Document Type : Case Report Article
- Maliheh Arab 1
- Giti Noghabaei 2
- Ghazaleh Fazli 3
- Golnaz Fallah-Talouki 4
- Hamed Tahmasebi 5
- Masoomeh Raoufi 6
- Behnaz Ghavami 7
1 Professor of Gynecology-Oncology, Shahid Beheshti University of Medical Sciences, Tehran, Iran
2 MD, Internist, Imam Hossein hospital, Iran university of medical Sciences
3 MS.c of developmental biology, Science and Research University of Tehran, Tehran, Iran
4 Asistant of Obstetrics & Gynecology,Imam Hossein Medical center ,Shahid Beheshti University of Medical Sciences Tehran,Iran
5 Department of Surgery,Imam Hossein Hospital,Shahid Beheshti University of Medical Sciences,Tehran,Iran
6 Assistant Professor of Radiology, Imam Hossein Medical center ,Shahid Beheshti University of Medical Sciences Tehran,Iran
7 Obstetricion&Gynecologist,Fellowship of Laparoscopy, Tehran University of Medical Sciences Tehran,Iran
Introduction: Low-grade appendiceal mucinous neoplasm (LAMN) is a very rare condition, diagnosed in 0.2-0.7 % of appendectomies. Pathophysiology of the neoplasm involves accumulation of large volume of mucin in appendiceal lumen, resulting in its obstructive dilation. Most epithelial tumors affecting appendix are of the mucinous type and are manifested by mucin accumulation within an inflamed appendix with fibrotic and hyalinized wall.
A 29-year-old female presented with history of chronic and intermittent episodes of abdominal pain and a palpable mass in the right lower abdominal quadrant. Sonography showed a 58 mm mass anterior to the uterus and adjacent to the ovary, probably a uterine myoma. Laparotomy revealed normal uterus, and ovaries with a translucent mass originating from appendix and fixed to cecum. Pathologic examination of the mass was reported as low grade appendiceal mucinous neoplasm.
Conclusion: This is a rare case of appendiceal mucocele in a young female, mimicking pelvic mass, which was misinterpreted by sonography as gynecologic solid mass near uterus. Preoperative diagnosis of appendiceal mucocele is important due to the risk of concurrent GI and ovarian malignancy associated with the condition.
Keywords: Mucocele; Appendix; pseudomyxoma peritonei; low-grade appendiceal mucinous neoplasm