahed Bozorgan
Articles in Press, Accepted Manuscript, Available Online from 14 November 2022
Abstract
Cancer survivorship care tries to discover improved healthy lifestyles for cancer patients, rather than just managing the complications; thus, it seems necessary to identify the aspects associated with general well-being in order to design proper care, and confront difficulties that cancer survivors ...
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Cancer survivorship care tries to discover improved healthy lifestyles for cancer patients, rather than just managing the complications; thus, it seems necessary to identify the aspects associated with general well-being in order to design proper care, and confront difficulties that cancer survivors encounter such as anxiety, depression, cognitive dysfunction, weakness and fatigue, pain, sexual dysfunction, and sleep disorders (1-4). Cancer survivorship assessment from the National Comprehensive Cancer Network clinical practice guidelines in oncology (NCCN guidelines. survivorship, version 2.2020) is one of the most common and valid tools for measuring the quality of life in cancer survivors (3-6).Gynecological cancer survivors have been growing, as a result of advancements in national cancer screening strategies, resulting in early-stage diagnosis, and cancer treatments developments; thus, general mortality to incidence ratios have been declined from 2000 to 2015, in Iran. However, lack of a valid documented assessment tool to measure their requirements for supportive care is detected (7). It seems indispensable to provide a translated adapted version of NCCN survivorship questionnaire, to offer the Iranian cancer care providers have the prospect in comparison and approaches in a transcultural framework. The present study proposed to represent a renovated double back translation to revise and culturally adapt the original English version of cancer survivors’ assessment questionnaire into the Persian version in order to achieve a reliable tool that meets the clinical research needs of Iranian researchers at the desired level. The aim was to develop a comprehensive scale that comprises all features of gynecologic cancer survivors` requirements in Iranian population, equivalent to NCCN guideline hypothetical concept.
Behnaz Nouri; Maliheh Arab; mohammad nasiri
Articles in Press, Accepted Manuscript, Available Online from 14 November 2022
Abstract
Background and Objective: Endometriosis is one of the most common diseases in the female population. The range of diagnostic delays in this disease is long and leads to adverse health-related consequences. The aim of this study was to evaluate diagnostic experiences in patients with endometriosis who ...
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Background and Objective: Endometriosis is one of the most common diseases in the female population. The range of diagnostic delays in this disease is long and leads to adverse health-related consequences. The aim of this study was to evaluate diagnostic experiences in patients with endometriosis who are candidates for laparoscopic surgery.Methods: This cross-sectional study was performed on 433 patients with endometriosis who were candidates for laparoscopic surgery referred to Shohada-Tajrish Hospital in Tehran between January 2016 and December 2021. A questionnaire including demographic and clinical information, MRI, and pathology reports were collected from participants. The MRI lesions were segmented and the results were compared with pathology and clinical examination. For statistical analysis SPSS software, version 22 was used.Results: A total of 433 patients in this study with a mean age of 34.18±7.99. The average estimated duration of disease symptoms (months) was 40.58±42.33. The predictive value of clinical symptoms is weak compared to MRI. However, the probability that the disease is not present when the clinical signs be negative is acceptable in most of the endometriosis sites. MRI considerably shows the true negative rate, but its sensitivity is only relatively acceptable for the diagnosis of ascites (67.66%). Calculating the accuracy of MRI reports probably shows the overall classification of the patients via MRI test.Conclusion: despite extensive research, there are no suitable and accurate non-invasive methods for diagnosing endometriosis. MRI and clinical examination alone are not useful for definitive diagnosis and it is better to examine biomarkers and artificial intelligence for non-invasive and accurate diagnosis of this disease.
Gynecology Oncology
Maryam Talayeh; Maliheh Arab; Somayyeh Noei Teymoordash; Noushin Afsharmoghadam; Masoomeh Raoufi; Behnaz Ghavami; Mahsa Asghari
Volume 7, Issue 6 , September and October 2022, , Pages 569-573
Abstract
Endometrial stromal sarcoma is a rare condition, constituting nearly 0.2% of all reproductive tract malignancies. The condition mainly affects the peri-menopausal population; however, it can occasionally be found in younger women and adolescents. Here, this is a case of a 20-year-old primiparous ...
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Endometrial stromal sarcoma is a rare condition, constituting nearly 0.2% of all reproductive tract malignancies. The condition mainly affects the peri-menopausal population; however, it can occasionally be found in younger women and adolescents. Here, this is a case of a 20-year-old primiparous female who was referred to us with the main complaint of vaginal bleeding (menometrorrhagia), ongoing for 6 months after delivery. Her sonography report indicated a 5 cm intra-cavitary mass suspicious for myoma or placental polyp. Given the pathology report of low-grade endometrial stromal sarcoma (LGESS) on samples obtained through hysteroscopy and D&C, she underwent total abdominal hysterectomy and bilateral salpingo-oophorectomy (TAH+BSO). Endometrial stromal sarcoma is a rare uterine malignancy of mesenchymal origin that should be considered, even in very young patients.
Gynecology Oncology
Behnaz Nouri; Sara Sarani; Maliheh Arab; Mina Bakhshali-Bakhtiari; Fereshte Sarbazi; Anita Karimi
Volume 7, Issue 4 , March and April 2022, , Pages 361-361
Abstract
CORRIGENDUM : In the version of this article initially published, the name of author Mina Bakhshali-Bakhtiari was incorrectly written as Mina Bakhtiari.[J. Obstet. Gynecol. Cancer Res. 2022;7(3):230-234] published article with the doi of http://dx.doi.org/10.30699/jogcr.7.3.230
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CORRIGENDUM : In the version of this article initially published, the name of author Mina Bakhshali-Bakhtiari was incorrectly written as Mina Bakhtiari.[J. Obstet. Gynecol. Cancer Res. 2022;7(3):230-234] published article with the doi of http://dx.doi.org/10.30699/jogcr.7.3.230
Gynecology Oncology
Behnaz Nouri; Sara Sarani; Maliheh Arab; Mina Bakhtiari; Fereshte Sarbazi; Anita Karimi
Volume 7, Issue 3 , January and February 2022, , Pages 230-234
Abstract
Background and Objectives: Adnexal masses are among the most important neoplastic lesions observed in women. Considering different results of laparoscopy versus laparotomy for adnexal masses, this study compared the surgical consequences of laparoscopy and laparotomy of adnexal masses.Methods: This prospective ...
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Background and Objectives: Adnexal masses are among the most important neoplastic lesions observed in women. Considering different results of laparoscopy versus laparotomy for adnexal masses, this study compared the surgical consequences of laparoscopy and laparotomy of adnexal masses.Methods: This prospective observational study was performed on females aged 10 to 75 years with adnexal mass referred to the gynecology clinic of Shohaday-e Tajrish Hospital (2019-2020) by convenience sampling. A total of 34 patients in the laparoscopy group and 29 patients in the laparotomy group were included in the study. SPSS 25 was used for data analysis.Results: The mean duration of surgery and anesthesia in laparoscopic patients was significantly more than in the laparotomy patients (P < /em><0.05). There were no significant differences between patients in the two groups in terms of complications during surgery (P < /em>=0.62). The mean of pre-discharge pain (based on scoring from 1 to 10) in laparoscopic patients was significantly lower than in the laparotomy group (3.5 ± 1.2 and 6.7 ± 1.0, respectively, P < /em><0.001). The mean length of hospital stay after surgery was significantly lower in the laparoscopic group compared with the laparotomy group (29 ± 9 hours and 44 ± 7 hours, respectively, P < /em><0.001).Conclusion: Although the use of laparoscopy in adnexal masses is associated with a longer duration of surgery and anesthesia, due to the shorter hospital stay, it can be concluded that the use of laparoscopy in adnexal masses is better than laparotomy.
Gynecology Oncology
Somayyeh Noei Teymoordash; Maliheh Arab; Maryam Talayeh; Masoomeh Raoufi; Behnaz Ghavami; Behnaz Nouri
Volume 6, Issue 2 , March 2021, , Pages 99-104
Abstract
Background: A variety of presentations may be manifested by retained sponge, including intestinal obstruction, intestinal fistula, malabsorption syndrome and chronic pain from adhesions; in some cases, it may have an asymptomatic clinical course.Case report: In a 41-year-old female, gravida 4 para 4, ...
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Background: A variety of presentations may be manifested by retained sponge, including intestinal obstruction, intestinal fistula, malabsorption syndrome and chronic pain from adhesions; in some cases, it may have an asymptomatic clinical course.Case report: In a 41-year-old female, gravida 4 para 4, with a history of laparotomy performed for an ovarian adenocarcinoma three years prior to her referral, a gossypiboma was incidentally detected on follow up imaging. The gossypiboma was safely excised by a midline laparotomy.Conclusion: Asymptomatic gossypiboma should be considered in patients presenting with a mass, who have undergone laparotomy in the past.
Gynecology Oncology
Somayyeh Noei Teymoordash; Maliheh Arab; Noushin Afsharmoghadam; Behnaz Nouri; Tayebeh Jahed bozorgan; Maryam Talayeh
Volume 5, Issue 3 , November 2020, , Pages 103-109
Abstract
Pseudomyxoma peritonei (PMP) is characterized by mucinous ascites in the peritoneal cavity and might involve the omentum and peritoneum. The PMPs originating from the ovary are mostly caused by ruptured ovarian mature teratomas and mucinous ovarian carcinomas. The present case is a rare advanced mucinous ...
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Pseudomyxoma peritonei (PMP) is characterized by mucinous ascites in the peritoneal cavity and might involve the omentum and peritoneum. The PMPs originating from the ovary are mostly caused by ruptured ovarian mature teratomas and mucinous ovarian carcinomas. The present case is a rare advanced mucinous borderline ovarian tumor and late recurrence in PMP in a 52-year-old menopaused woman. She presented with gradual abdominal enlargement and cystic abdominopelvic lesion with internal septa and ascites. The patient underwent total abdominal hysterectomy, bilateral salpingo-oophorectomy, infracolic omentectomy, lymphadenectomy, and appendectomy. Histopathologic examination revealed mucinous borderline tumors. About 5.5 years after the first surgery, she presented with abdominal bloating and a sonography report of peritoneal seeding in the abdomen and pelvis. Abdominal exploration showed gelatinous-mucinous ascites and disseminated peritoneal carcinomatosis. The final histopathologic evaluation indicated PMP. Although the recurrence of mucinous borderline tumors is in an average of two years, the present case had relapsed after 5.5 years as pseudomyxoma with borderline pathology.
Nafiseh Faghih; Maliheh Arab
Volume 3, Issue 4 , November and December 2018, , Pages 169-171
Abstract
Background & Objective: Endometrial cancer is one of the most common gynecologic malignancies in developed countries. Survival rate in metastatic endometrial adenocarcinoma recurrence is reduced, and treatment in these patients is mostly palliative. One of the therapeutic options in the endometrial ...
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Background & Objective: Endometrial cancer is one of the most common gynecologic malignancies in developed countries. Survival rate in metastatic endometrial adenocarcinoma recurrence is reduced, and treatment in these patients is mostly palliative. One of the therapeutic options in the endometrial adenocarcinoma recurrence is hormone therapy. The expected response to the hormonal treatment is about 10-20%.
Case Report: This is a case report from 57-year-old woman suffering from stage IA - Grade 1 endometrial cancer, who had vaginal carcinoma recurrence with liver and pulmonary metastasis 5.5 years after the initial treatment. Due to positive hormone receptor and the pathological profile of the tumor, hormone therapy with tamoxifen and megestrol was started. The treatment evaluation revealed complete response within five months with clearance of lung and liver metastatic lesions. There is no evidence of disease and metastases in the patient's examination and imaging after 3 years of starting hormone therapy.
Conclusion: In the case of well-differentiated recurrent and metastatic endometrial cancer, good response to the hormone therapy by the least complications might be achieved.
