Iranian Society of Gynecology Oncology
Obstetrics and Gynecology
The Effect of Metformin in Preventing of Superimposed Preeclampsia: a Randomized Clinical Trial

Shahnaz Ahmadi; Elnaz Salarifar; Kambiz Ahmadi; Maryam Rahimi; Mahshid Bahraini

Volume 7, Issue 5 , July and August 2022, , Pages 399-404

Abstract
  Background & Objective: Preeclampsia is associated with the release of soluble endoglin (sENG) into the maternal circulation. It inhibits sENG secretion, inhibiting the complex I of the mitochondrial electron transport chain. Therefore, using metformin may be helpful in the prevention of preeclampsia. ...  Read More