TY - JOUR ID - 697287 TI - Accuracy of Fetal Cardiac Function Measured by Myocardial Performance Index in Fetal Intrauterine Growth Restriction JO - Journal of Obstetrics, Gynecology and Cancer Research JA - JOGCR LA - en SN - 2645-3991 AU - Eslamian, Laleh AU - Jamal, Ashraf AU - Marsosi, Vajiheh AU - Ahmadi, Marjan AU - Golbabaei, Alireza AU - Boustani, Paria AD - Department of Obstetrics and Gynecology, Perinatology Unit, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran AD - Department of Obstetrics and Gynecology, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran AD - Perinatology Unit, Shariati hospital, Tehran University of Medical Sciences, Tehran, Iran AD - School of Medicine, Tehran University of Medical Sciences, Tehran, Iran Y1 - 2022 PY - 2022 VL - 7 IS - 3 SP - 165 EP - 170 KW - Cardiac function KW - Fetus KW - MPI KW - Pregnant women KW - Ultrasound DO - 10.30699/jogcr.7.3.165 N2 - Background & Objective: IUGR (intrauterine growth restriction) fetuses have been known as a significant concern in clinical practice. It is associated with fetal mortality and morbidity and prenatal adverse cardiac remodeling. The aim of this study is the evaluation of the relation between MPI (myocardial performance index) abnormalities and doppler findings in both normal and IUGR fetuses.Materials & Methods: In this cross-sectional study, 400 consecutive pregnant women in Shariati Hospital, Tehran, Iran, in 2019 and 2020 underwent ultrasound assessment at 28-40 weeks, in which among the 400 performed ultrasounds, 47 fetuses with IUGR were selected as a case group, and 47 fetuses with normal weight were selected based on AGA (appropriate gestational age). Cardiac function was evaluated by measuring MPI in diastolic and systolic function in two groups. The results were compared to the IUGR (case group) and control group by SPSS software version 20.Results: In receiver operating characteristic (ROC) analysis, the AUC (area under the curve) for left ventricular MPI (LV MPI) was 0.929 (CI95%: 0.868-0.991; P < /em>=0.001), and the sensitivity and specificity values were 87% and 69.4% with a cut-off point of 0.2850. In ROC analysis, the area under the curve for RV MPI was 0.842 (CI95%: 0.741-0.942; P < /em>=0.001), and the sensitivity and specificity values were 78.3% and 63.9%, with a cut-off point 0.2850. Left and right ventricular MPI showed a significant difference statistically between the case and the control groups.Conclusion: The study showed a significant rise of MPI in IUGR fetuses. MPI can be considered as a useful parameter for evaluating the severity of growth restriction in IUGR fetuses. UR - https://www.jogcr.com/article_697287.html L1 - https://www.jogcr.com/article_697287_3997006400d15b09c674f6151672bedf.pdf ER -