%0 Journal Article %T Frequency of Malignant Ovarian Germ Cell Tumor and Distribution of Demographic Features in a Main Tertiary Hospital in Iran %J Journal of Obstetrics, Gynecology and Cancer Research %I Farname Inc. (Science-Based Research Institute; Professional Publisher of Scientific Journals) %Z 2645-3991 %A Akhavan, Setareh %A Agah, Jila %A Alipour, Abbas %D 2022 %\ 11/14/2022 %V 3 %N 2 %P 59-63 %! Frequency of Malignant Ovarian Germ Cell Tumor and Distribution of Demographic Features in a Main Tertiary Hospital in Iran %K infertility %K Ovarian Neoplasms %K Germ cell tumor %K Pregnancy %R 10.30699/jogcr.3.2.59 %X Aims: Ovarian cancer is the 4th cause of women’s mortality occurring due to cancer. Malignant germ cell tumors (GCTs) account for 5% of malignant ovarian tumors and 70% of ovarian tumors in women between the ages of 10-30 years old. The aim of the present study was to detect the frequency of malignant ovarian germ cell tumor and distribution of demographic features in the most crowded gynecology oncology clinic. Materials and Methods: This cohort descriptive-analytical study was conducted on cases with malignant ovarian tumor managed in Vali-Asr hospital, Tehran, Iran, from 2001 to 2018 (n=1540). The malignant germ cell tumors cases were extracted (n=128) and evaluated in point of epidemiologic and demographic data via the software SPSS 24. Findings: 128 patients (8.3%) had GCTs. The average age was 23.88±7.85 years. 79.7% lived in the city, 76.6% had medium economic status and 53.6% had normal body mass index. Premature puberty was revealed in one person. Karyotype XY was detected in 5 persons. About 70.3% of the patients had no parity. In parous women, the highest percentage was related to a childbirth (55.0%). A history of infertility was detected at 6.1%. In 10 patients, the tumor was detected during pregnancy. Conclusion: The highest frequency is related to the early young women with no considerable association with socioeconomic and weight status. It is possible that parity would be a protective factor for this tumor. In the case of adnexal mass during pregnancy, Malignant Germ cell tumors should be rolled out. %U https://www.jogcr.com/article_697143_f9f9385d3c6ded9985c6abaa5207a02a.pdf