Gynecology Oncology
Fereshteh Fakour; Zahra Rafiei Sorouri; Amirhossein Hajizadeh Fallah; Atefeh Mousavi; Maral Farahmand
Volume 8, Issue 2 , March and April 2023, , Pages 173-180
Abstract
Background & Objective: In Iranian women, the age of breast cancer is 10-20 years earlier than women living in developed countries. Moreover, HPV infection has increased among Iranian women and it is more common compared to European women. The purpose of the present study is to investigate the ...
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Background & Objective: In Iranian women, the age of breast cancer is 10-20 years earlier than women living in developed countries. Moreover, HPV infection has increased among Iranian women and it is more common compared to European women. The purpose of the present study is to investigate the role of HPV as a potential risk factor for breast cancer at younger ages.Materials & Methods: This study is a case-control study that was performed on 46 specimens of breast cancer tissue and 46 samples of normal breast tissue with no malignancy. In coordination with the pathology laboratory of Poursina Hospital (Rasht, Iran), samples of breast cancer pathology templates that were available in the laboratory archives were selected after a preliminary examination of the accuracy of tissue diagnosis. After that, a tissue incision was prepared with H&E staining and the cancer diagnosis was again confirmed by a pathologist. Samples were cut with a microtome with disposable blades. Then the tissue sample was deparaffinized and its DNA was extracted. The data were analyzed by SPSS software version 21 (IBM SPSS, Armonk, NY, USA) using Chi-square, T-test, variance analysis and logistic regression.Results: The results showed a significant difference between the two groups of women with breast cancer and without malignancy in the age of first pregnancy and gravidity. There was a significant difference in human papillomavirus type 16 infection between the two groups with breast cancer and without malignancy. The logistic regression model examined the effect of all variables and showed that infection with human papillomavirus type 16 increased the risk of breast cancer by 4.6 times, taking into account other variables.Conclusion: The present study, independent of other studies, showed that human papillomavirus type 16 could be a risk factor for breast cancer. If the virus is found in an individual, it is recommended that the patient be monitored frequently and more detailed examinations for breast malignancies be performed.
Obstetrics and Gynecology
Majid Zare-Bidaki; Mohammad Nadjafi Semnani; Ali Nadjafi Semnani; Nahid Ghanbarzadeh
Volume 6, Issue 3 , June 2021, , Pages 134-142
Abstract
Background & Objective: Urinary incontinence (UI) is a common disease that affects millions of people throughout their lives. It is reported that UI has a considerable economic burden on patients and communities. The aim of this study was to find out the prevalence of urinary incontinence (UI) and ...
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Background & Objective: Urinary incontinence (UI) is a common disease that affects millions of people throughout their lives. It is reported that UI has a considerable economic burden on patients and communities. The aim of this study was to find out the prevalence of urinary incontinence (UI) and its related factors among women living in Birjand city, Iran.Materials & Methods: A cross-sectional study from September 2020 to December 2020 was conducted on women 15 to 70 years living in nine areas of Birjand city. Data were gathered by researcher-made questionnaire and in-person interviews about demographic, obstetrics, and UI (stress, urge, and overflow UI) characteristics. Chi-square test was applied to analyze differences between women with and without UI about risk factors.Results: Of 3028 women (mean age 32.70±11.49 years), 828 (27.3%) reported to have UI. The rate of stress, urge, and mixed UI was 18.1%, 3.4%, and 5.9%, respectively. All types of UI were associated with age, education, BMI, chronic cough / dyspnea, constipation, diabetes mellitus, and smoking.Conclusion: Women should be continuously educated by health care providers on the risk factors and activities which can reduce their risk for UI. Further studies on women across the country may help decision makers to measure the regional burden of disease and to plan population-level interventions.
Fahimeh Ghotbizadeh Vahdani; Sedigheh Hantoushzadeh; Maryam Deldar Pasikhani; Azin Ghamari; Maryam Hajatpour; Zahra Panahi
Volume 4, Issue 2 , May and June 2019, , Pages 51-56
Abstract
Background & Objective: Due to increased rate of risk factors, the incidence of placenta accreta (PA) is increasing worldwide. This study aimed to investigate the important factors regarding the occurrence of PA, as well as outcomes and complications of Trans Abdominal Hysterectomy (TAH) in the patients ...
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Background & Objective: Due to increased rate of risk factors, the incidence of placenta accreta (PA) is increasing worldwide. This study aimed to investigate the important factors regarding the occurrence of PA, as well as outcomes and complications of Trans Abdominal Hysterectomy (TAH) in the patients with PA.
Materials & Methods: The study was performed as an observational cross-sectional study. Between March 2011 and March 2017, 177 patients, known cases of PA that undergone TAH, were enrolled in our study. Extracted data include demographic characteristics, patient’s medical history, surgical approach and complications, such as blood loss and urologic problems.
Results: The average of maternal age and gestational age were 33.6±4.70 (range= 22-43) years and 34.6±3.16 weeks, respectively. Neither maternal age (P < /em>=0.652) nor BMI (P < /em>=0.659) had significant association with abnormal placentation. Previous history of dilation & curettage (D&C) was found in 34 patients that was not related to the occurrence of the PA (P < /em>=0.508).Twenty-one (11.9%) of the patients needed urological intervention that did not associated with placental position, skin and uterine incision (P < /em>=0.258, 0.410 and 0.219). There is no relation between amount of blood loss with gestational age (P < /em>=0.7) and number of C/S (P < /em>=0.4), gestational age (P < /em>=0.7), anesthesia (P < /em>=0.2), and curettage history (P < /em>=0.3).
Conclusion: Our mortality and morbidity rate is much lower than reported ones, indicating the high-level ability, skill and knowledge of the surgeons.
