Gynecology Oncology
Sedigheh Ghasemian Dizajmehr; Mahsa Mohammadi Irvanlou; Afshin Mohammadi; Farzaneh Rashidi Fakari
Volume 8, Issue 3 , May and June 2023, , Pages 295-300
Abstract
Background & Objective: Ovarian mature cystic teratomas (OMCTS) are one of the most common benign ovarian tumors. Most MCTs can be diagnosed by ultrasonography (us). Due to heterogeneous composition and a variety of appearance, in some non-diagnostic imaging reports it is suggested that we evaluate ...
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Background & Objective: Ovarian mature cystic teratomas (OMCTS) are one of the most common benign ovarian tumors. Most MCTs can be diagnosed by ultrasonography (us). Due to heterogeneous composition and a variety of appearance, in some non-diagnostic imaging reports it is suggested that we evaluate some tumor markers (CA125 and CA19-9) to complement imaging modalities. According to previous investigation, a single elevated CA 19-9 is in association with specific radio-pathologic features, such as size, torsion, bronchial glands, fat and teeth components. Here we are presenting three different cases of OMCT with different characteristics.Case Presentation: Case 1: asymptomatic, non-diagnostic US, single- elevated CA19-9, smaller than in 10 cm with bronchial glands and fat component. Case 2: symptomatic, non-diagnostic U.S. normal CA19-9, larger than 10 cm with torsion and necrosis. Case 3: symptomatic, diagnostic US, single- elevated CA19-9, smaller than 10 cm, full of hair and sebaceous material. Computer tomography (CT), in all of our cases was diagnostic based on OMCT. Apologia of pathologic pathway of elevated CA19-9 in both cases 1 and 3 were in agreement with the result of previous investigations. In case 2, despite its large size and torsion, CA 19-9 level was low.Conclusion: Single- elevated CA 19-9 level in OMCTs could impact benign characteristics of this kind of tumor.
Gynecology Oncology
Fatemeh Shafizadeh; Sara Babazadeh; Fatemeh Nasiri Amiri; Ahmadreza Shafizadeh
Volume 6, Issue 4 , August 2021, , Pages 233-238
Abstract
Mature cystic teratomas, also named dermoid cysts, are the most benign ovarian germ cell tumors and can occur in any age group. Transformation of the mature elements within the dermoid cyst to the malignancy termed mature cystic teratomas (MCTs) with malignant transformation occurs in only 1-2 % of cases. ...
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Mature cystic teratomas, also named dermoid cysts, are the most benign ovarian germ cell tumors and can occur in any age group. Transformation of the mature elements within the dermoid cyst to the malignancy termed mature cystic teratomas (MCTs) with malignant transformation occurs in only 1-2 % of cases. Of these, squamous cell carcinoma (SCC) with 80% prevalence is the most common type. A 54-year-old peri-menopausal woman -gravida 5, para 4, live 4, and abortion 1- presented to our clinic with a complaint of abdominal pain for about five months. Transvaginal ultrasonography revealed a mass with a diameter of 125-millimeter in the left adnexa with a complex appearance containing fine-echo liquid, solid internal component, and thickened wall. Spiral CT scan of abdomen & pelvis showed 147×121-millimeter bilocular lesion consistent with an ovarian dermoid cyst. Left salpingo-oophorectomy was performed, and a frozen section was requested during the surgery, which showed a malignant epithelial tumor consistent with squamous cell carcinoma arising in teratoma. Total abdominal hysterectomy, bilateral salpingo-oophorectomy, pelvic lymphadenectomy, and partial omentectomy were done successfully. The patient was discharged from the hospital after two days without any complaints or adverse events. Regarding the rarity of MCT with malignant transformation, it is recommended to consider patient characteristics, preoperative imaging, laboratory evaluations, and the results of the frozen section during surgery since they can significantly change the treatment plan and the prognosis of the patient.
Abed Ebrahimi; Frogh Pourgholam; Mahbobeh Rostami; Farzad Abaszadeh; Behzad Gholamveisi
Volume 4, Issue 4 , September and October 2019, , Pages 155-159
Abstract
Background & Objective: Mature cystic teratomas are rare neoplasms and consist of at least two to three embryonic layers. While these tumors are most commonly seen in the testes and ovaries, they have been reported elsewhere.
Case Report: A 22-year-old female patient referred to Mehr Hospital in ...
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Background & Objective: Mature cystic teratomas are rare neoplasms and consist of at least two to three embryonic layers. While these tumors are most commonly seen in the testes and ovaries, they have been reported elsewhere.
Case Report: A 22-year-old female patient referred to Mehr Hospital in Mashhad with symptoms of pelvic pain, tympanites, altered bowel habits, nausea, and vomiting. According to the performed examinations and evaluations, a mass of 37 × 20 mm was found in the retroperitoneum between the vagina and rectum. The patient underwent laparoscopic surgery and the cyst was completely resected. The patient was discharged a day after the surgery and no surgical complications were reported in conducted follow-ups. The pathologic finding also reported a dermoid cyst.
Conclusion: Resection surgery is the mainstay in the treatment of mature retroperitoneal teratomas. Although tumor characteristics can be diagnosed preoperatively by imaging modalities, a definitive diagnosis can only be made by histologic evaluations.
Behnaz Moradi; Mohammad Ali Kazem; Mahboobeh Shirazi
Volume 3, Issue 2 , May and June 2018, , Pages 83-86
Abstract
Introduction: Many different Doppler-derived techniques have been proposed for overall assessment of cardiovascular well-being. In this report, 3 cases of high output cardiac failure were presented with the aim of evaluating the effect of fetal weight on fetal combined cardiac output (CCO).
Patients ...
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Introduction: Many different Doppler-derived techniques have been proposed for overall assessment of cardiovascular well-being. In this report, 3 cases of high output cardiac failure were presented with the aim of evaluating the effect of fetal weight on fetal combined cardiac output (CCO).
Patients Information: The first and second cases were referred to Yas Hospital for the management of fetal anemia at 31and 29 weeks of gestation, respectively, and the third case had a large solid and vascular sacrococcygeal teratoma at 17 weeks. The fetal weight in the first case was less than 10 percentile, in the second case was in normal limit, and in the third one was above 90 percentile. Left ventricle, right ventricle, CCO, and weight-indexed CCO were assessed for both fetuses and all were above normal limit, indicating high output cardiac failure. Right to left cardiac output ratio also increased obviously.
Conclusion: The fetal growth restriction overestimates the weight-indexed CCO and the weight above 90 percentile underestimates it. In these conditions, CCO seems more precise in demonstrating the true burden on fetal heart in comparison with weight-indexed CCO.