Elham Shirali; Fariba Yarandi; Mostafa Safavi; Omid Hemmatian; Marjan Ghaemi
Volume 4, Issue 3 , September and October 2019, , Pages 117-119
Abstract
Background & Objective: Primary vaginal sarcomas are extremely rare and counts about 2-3% of all vaginal malignancies. We report a case with vaginal leiomyosarcoma which was treated by radical hysterectomy.
Case Report: A 46 year old woman from Iraq, referred to Yas Hospital by chief complaint of ...
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Background & Objective: Primary vaginal sarcomas are extremely rare and counts about 2-3% of all vaginal malignancies. We report a case with vaginal leiomyosarcoma which was treated by radical hysterectomy.
Case Report: A 46 year old woman from Iraq, referred to Yas Hospital by chief complaint of post-coital bleeding and a vaginal mass with pathology report of vaginal leiomyosarcoma. She underwent radical hysterectomy with bilateral salpingo-oophorectomy and partial vaginectomy (2/3 upper of the vagina). She refused to receive chemotherapy after surgery. In 3 years follow up, she did not have any recurrence.
Conclusion: Experiences about vaginal leiomyosarcoma are not sufficient due to rarity of the disease. However, based on review of the literature surgery is still the first choice followed by both chemotherapy and radiotherapy that are preferred based on current reports.
Elham Shirali; Fariba Yarandi; Nadereh Behtash; Omid Hemmatian
Volume 3, Issue 2 , May and June 2018, , Pages 87-91
Abstract
Aims: Cervical cancer is one of the most common cancer in the female since 1990. Neoadjuvant chemotherapy (NACT) uses before surgery, especially in countries with limited radiotherapy facilities. The aim of the present review was to study the effect of NACT before radical surgery in comparison with other ...
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Aims: Cervical cancer is one of the most common cancer in the female since 1990. Neoadjuvant chemotherapy (NACT) uses before surgery, especially in countries with limited radiotherapy facilities. The aim of the present review was to study the effect of NACT before radical surgery in comparison with other treatments and various clinical outcomes.
Information and Methods: This study is a systematic review and includes previous publishes about cervical cancer and effect of NACT before radical surgery. Over 40 previous studies were reviewed, none of them was case report, at least 5 studies were randomized clinical trials and 6 of them were meta-analysis or systematic review.
Findings: NACT before surgery demonstrates advantages to reduce the rate of lymph node metastasis and parametrial infiltration, so improves progression-free survival in patients with pelvic lymph node invasion (Approximately 35% of stage IB2–IIB bulky). NACT also decreases tumor volume and minimizes the need for adjuvant radiotherapy, thus NACT under consideration of quality of life and cost-effectiveness should be recommended. NACT is really effective in decreasing incidence of pathological risk factors.
Conclusion: NACT response associated with the stage of diagnosis, tumor size and pathology of the specimen (Squamous tumor has a better response than a non-squamous tumor). NACT seems to be feasible in the management of stage IB bulky cervical cancer, NACT followed by surgery represent an alternative to primary chemoradiotherapy in young and sexually active patients.
Elham Shirali; Fariba Yarandi; Majid Safavi; Omid Hemmatian
Volume 1, Issue 1 , May and June 2016
Abstract
Introduction: Early diagnosis of endometrial cancer in younger female patients has good prognosis and better survival because of lower stage and lower grade. Endometrial cancer should be diagnosed early at lower stage because of signs and symptoms of patients. We report on a usual case of endometrial ...
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Introduction: Early diagnosis of endometrial cancer in younger female patients has good prognosis and better survival because of lower stage and lower grade. Endometrial cancer should be diagnosed early at lower stage because of signs and symptoms of patients. We report on a usual case of endometrial cancer that was miss diagnosed because she insisted on the protection of her hymen and virginity.
Case Presentation: We report a usual case of endometrial cancer that was miss-diagnosed because the patient insisted on the protection of her hymen and virginity. A 32-year-old virgin female did not permit a general gynecologist for endometrial biopsy or curettage, to protect her hymen and virginity; the patient had stage IV endometrial cancer.
Conclusions: In conclusion, patients with persistent signs and symptoms should be considered for endometrial cancer especially patients with high risk factors: nulliparity, late menopause, obesity, diabetes mellitus, unopposed estrogen therapy, tamoxifen therapy, atypical endometrial hyperplasia, Lynch II syndrome, etc. However, the most important issue for patients with persistent symptoms and risk factors for endometrial cancer in highly religious countries is obtaining a document for the gynecologist that endorses patient virginity.
