Gynecology Oncology
Maliheh Hasanzadeh; Seyedeh Sara Nourbakhsh; Amir Hosein Jafarian; Parnian Malakuti
Volume 5, Issue 4 , December 2020, , Pages 175-177
Abstract
Introduction: Vaginal adenosis is one of the precursor lesions of the vaginal clear cell adenocarcinoma (CCA). The most common symptom of vaginal adenosis is abnormal vaginal pain and bleeding. About 90% of women exposed to diethylstilbestrol (DES) during pregnancy have vaginal and cervical adenosis ...
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Introduction: Vaginal adenosis is one of the precursor lesions of the vaginal clear cell adenocarcinoma (CCA). The most common symptom of vaginal adenosis is abnormal vaginal pain and bleeding. About 90% of women exposed to diethylstilbestrol (DES) during pregnancy have vaginal and cervical adenosis in female fetus. DES has been reported rarely with no history of fetal use.Case Presentation: In this article, we report two vaginal adenosis patients with no history of DES during pregnancy. There was no vaginal cancer in the follow-up of the patients.Conclusion: Vaginal adenosis is considered as a non-common differential diagnosis of vaginal bleeding that can be diagnosed by physical examination, colposcopy, and biopsy.
Malihe Hasanzadeh; Fereshteh Bazmi; Parnian Malakuti
Volume 4, Issue 3 , September and October 2019, , Pages 127-130
Abstract
Background & Objective: Ovarian microcystic stromal tumor (MST) is a rare subset of ovarian tumors, that usually appears in the form of a pelvic mass which is often unilateral, and has a microcystic realization characterized by small, elliptical, and circular cysts. This microcystic stromal tumor ...
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Background & Objective: Ovarian microcystic stromal tumor (MST) is a rare subset of ovarian tumors, that usually appears in the form of a pelvic mass which is often unilateral, and has a microcystic realization characterized by small, elliptical, and circular cysts. This microcystic stromal tumor is a type of ovarian insufficiency that has recently come to researchers’ attention. However, no meta-cognitive studies have beem conducted regarding the issue. This tumor morphologically and histologically may look very similar to granulosa cell tumor, Sertoli, Lydic and other ovarian tumors but different characteristic of immunohistochemistry, genetic and gene mutation incidence makes it different. Herein, we report a rare case of the microcystic stromal tumor using immunohistochemistry studies.
Case Report: A 60-year-old woman with ovarian mass referred to gynecology clinic in March 2018. She underwent total abdominal hysterectomy and bilateral Salpingo-oophorectomy. Pathology results showed ovarian microcystic stromal tumor. The patient was fallowed up without any intervention after surgery. To date she is alive with no problem.
Conclusion: Ovarian MST is a rare tumor that originates from the ovarian stroma, which is histologically confused with a number of ovarian tumors, especially metastatic tumors. Immunohistochemistry findings are very helpful in differentiating this tumor from other tumors and preventing diagnostic errors.
