Marzieh Mehrafza; Azadeh Raoufi; Tahereh Zare Yousefi; Elmira Hosseinzadeh; Sajedeh Samadnia; Amirhossein Tamimi; Ahmad Hosseini
Articles in Press, Accepted Manuscript, Available Online from 14 November 2022
Abstract
Background and Objective: Repeated implantation failure (RIF) is still remain an ongoing challenge. RIF may be contributed to the embryo or the endometrium, which any abnormalities of each two may result implantation failure. The aim of present study was to report the effect of endometrial injury (EI) ...
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Background and Objective: Repeated implantation failure (RIF) is still remain an ongoing challenge. RIF may be contributed to the embryo or the endometrium, which any abnormalities of each two may result implantation failure. The aim of present study was to report the effect of endometrial injury (EI) during frozen embryo transfer (FET) on pregnancy outcome in RIF patients.Material and methods: In this retrospective case series, since 2018 to 2020, 20 patients with a history of RIF who underwent EI during FET cycle were evaluated. Results: Chemical, clinical and ongoing pregnancy and live birth was achieved in 8 (40%), 7 (35%), 6 (30%) and 6 (30%) patients, respectively.Conclusion: The present study shows that using EI in FET cycle is a feasible, safe and efficient method in improving clinical outcomes. More researches are needed to find out the real effect of EI during FET in RIF patients.
Gynecology Oncology
Soheila Aminimoghaddam; Zahra Vahedpoor; Shabnam Bozorgzadeh
Volume 8, Issue 4 , July and August 2023, , Pages 417-421
Abstract
Hereditary non polyposis colorectal cancer (HNPCC) also known as Lynch syndrome (LS), is an autosomal dominant cancer syndrome. Besides colorectal cancers, it predisposes patients to extracolonic cancers. Despite several extracolonic cancers have been reported on LS, we found a new face of it. A 43-year-old ...
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Hereditary non polyposis colorectal cancer (HNPCC) also known as Lynch syndrome (LS), is an autosomal dominant cancer syndrome. Besides colorectal cancers, it predisposes patients to extracolonic cancers. Despite several extracolonic cancers have been reported on LS, we found a new face of it. A 43-year-old G2L2 patient with chief complaint of abnormal uterine bleeding. Her endometrium biopsy showed clear cell carcinoma, and the necessary work-ups have been done. But the patient's family history demonstrated HNPCC based on the Amsterdam 2 criteria. After some years, the patient presented to our hospital for fever, shivering and abdominal LUQ pain. Spiral CT scan showed a solid cyst with heterogeneous enhancement in the spleen, and hepatosplenomegaly. In this paper, another case with endometrial cancer as a sentinel cancer of LS is reported. This fact implicate that physicians should notice the family history of malignancies in patients with gynecologic cancers and consider LS.
Pathology
Nahid Ghanbarzadeh; Ali Nadjfai-Semnani; Mohammad Nadjafi-Semnani; Mahmoodreza Behravan; Majid Zare-Bidaki
Volume 8, Issue 2 , March and April 2023, , Pages 184-187
Abstract
Echinococcus granulosus (sensu lato) is the main cause of Cystic hydatid in human and livestock in the world and is considered a neglected tropical disease. Hydatid cysts often form in the liver (50–70%) and less frequently the lung, spleen, kidney, bone, brain and genital system. Ovarian hydatid ...
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Echinococcus granulosus (sensu lato) is the main cause of Cystic hydatid in human and livestock in the world and is considered a neglected tropical disease. Hydatid cysts often form in the liver (50–70%) and less frequently the lung, spleen, kidney, bone, brain and genital system. Ovarian hydatid cyst is one of the rarest cases with nonspecific clinical presentation. Here in a case report study, we report a primary unilateral ovarian hydatid cyst in a 45-years-old woman. This patient was presented with a large pelvic mass. A pelvic multiloculated mass in abdominal ultrasound and a solid-cystic lesion of the left adnexa in CT scan were reported. All other laboratory tests and chest X-ray showed typical results. Molecular method was performed to confirm radiography and staining methods. A cystic mass on the left fallopian tube and ovary was found in the patient's laparotomy and all were resected with the appearance of a tubo-ovarian abscess. Postoperative pathological and molecular diagnosis confirmed a hydatid cyst disease. Five years of follow-up revealed no recurrence of the disease. Hydatid cyst can.
Gynecology Oncology
Maliheh Hasanzadeh; Seyedeh Sara Nourbakhsh; Amir Hosein Jafarian; Parnian Malakuti
Volume 5, Issue 4 , December 2020, , Pages 175-177
Abstract
Introduction: Vaginal adenosis is one of the precursor lesions of the vaginal clear cell adenocarcinoma (CCA). The most common symptom of vaginal adenosis is abnormal vaginal pain and bleeding. About 90% of women exposed to diethylstilbestrol (DES) during pregnancy have vaginal and cervical adenosis ...
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Introduction: Vaginal adenosis is one of the precursor lesions of the vaginal clear cell adenocarcinoma (CCA). The most common symptom of vaginal adenosis is abnormal vaginal pain and bleeding. About 90% of women exposed to diethylstilbestrol (DES) during pregnancy have vaginal and cervical adenosis in female fetus. DES has been reported rarely with no history of fetal use.Case Presentation: In this article, we report two vaginal adenosis patients with no history of DES during pregnancy. There was no vaginal cancer in the follow-up of the patients.Conclusion: Vaginal adenosis is considered as a non-common differential diagnosis of vaginal bleeding that can be diagnosed by physical examination, colposcopy, and biopsy.
