Journal of Obstetrics, Gynecology and Cancer Research

Iranian Society of Gynecology Oncology

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Examining the Association between Endometrial Thickness in Transvaginal Ultrasound and Results of Pipelle Endometrial Sampling in Perimenopausal Women with Abnormal Uterine Bleeding

Authors

Obstetrics and Gynecology Department, Medicine Faculty, Iran University of Medical Sciences, Tehran, Iran

Abstract

Aims: Since there is no consensus on the best diagnostic method for perimenopausal women with abnormal uterine bleeding. The aim of this study was to investigate the association between endometrial thickness in transvaginal ultrasound and the results of Pipelle endometrial sampling in perimenopausal women with abnormal uterine bleeding.
Materials and Methods: In this cross-sectional descriptive study, all perimenopausal women with abnormal uterine bleeding who referred to Rasoul Akram and Akbarabadi Hospitals, Tehran, Iran in 2016 and 2017 were considered. The current study was carried out on a corpus of 68 perimenopausal women with abnormal uterine bleeding. All these patients underwent a transvaginal ultrasound conducted by an operator. Afterward, all of them had a Pipelle endometrial sampling performed by a gynecologist. The current study was carried out on a corpus of 68 perimenopausal women with abnormal uterine bleeding. A chi-square, Mann Whitney, and Kruskal Wallis tests were used. The obtained data were analyzed using SPSS 22.
Findings: A statistical mean endometrial thickness in patients with benign diagnoses was 7.55±2.72mm and it was 15.57±2.99mm in patients with malignant diagnoses which indicated no statistically significant difference (p<0.001). Evaluating a receiver operating characteristic curve (ROC) demonstrated that the cut-off point of endometrial thickness was 10.50 with a sensitivity of 85% and a specificity of 85%.
Conclusion: Determining the cut-off point of 10.50mm for endometrial thickness using transvaginal ultrasound in perimenopausal women is a suitable, non-invasive method, the results of which can predict the results of Pipelle endometrial sampling well.

Keywords

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Journal of Obstetrics, Gynecology and Cancer Research
Volume 3, Issue 2 - Serial Number 9
May and June 2018
Pages 65-71
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History
  • Receive Date: 14 November 2022
  • Revise Date: 18 April 2024
  • Accept Date: 14 November 2022
  • Publish Date: 14 November 2022
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