Gynecology Oncology
Fereshteh Fakour; Zahra Rafiei Sorouri; Amirhossein Hajizadeh Fallah; Atefeh Mousavi; Maral Farahmand
Volume 8, Issue 2 , March and April 2023, , Pages 173-180
Abstract
Background & Objective: In Iranian women, the age of breast cancer is 10-20 years earlier than women living in developed countries. Moreover, HPV infection has increased among Iranian women and it is more common compared to European women. The purpose of the present study is to investigate the ...
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Background & Objective: In Iranian women, the age of breast cancer is 10-20 years earlier than women living in developed countries. Moreover, HPV infection has increased among Iranian women and it is more common compared to European women. The purpose of the present study is to investigate the role of HPV as a potential risk factor for breast cancer at younger ages.Materials & Methods: This study is a case-control study that was performed on 46 specimens of breast cancer tissue and 46 samples of normal breast tissue with no malignancy. In coordination with the pathology laboratory of Poursina Hospital (Rasht, Iran), samples of breast cancer pathology templates that were available in the laboratory archives were selected after a preliminary examination of the accuracy of tissue diagnosis. After that, a tissue incision was prepared with H&E staining and the cancer diagnosis was again confirmed by a pathologist. Samples were cut with a microtome with disposable blades. Then the tissue sample was deparaffinized and its DNA was extracted. The data were analyzed by SPSS software version 21 (IBM SPSS, Armonk, NY, USA) using Chi-square, T-test, variance analysis and logistic regression.Results: The results showed a significant difference between the two groups of women with breast cancer and without malignancy in the age of first pregnancy and gravidity. There was a significant difference in human papillomavirus type 16 infection between the two groups with breast cancer and without malignancy. The logistic regression model examined the effect of all variables and showed that infection with human papillomavirus type 16 increased the risk of breast cancer by 4.6 times, taking into account other variables.Conclusion: The present study, independent of other studies, showed that human papillomavirus type 16 could be a risk factor for breast cancer. If the virus is found in an individual, it is recommended that the patient be monitored frequently and more detailed examinations for breast malignancies be performed.
Obstetrics and Gynecology
Atefeh Mousavi; Sharareh Jannesari; Sepideh Hajian; Mahnaz Solhi; Mehdi Khabaz Khoob; Malihe Nasiri; Aryan Sadeghyan
Volume 7, Issue 4 , March and April 2022, , Pages 304-313
Abstract
Background & Objective: Breast cancer is the most common type of cancer and about one-third of all cancers in women. Within the case of early detection, more than 90% of the patients are treated. However, most women do not perform breast self-examination as a simple, effective, and inexpensive way ...
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Background & Objective: Breast cancer is the most common type of cancer and about one-third of all cancers in women. Within the case of early detection, more than 90% of the patients are treated. However, most women do not perform breast self-examination as a simple, effective, and inexpensive way to prevent cancer deaths. Therefore, this study aimed to inform and educate women to promote self-efficacy and encourage individuals to self-care.Materials & Methods: This study is quantitative research and was conducted on 80 women aged 20-60 years old in health centers of the city of Some Sara. The data collection tool was a researcher-made questionnaire designed based on the Extended Parallel Process Model. The educational intervention was conducted using lecture, question and answer, movie screening, and practical presentation using Moulage. The health behaviors and performance of the participants before and immediately after the intervention, and two months later, were compared within the intervention and control groups. Data were analyzed by repeated-measures test, chi-square, Mann -Whitney, Exact Fisher's test.Results: The study results showed that educational intervention based on the Extended Parallel Process Model had increased self-efficacy within the intervention group compared with the control group. The intervention increased the average score of individuals from model structures. So that before the educational intervention, the average perceived susceptibility and severity score, perceived self-efficacy and response efficacy, perceived threat, and perceived efficacy was moderate. After the intervention, the average score of all model components increased (P < /em><0/05). The mean score of the performance checklist was 14 before the intervention, which was upgraded to 20 after the intervention (P < /em><0/05).Conclusion: The results of this study supported the effectiveness of the Extended Parallel Process Model in preventing breast cancer.
