Dose Weight Gain in Lean Patients with Polycystic Ovary Syndrome Improves Ovulation and Pregnancy Rates?

Elkhyat, Ahmed; Elsokary, Amal; Elshwaikh, Shereef

doi:10.30699/jogcr.9.1.70

Document Type : Original Research Article

Authors

Department of Obstetrics and Gynecology, Tanta University, Tanta, Egypt

https://doi.org/10.30699/jogcr.9.1.70

Abstract

Background & Objective: To evaluate the effect of weight gain in lean patients with polycystic ovary syndrome (PCOS) on ovulation and pregnancy rates.
Materials & Methods: Lean patients with PCOS seeking fertility were invited to participate in the study. Weight gain was commenced by dietary modifications. Patients were classified later into respondent and non-respondent. All patients were stimulated with Letrozole 2.5 mg twice daily for five days for six cycles. Ovulation and pregnancy rates were assessed.
Results: From 84 patients who were enrolled in our study, 33 patients were allocated into non responder group and 28 patients were allocated to the responder group, and it was found that despite there was statistical difference between both groups as regard weight gain, weight after six months and BMI after six months, there was no significant difference between both groups as regard the ovulation rate, pregnancy rate and complications to ovulation induction ovarian hyperstimulation syndrome (OHSS).
Conclusion: weight gain in lean PCOS patients - although non-significant- but it may improve the reproductive outcomes (ovulation rate and pregnancy rate) and the need of further study with larger number and longer duration of follow up for confirmation of these results.

Highlights

✅ Weight gain in lean PCOS patients - although non-significant- but it may improve the reproductive outcomes (ovulation rate and pregnancy rate) and the need of further study with larger number and longer duration of follow up for confirmation of these results.

Keywords

Main Subjects

Obstetrics and Gynecology

References

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Journal of Obstetrics, Gynecology and Cancer Research

Dose Weight Gain in Lean Patients with Polycystic Ovary Syndrome Improves Ovulation and Pregnancy Rates?

References

References

Volume 9, Issue 1 - Serial Number 36
January and February 2024
Pages 70-75

Dose Weight Gain in Lean Patients with Polycystic Ovary Syndrome Improves Ovulation and Pregnancy Rates?

References

References

Volume 9, Issue 1 - Serial Number 36January and February 2024Pages 70-75

Volume 9, Issue 1 - Serial Number 36
January and February 2024
Pages 70-75