Authors
1 Lab Medical Sciences Department, Allied Medical Sciences Faculty, Tehran University of Medical Sciences, Tehran, Iran
2 Epidemiology Department, PasteurInstitute, Tehran University of Medical Sciences, Tehran, Iran
3 Management Department, Tehran University of Medical Sciences, Tehran, Iran
4 Obstetrics & Gynecology Department, Tehran University of Medical Sciences, Tehran, Iran
Abstract
Aims: Preterm labors and abortions are among dangers that threaten mothers’ and infants’ lives. Several bacterial, viral, and parasitic agents can cause preterm labor and abortion. Among these bacterial agents, Chlamydia trachomatis plays a very key role. The aim of this study was to detect and isolate Chlamydia trachomatis from urine and its role in preterm labor.
Materials & Methods: This cross sectional study was carried out from 2016 to 2017 in AlMahdi Clinic under the supervision of Tehran University of Medical Sciences. 119 pregnant women who were in the first trimester of pregnancy (between 12 and 14 weeks) referred to a health center for screening tests were selected using available sampling method and were collected their urine samples. The obtained samples were centrifuged and the DNA was extracted from urine sediment. Using specific PCR kits for detecting Chlamydia trachomatis, the presence or absence of this bacteria was investigated in the urine sediment. The data were analyzed using Chi square test.
Findings: The rate of isolating Chlamydia trachomatis from the urine of these pregnant women was 6.72%. There was no significant relationship between chlamydia infection and history of abortion (p=0.93).
Conclusion: The level of the isolation of Chlamydia trachomatis from the urine of pregnant women is twice more than the level of its isolation from samples taken from vaginal and cervical discharge in pregnant women. Therefore, urine is an appropriate sample for the diagnosis of Chlamydia trachomatis since the sampling method is non-invasive and has more positive cases
Keywords
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