Sedigheh Borna; Nasim Khorami; Azin Ghamari; Fahimeh Ghotbizadeh Vahdani
Volume 4, Issue 1 , March and April 2019, , Pages 24-28
Abstract
Background & Objective: This prospective study aimed to determine the relationship between maternal and amniotic fluid (AF) lipid profiles in the second trimester with pregnancy outcomes.
Materials & Methods: One hundred-eighty singleton pregnant women, with a gestational age of 16-22 weeks, ...
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Background & Objective: This prospective study aimed to determine the relationship between maternal and amniotic fluid (AF) lipid profiles in the second trimester with pregnancy outcomes.
Materials & Methods: One hundred-eighty singleton pregnant women, with a gestational age of 16-22 weeks, were enrolled in this study. All women underwent amniocentesis, and 2 mL of AF was investigated for AF lipid profile. Furthermore, the serum maternal lipid profile was evaluated simultaneously. All participants were followed up until the delivery, and postnatal outcomes were recorded.
Results: Mean maternal age and body mass index (BMI) of all participants were 5.8±33 years and 25.6±2.8 kg/m2, respectively. Mean maternal estriol, cholesterol, and triglyceride levels, as well as mean cholesterol and triglyceride levels of AF, were significantly different between term and preterm; intrauterine growth retardation (IUGR) and non-intrauterine growth retardation (non-IUGR); and low birth weight and normal weight neonates (P < /em><0.001). The AF cholesterol level was an independent predictor of term or preterm delivery, while the maternal estriol level was an independent predictor of IUGR or normal growth.
Conclusion: Maternal and amniotic fluid lipid profiles could be good indicatives of fetus growth.
