Iranian Society of Gynecology Oncology
Gynecology Oncology
The Importance of RTK Signaling Genes and their Inhibitors in Breast Cancer

Maryam Rahimi; Setareh Talebi Kakroodi; Mansoureh Tajvidi

Volume 7, Issue 4 , March and April 2022, , Pages 258-271

Abstract
  Receptor tyrosine kinase (RTK) signaling is a crucial pathway in the development of many cancers. KIT, PI3K, and AKT are the major genes in this pathway. KIT RTK functions in cell signal transduction in various cell types, such as cancer cells. A central element of RTK signaling is phosphatidylinositol-4, ...  Read More