Farname Inc. in collaboration with Iranian Society of Gynecology Oncology

Authors

1 Obstetrician and Gynecologist, Minimally Invasive Surgery Reasearch Center ,Iran University of Medical Sciences , Tehran , Iran,

2 Associate professor in Anesthesiology, Pain Research Center,Anesthesiology department of Iran University of Medical Sciences, Tehran, Iran,

3 Resident of Obstetrics and Gynecology, Iran University of Medical Sciences, Tehran, Iran

Abstract

Background: Hysterectomy is the most common gynecological surgery. Every year, a large number of women around the world undergo this type of surgery for various reasons. Regardless of the type of surgery, bleeding during surgery and after surgery is the most common. Tranexamic acid is a cheap, available and low-complication drug that has been considered in recent years to control bleeding. The present study investigated the effectiveness of Tranexamic acid on the bleeding during laparotomy hysterectomy in women aged 35 to 55 years.
Methods and materials: This study was a randomized, double-blind clinical trial performed on 80 patients undergoing laparotomy hysterectomy. Using a random number table, patients were divided into two groups A (receiving Transid) and the other group receiving drug B (not receiving Transid), both of which received 100 ml of normal saline prepared to reduce bias in the prepared syringe.
Results: Mean age of the patients was 46.24 ± 5.21 years. Based on the results of mean hemoglobin before surgery, the rate of infection, infusion and induction in the control and intervention groups were not statistically different (P> 0.05). Also, the mean of hemoglobin variables before and after, hemorrhage estimated by the surgeon and hemorrhage estimated according to Hernandez formula were not statistically different in the two groups (P> 0.05).
Conclusion: Tranexamic acid administration has no effect on the amount of bleeding during hysterectomy laparotomy.

Keywords

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