- Maryam Deldar Pasikhani 1
- Zinat Ghanbari 1
- Fateme Talei Khatibi 2
- Ali Ganjalikhan Hakemi 3
- Elaheh Miri Ashtiani 4
1 Department of Obstetrics and Gynecology, Imam Khomeini Hospital, Tehran, Iran
2 Department of Obstetrics and Gynecology, Valiasr Hospital, Tehran University of Medical Sciences, Tehran, Iran
3 Valiasr Hospital, Tehran University of Medical Sciences, Tehran, Iran
4 Department of Physiotherapy, Faculty of Rehabilitation Sciences, Shahid Beheshti University of Medical Sciences, Damavand, Tehran, Iran
Background: Urgency is a characteristic for overactive bladder and is deﬁned by a sudden obligatory need for urination, a feeling that can be hardly stopped. Many methods such as drug therapy and feedback have been used to treat urinary incontinency.
Objectives: The aim of this study was to assess and compare the eﬀect of medication, biofeedback or biofeedback plus medication on urge- urinary incontinency and quality of life of patients.
Methods: This was a case-control randomized clinical trial performed on patients referred to Imam Khomeini hospital in 2014. Patients were divided into three groups of drug (Tolterodine), biofeedback, and biofeedback plus drug. Biofeedback group underwent two sessions of treatment weekly for four weeks, and the drug group received tolterodine (4 mg slow release) for four weeks. The third group received both of them. Quality of life and urinary incontinency symptoms were compared between the three groups and analyzed, using SPSS Version 16 software (IBM, Armonk, USA).
Results: Meaningful diﬀerences were observed between the three groups with respect to change in the total score of the questionnaire (P < 0.001). Between the groups, drug therapy had the most eﬀect on improving the total score of the questionnaire, with a mean change of 25.44 ± 1.80. No meaningful diﬀerence was observed between drug plus biofeedback and biofeedback group (P =0.114). By comparing the mean incontinency score, we found a meaningful diﬀerence between the drug and biofeedback groups and the biofeedback and biofeedback plus drug groups (P < 0.001 and P < 0.002, respectively); however, no meaningful diﬀerence was found between the biofeedback plus drug group and the drug group in mean incontinency score (P = 0.187).
Conclusions: Our study results revealed that tolterodine and biofeedback both increased quality of life indices and decreased the severity of urinary incontinency signiﬁcantly in our participants. However, drug plus biofeedback treatment improved the severity and quality of urinary incontinency, but did not improve quality of life of the patients. Therefore, physicians should consider improving the quality of life of patients as well.
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