Obstetrics and Gynecology
Amirreza Naseri; Sepideh Seyedi Sahebari; Mohammad-Salar Hosseini
Volume 7, Issue 1 , September and October 2021, , Pages 1-6
Abstract
The coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a chief concern of the international community. As of May 2021, more than 150 million cases and 3.2 million deaths have been recorded. Considering the early struggle in treating COVID-19 ...
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The coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a chief concern of the international community. As of May 2021, more than 150 million cases and 3.2 million deaths have been recorded. Considering the early struggle in treating COVID-19 patients, the researchers and clinicians have decided to try the previously available drugs according to their mechanisms of action. This article aims to review the potential drugs for COVID-19 patients during pregnancy and breastfeeding and their safety. PubMed and Scopus databases and Google Scholar engine were searched with the proper combination of the free keywords and MeSH Terms of COVID-19, SARS-CoV-2, Pregnancy, Breastfeeding, Treatment, Pharmacotherapy, Drug Therapy, and Drug Safety. All relevant clinical studies published until the end of 2020 were included in this review. Many antivirals, antibiotics, antiparasitics, and antipyretics have been proposed, but most of them are not registered for COVID-19 or have demonstrated little effect on the disease. Since there is still a long way to find an effective drug for the treatment of COVID-19, prevention is currently the most effective way. Also, prescribing drugs to these two groups of patients should be done according to the safety recommendations.
Hassan Boskabadi; Maryam Zakerihamidi; Fatemeh Bagheri
Volume 4, Issue 3 , September and October 2019, , Pages 93-98
Abstract
Background & Objective: Caesarean sections without indication, compared to normal vaginal deliveries, bring about many consequences for the mother and her fetus. Therefore, this study aimed at comparing the characteristics of neonates born by normal vaginal deliveries and caesarean sections.
Materials ...
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Background & Objective: Caesarean sections without indication, compared to normal vaginal deliveries, bring about many consequences for the mother and her fetus. Therefore, this study aimed at comparing the characteristics of neonates born by normal vaginal deliveries and caesarean sections.
Materials & Methods: In this cross-sectional study conducted from 2015 to 2019, 736 term neonates aged 3 to 12 days old with a weight > 2.5 kg and a gestational age > 37 weeks referred to a neonatal clinic were studied after obtaining their parents’ full consent. A researcher-made questionnaire examining maternal personal information, neonate’s characteristics, breastfeeding status, and the type of delivery was completed. The obtained data were analyzed via SPSS 22, using a t-test and Chi-square test.
Results: In the present study, out of the 736 term neonates, 409 neonates (55.6%) were born by normal vaginal deliveries and 327 neonates (44.4%) were born by caesarean sections. There were statistically significant differences between the two methods of delivery in terms of the frequency of breastfeeding per day (P < /em>=0.002), the frequency of urination per day (P < /em>=0.007), the first postpartum defecation time (P < /em>=0.027), and neonates’ chief complaint (P < /em>=0.004).
Conclusion: The results of the current study showed that the neonates born by normal vaginal deliveries, compared to those delivered by caesarean sections, had a more favorable status, regarding the frequency of breastfeeding, the frequency of urination per day, and the first postpartum defecation time. Moreover, the level of weight loss (g) per day and the percentage of daily weight loss were higher in the neonates born by caesarean sections compared to the other neonates.
