Impact of Serum CA19-9 Level in Clinico- Pathological and Radiologic Feature of Mature Cystic Teratoma: A Case Series

Ghasemian Dizajmehr, Sedigheh; Mohammadi Irvanlou, Mahsa; Mohammadi, Afshin; Rashidi Fakari, Farzaneh

Document Type : Case Report Article

Authors

¹ Department of Obstetrics and Gynecology, School of Medicine, Urmia University of Medical Sciences, Urmia, Iran

² Department of Pathology, School of Medicine, Urmia University of Medical Sciences, Urmia, Iran

³ Department of Radiology, School of Medicine, Urmia University of Medical Sciences, Urmia, Iran

⁴ Department of Midwifery, School of Medicine, North Khorasan University of Medical Sciences, Bojnurd, Iran

Abstract

Background & Objective: Ovarian mature cystic teratomas (OMCTS) are one of the most common benign ovarian tumors. Most MCTs can be diagnosed by ultrasonography (us). Due to heterogeneous composition and a variety of appearance, in some non-diagnostic imaging reports it is suggested that we evaluate some tumor markers (CA125 and CA19-9) to complement imaging modalities. According to previous investigation, a single elevated CA 19-9 is in association with specific radio-pathologic features, such as size, torsion, bronchial glands, fat and teeth components. Here we are presenting three different cases of OMCT with different characteristics.
Case Presentation: Case 1: asymptomatic, non-diagnostic US, single- elevated CA19-9, smaller than in 10 cm with bronchial glands and fat component. Case 2: symptomatic, non-diagnostic U.S. normal CA19-9, larger than 10 cm with torsion and necrosis. Case 3: symptomatic, diagnostic US, single- elevated CA19-9, smaller than 10 cm, full of hair and sebaceous material. Computer tomography (CT), in all of our cases was diagnostic based on OMCT. Apologia of pathologic pathway of elevated CA19-9 in both cases 1 and 3 were in agreement with the result of previous investigations. In case 2, despite its large size and torsion, CA 19-9 level was low.
Conclusion: Single- elevated CA 19-9 level in OMCTs could impact benign characteristics of this kind of tumor.

Highlights

✅ Single- elevated CA 19-9 level in OMCTs could impact benign characteristics of this kind of tumor.

Keywords

Main Subjects

Gynecology Oncology

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Journal of Obstetrics, Gynecology and Cancer Research

Impact of Serum CA19-9 Level in Clinico- Pathological and Radiologic Feature of Mature Cystic Teratoma: A Case Series

References

References

Volume 8, Issue 3 - Serial Number 32
May and June 2023
Pages 295-300

Impact of Serum CA19-9 Level in Clinico- Pathological and Radiologic Feature of Mature Cystic Teratoma: A Case Series

References

References

Volume 8, Issue 3 - Serial Number 32May and June 2023Pages 295-300

Volume 8, Issue 3 - Serial Number 32
May and June 2023
Pages 295-300