%0 Journal Article %T E Cervical ripening: Intravaginal Misoprostol in Compare to Intracervical Foley Single Balloon Catheter, A Randomized Clinical Trial %J Journal of Obstetrics, Gynecology and Cancer Research %I Farname Inc. (Science-Based Research Institute; Professional Publisher of Scientific Journals) %Z 2645-3991 %A dehghan, maryam %A alameh, tajosadat %A Allameh, Zahra %A Seyed-Hoseini, zahra %D 2023 %\ 02/22/2023 %V 8 %N 2 %P 113-119 %! E Cervical ripening: Intravaginal Misoprostol in Compare to Intracervical Foley Single Balloon Catheter, A Randomized Clinical Trial %K Cervical ripening %K Misoprostol %K delivery %K catheter %R 10.30699/jogcr.8.2.113 %X Background & Objective: The aim of this study was to compare the efficacy of vaginal misoprostol with Foley balloon catheter for cervical ripening in women with singleton pregnancies and an unfavorable cervix.Materials & Methods: Eighty pregnant women with unfavorable cervix were randomly divided in two groups of Foley catheter or misoprostol modes. Cervical ripening in Foley catheter group was done with transcervical Foley catheter 18, and in misoprostol group with 25 μg single dose vaginal misoprostol (The maximum allowed dose for patients was 6 doses.). Bishop score, Apgar score, active phase duration, stage 2 duration and insertion to delivery interval were the main outcomes.Results: The mean time of ripening and the active phase in vaginal misoprostol group was significantly shorter than in Foley catheter group (2.32 versus 5.11 hours respectively, P-value = 0.0001). After intervention, Bishop score in vaginal misoprostol group was significantly more than Foley catheter group (8.70 versus 6.68 respectively, P-value = 0.0001). Insertion to delivery interval in vaginal misoprostol group was 9.54 hours and in Foley catheter group was 12.88 hours (P-value = 0.0001). The hospitalization time in Foley catheter group was significantly more than vaginal misoprostol group (P-value = 0.0001). The other outcomes were similar between groups.Conclusion: By the decreasing in the total time from insertion to birth, vaginal misoprostol was more effective than Foley catheter, as a cervical ripening method in our study. %U https://www.jogcr.com/article_697402_4650266ce67dde6da0cd2e22d4673d27.pdf