General Gynecology and Pelvic Floor
Zainab Abdulrazzaq Hameed; Abdul Karim salem Mahood; Zainab Abbas Hassooni
Articles in Press, Accepted Manuscript, Available Online from 30 January 2024
Abstract
Endometrial carcinoma (EC) is one of commonest ten cancers, and represents fourth most widespread malignancy in females, it mainly happen in postmenopausal women. Endometrial cancer creates from the endometrium and is classified, depend on the development mechanism, into kinds 1 and 2, which are responsive ...
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Endometrial carcinoma (EC) is one of commonest ten cancers, and represents fourth most widespread malignancy in females, it mainly happen in postmenopausal women. Endometrial cancer creates from the endometrium and is classified, depend on the development mechanism, into kinds 1 and 2, which are responsive and non-responsive to estrogen, respectively and have significantly diverse gene expression profiles. This study was carried out in Laboratories of the College of Science/ Department of Biology and in a local lab during the period between December 2021 to August 2022. The study of PCR was used to detection HOXA11 expression .We aimed to describe the histological changes of tumors malignant and benign and normal tissues of the endometrial and determine the relationships between HOXA11 expression with the histopathological variables involving, stage, grade, muscle and lymph nodes invasiveness and histological types. results shows the values of HOXA11 expression and a significant difference (P-value>0.001) between patients with endometrial cancer and control group, these results regarding the values means of HOXA11 expression a significant difference (P-value=0.021) between patients with benign tumor and the control and the values means of HOXA11 expression a significantly difference (P-value >0.001) between patients with endometrial cancer and benign tumor.
Obstetrics and Gynecology
Maryamsadat Hosseini; Farah Farzaneh; Mahsa Mirhadi; Seyed Ali Akbar Mahdavi Anari; Ladan Ajori; Saghar Salehpour; Tayebeh Jahed Bozorgan; Parichehr Pooransari; Shideh Ariana; Minoo Yaghmaei; Behnaz Nouri; Shahrzad Zadehmodarres; Sedighe Hosseini; Mehrdad Haghighi; Mir Mohammad Miri; Seyedpouzhia Shojaei; Ali Reza Mirkheshti; Dariush Abtahi; Tannaz Valadbeigi
Volume 7, Issue 4 , March and April 2022, , Pages 286-295
Abstract
Background & Objective: The COVID-19 infection remains a major pandemic threatening global health. Studies revealed that pregnant women are more prone to develop severe illness, with an increased risk of morbidity and mortality. So the objective of this study is to report the clinical presentation ...
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Background & Objective: The COVID-19 infection remains a major pandemic threatening global health. Studies revealed that pregnant women are more prone to develop severe illness, with an increased risk of morbidity and mortality. So the objective of this study is to report the clinical presentation and perinatal outcomes after COVID-19 infection during pregnancy or the puerperium.Materials & Methods: In this case series study, since February 2020, 25 pregnant women with a definitive diagnosis of the COVID-19 infection were registered. Their clinical signs and symptoms, laboratory findings, CT manifestations, pregnancy status, were recorded at the first visit, and they were followed six months after diagnosis.Results: The most common symptoms were cough, feeling feverish, and dyspnea. Twenty mothers required hospitalization, 5 out of 20 monitored in COVID-ICU. The chest CT scan demonstrated a grand glass appearance in 77% of cases among admitted patients. The total mortality rate in C-ICU (COVID-19 ICU) admitted patients were 80%.Conclusion: In this case series, among 25 pregnant women with confirmed COVID-19, the most vulnerable patients were in the early third trimester and twin pregnancy.
Pathology
Zahra Shahi; Mohammad Amin Edalatmanesh; Babak kheirkhah
Volume 5, Issue 3 , November 2020, , Pages 110-114
Abstract
Background & Objective: Cervical cancer is the fourth most common cancer in women worldwide. HPV is a heterogeneous virus, and a persistent high-risk HPV infection contributes to cancer development. This study aims to determine the relative frequency of HPV genotypes in Kerman, Iran.Materials & ...
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Background & Objective: Cervical cancer is the fourth most common cancer in women worldwide. HPV is a heterogeneous virus, and a persistent high-risk HPV infection contributes to cancer development. This study aims to determine the relative frequency of HPV genotypes in Kerman, Iran.Materials & Methods: This cross-sectional study was conducted on 50 women with Pap smear samples, referring to a general laboratory in Kerman, Iran. Detecting two HPV genotypes was carried out using Multiplex Polymerase Chain Reaction (PCR) technique. The sociodemographic survey was conducted for each HPV-positive woman. Results: Out of 50 cervical cancer patients, 33 women (66%) were HPV 16, 18-positive. HPV 16 (38%) was the most rampant type, followed by HPV 18 (14%) and HPV 16, 18 (14%).Conclusion: Studying the prevalence of HPV genotypes and their respective risk factors can lead to efficient vaccine development against the virus in each geographical area. It can also be beneficial for illness management and high sensitivity diagnosis of cervical intraepithelial neoplasia.
