Authors
1 Department of Gynecology Oncology, Tehran University of Medical Sciences, Tehran, Iran
2 Department of Thoracic Surgery, Tehran University of Medical Sciences, Tehran, Iran
3 Department of pathology, Tehran University of Medical Sciences, Tehran, Iran
Abstract
Introduction: Synovial sarcoma of the ovary is a very rare tumor reported only once in the past. It is the second softest tissue mass after rhabdomyosarcoma in adults but its usual site is extremities not ovary.
Case Presentation: Here we describe a 53-year-old woman with primary synovial sarcoma of the ovary with insufficient treatment and lung metastasis of the tumor.
Conclusions: Because of harmlessness symptoms, it is usually missed and correct treatment is delayed. When facing this type of tumor, referring to well-equipped centers with experienced surgeons in this field is recommended for sufficient treatment and best results.
Keywords
- Smith CJ, Ferrier AJ, Russell P, Danieletto S. Primary synovial sarcoma of the ovary: first reported case. Pathology. 2005;37(5):385-7. [DOI:10.1080/00313020500254339] [PMID]
- Mallen-St Clair J, Arshi A, Abemayor E, St John M. Factors Associated With Survival in Patients With Synovial Cell Sarcoma of the Head and Neck: An Analysis of 167 Cases Using the SEER (Surveillance, Epidemiology, and End Results) Database. JAMA Otolaryngol Head Neck Surg. 2016;142(6):576-83. [DOI:10.1001/jamaoto.2016.0384] [PMID]
- Deshmukh R, Mankin HJ, Singer S. Synovial sarcoma: the importance of size and location for survival. Clin Orthop Relat Res. 2004(419):155-61. [DOI:10.1097/00003086-200402000-00025]
- Yanan W, Wenzhi B, Gang H, Jinpeng J. Influence of neoadjuvant chemotherapy on prognosis of patients with synovial sarcoma. World J Surg Oncol. 2017;15(101). [DOI:10.1186/s12957-017-1165-9] [PMID]
- Fletcher CDM, Unni KK, Mertens F. World health organization classification of tumours: Pathology and genetics of tumours of soft tissue and bone. Lyon,France: IARC Press; 2002.
- Ladanyi M, Antonescu CR, Leung DH, Woodruff JM, Kawai A, Healey JH, et al. Impact of SYT-SSX fusion type on the clinical behavior of synovial sarcoma: a multi-institutional retrospective study of 243 patients. Cancer Res. 2002;62(1):135-40.
- Krieg AH, Hefti F, Speth BM, Jundt G, Guillou L, Exner UG, et al. Synovial sarcomas usually metastasize after >5 years: a multicenter retrospective analysis with minimum follow-up of 10 years for survivors. Ann Oncol. 2011;22(2):458-67. [DOI:10.1093/annonc/mdq394] [PMID]
- Makhlouf HR, Ahrens W, Agarwal B, Dow N, Marshalleck JJ, Lee EL, et al. Synovial sarcoma of the stomach: a clinicopathologic, immunohistochemical, and molecular genetic study of 10 cases. Am J Surg Pathol. 2008;32(2):275-81. [DOI:10.1097/PAS.0b013e31812e6a58] [PMID]
- Drozenova J, Povysil C, Tvrdik D, Babjuk M, Hanus T. [Primary synovial sarcoma of the kidney]. Cesk Patol. 2008;44(1):20-2.
- Dundr P, Fischerova D, Povysil C, Tvrdik D, Cibula D. Primary synovial sarcoma of the uterus. Pathol Oncol Res. 2012;18(2):529-33. [DOI:10.1007/s12253-011-9391-x] [PMID]
- Campbell C, Gallagher J, Dickinson I. Synovial sarcoma-towards a simplified approach to prognosis. ANZ J Surg. 2004;74(9):727-31. [DOI:10.1111/j.1445-1433.2004.03144.x] [PMID]
- Bernardo V, Harris G. Synovial cell sarcoma treatment and management. Medscape. 2016;22.
- Shields TW, LoCicero J, Reed CE, Feins RH, editors. General Thoracic Surgery. 7th ed. Philadelphia, PA: Lippincott Williams and Wilkins; 2009. p. 1619.
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