Iranian Society of Gynecology Oncology


1 Maternal, Fetal and Neonatal Research Center, Tehran University of Medical Sciences, Tehran, IR Iran

2 Department of Obstetrics and Gynecology, Faculty of Medicine, Sabzevar University of Medical Sciences, Sabzevar, IR Iran


Introduction: The incidence of very echogenic amniotic fluid on ultrasonographic examination at term pregnancy is very low and its causes and significance in outcome of pregnancy are not well- understood. In previous studies, meconium was considered to be an important cause of very echogenic amniotic fluid and follow-up with amniocentesis and fetal well-being tests were recommended; however, in recent studies vernix caseosa has been identified to be an important cause. As a result, termination of pregnancy should not be performed due to discovery of ultrasonographic echogenic amniotic fluid because it is not associated with adverse pregnancy outcomes.
Case Presentation: We report a single term pregnancy with very echogenic amniotic fluid diagnosed by ultrasonography that was terminated by cesarean section.
Conclusions: There were no adverse outcomes for the mother or neonate and the amniotic fluid was clear at the time of delivery.


  1. Petrikovsky B, Schneider EP, Gross B. Clinical significance of echogenic amniotic fluid. J Clin Ultrasound. 1998;26(4):191-3.<191::AID-JCU2>3.0.CO;2-8 [DOI:10.1002/(SICI)1097-0096(199805)26:43.0.CO;2-8]
  2. Tam G, Al-Dughaishi T. Case Report and Literature Review of Very Echogenic Amniotic Fluid at Term and Its Clinical Significance. Oman Med J. 2013;28(6). [DOI:10.5001/omj.2013.129]
  3. Sepulveda WH, Quiroz VH. Sonographic detection of echogenic amniotic fluid and its clinical significance. J Perinat Med. 1989;17(5):333-5.
  4. Mungen E, Tutuncu L, Muhcu M. Pregnancy outcome in women with echogenic amniotic fluid at term gestation. Int J Gynaecol Obstet. 2005;88(3):314-5. [DOI:10.1016/j.ijgo.2004.11.021]
  5. Benacerraf BR, Gatter MA, Ginsburgh F. Ultrasound diagnosis of meconium-stained amniotic fluid. Am J Obstet Gynecol. 1984;149(5):570-2. [DOI:10.1016/0002-9378(84)90038-3]
  6. Ram SHS, Ram S. Role of echogenic amniotic fluid particles and optical density in prediction of respiratory distress syndrome and labor. Int J Med. 2010;5(1):3-11. [DOI:10.4314/ijmu.v5i1.49287]
  7. Ram HS, Ram S. Image j analysis of amniotic fluid echogenicity and labor. Int J Gynecol Obstet. 2013;17(3):1-7.