TY - JOUR ID - 697119 TI - A Unique History of the First Cases with Simultaneous Bone and Skin Metastasis in Vulvar Squamous Cell Carcinoma JO - Journal of Obstetrics, Gynecology and Cancer Research JA - JOGCR LA - en SN - 2645-3991 AU - Nasiri, Setare AU - Mousavi, Azamosadat AU - Sheikh Hasani, Shahrzad AU - Rahim Vakili, Mohammad Rahim AU - Modarres Gilani, Mitra AU - Akhavan, Setare AU - Mirzaei, Monire AD - Department Gynecology Oncology, Tehran University of Medical Sciences, Tehran, Iran AD - Department Thorax surgery, Tehran University of Medical Sciences, Tehran, Iran AD - Department Gynecology Oncology, Iran University of Medical Sciences, Tehran, Iran Y1 - 2022 PY - 2022 VL - 2 IS - 3 SP - EP - KW - Squamous cell carcinoma KW - Vulvar Cancer KW - Cutaneous Metastasis DO - 10.5812/jogcr.58708 N2 - Introduction: The incidence of vulvar cancer is nearly 5% of all gynecologic malignancies and almost 95% of vulvar cancers are squamous cell carcinoma (SCC). Recurrence is possible in 4 ways: local, regional, pelvic, and distant. In a cohort of 391 patients with vulvar SCC, distant metastasis was reported 5% .The common sites of distant metastasis are pelvic nodes, lung, and liver. Both skin and bone metastasis are rare in vulvar SCC. Case Presentation: The current report presented a 58-year-old female with the diagnosis of vulvar SCC. She was the 11th cutaneous metastasis, 13th bone metastasis, and the 1st case with simultaneous bone and skin metastasis reported in the last 60 years. Conclusions: It is necessary to consider any lesion on the vulve, especially in menopause females, and it should be the low threshold for biopsy to avoid delay in detection. After completion of selective treatment, the exact follow-up should be considered to discover metastases. UR - https://www.jogcr.com/article_697119.html L1 - https://www.jogcr.com/article_697119_57984b5418349a5ccb86b67cde99a65d.pdf ER -