Iranian Society of Gynecology Oncology

Document Type : Original Research Article

Authors

1 College of Medical Technology, Medical Lab Techniques, Al-Farahidi University, Baghdad, Iraq

2 College of MLT, Ahl Al Bayt University, Kerbala, Iraq

3 Department of Medical Laboratory Techniques, Al-Mustaqbal University College, Babylon, Iraq

4 Department of Anesthesia Techniques, Al–Nisour University College, Baghdad, Iraq

5 Mazaya University College, Nasiriyah, Iraq

6 Department of Prosthetic Dental Technology, Hilla University College, Babylon, Iraq

7 Department of Dental Industry Techniques, Al-Noor University College, Bartella, Iraq

8 Al-Hadi University College, Baghdad, Iraq

Abstract

Background & Objective: Low and high hemoglobin concentration is one of the main concerns of women during pregnancy due to its high prevalence and adverse effects. The present study aimed to examine the correlation between maternal hemoglobin concentration and the baby's birth weight and height in 326 pregnant women referred to the Alwiyah hospital for obstetrics and gynecology in Baghdad, Iraq, in 2019.
Materials & Methods: In the current descriptive-analytical study, pregnant women were classified into two groups: anemia and normal; four groups of moderate to severe anemia, mild, regular, and high hemoglobin; and eight groups with intervals of 12 g/L from severe anemia to high hemoglobin. This study's variables included infants' age, number of children, education level, socioeconomic status, weight, and height. The data was analyzed using SPSS version 19, descriptive statistics, t-test, and logistic regression. In this study, the level of statistical significance was deemed to be 0.001.
Results: The results showed that the probability of low birth weight and abnormal height increases 4.96 times and 4.13 times, respectively, in mothers with high hemoglobin concentrations versus mothers with low hemoglobin concentrations; these ratios are statistically significant (P<0.001). Also, hemoglobin concentrations ranging from 104 to 115 g/L have the lowest probability. Furthermore, hemoglobin concentrations greater than 125 g/L are statistically significant (P<0.001).
Conclusion: The current study revealed that high maternal hemoglobin concentrations during pregnancy could significantly impact the baby's weight and height.

Highlights

 The current study revealed that high maternal hemoglobin concentrations during pregnancy could significantly impact the baby's weight and height.
 

Keywords

Main Subjects

1. Woldeamanuel GG, Geta TG, Mohammed TP, Shuba MB, Bafa TA. Effect of nutritional status of pregnant women on birth weight of newborns at Butajira Referral Hospital, Butajira, Ethiopia. SAGE Open Med. 2019;7:2050312119827096. [DOI:10.1177/2050312119827096] [PMID] [PMCID]
2. Iftikhar A, Attia Bari FZ, Jabeen U, Masood Q, Waheed A. Maternal anemia and its impact on nutritional status of children under the age of two years. Biomed J. 2018;2(4). [DOI:10.26717/BJSTR.2018.05.001197]
3. Wu W, Lu J, Ruan X, Ma C, Lu W, Luo Y, et al. Maternal essential metals, thyroid hormones, and fetal growth: Association and mediation analyses in Chinese pregnant women. J Trace Elem Med Biol. 2021;68:126809. [DOI:10.1016/j.jtemb.2021.126809] [PMID]
4. Tesema GA, Worku MG, Tessema ZT, Teshale AB, Alem AZ, Yeshaw Y, et al. Prevalence and determinants of severity levels of anemia among children aged 6-59 months in sub-Saharan Africa: A multilevel ordinal logistic regression analysis. PloS One. 2021;16(4):e0249978. [DOI:10.1371/journal.pone.0249978] [PMID] [PMCID]
5. Behaile Teklemariam A, Kelta Wabalo E, Adugna Leta T, Shimeles Assefa S, Chekol Abebe E. Evaluation of Lactate Dehydrogenase and Gamma Glutamyl Transferase Among Pregnant Women with Hypertensive Disorders and Their Association with Disease Severity in Jimma Medical Center, Ethiopia. J Obstet Gynecol Cancer Res. 2022;7(6):497-506. [DOI:10.30699/jogcr.7.6.497]
6. Weze K, Abioye AI, Obiajunwa C, Omotayo M. Spatio-temporal trends in anaemia among pregnant women, adolescents and preschool children in sub-Saharan Africa. Public Health Nutr. 2021;24(12):3648-61. [DOI:10.1017/S1368980020004620] [PMID] [PMCID]
7. Manickavasagam M. Haemoglobin Level of Pregnant Women on First Appointment to Antenatal Care Clinic and Their Awareness on Anemia During Pregnancy. J Obstet Gynecol Cancer Res. 2021;6(2):57-64. https://doi.org/10.30699/jogcr.6.2.57 [DOI:10.30699/jogcr.5.2.57]
8. Subramanian S, Ackerson LK, Smith GD, John NA. Association of maternal height with child mortality, anthropometric failure, and anemia in India. Jama. 2009;301(16):1691-701. [DOI:10.1001/jama.2009.548] [PMID] [PMCID]
9. Perez EM, Hendricks MK, Beard JL, Murray-Kolb LE, Berg A, Tomlinson M, et al. Mother-infant interactions and infant development are altered by maternal iron deficiency anemia. J Nutr. 2005;135(4):850-5. [DOI:10.1093/jn/135.4.850] [PMID]
10. Li H, Xiao J, Liao M, Huang G, Zheng J, Wang H, et al. Anemia prevalence, severity and associated factors among children aged 6-71 months in rural Hunan Province, China: a community-based cross-sectional study. MC public health. 2020;20(1):1-13. [DOI:10.1186/s12889-020-09129-y] [PMID] [PMCID]
11. Karan S, Mathur Y. Risk factors in mothers and newborn. Indian J Pediatr. 1987;54(1):35-40. [DOI:10.1007/BF02751233] [PMID]
12. Gou B-H, Guan H-M, Bi Y-X, Ding B-J. Gestational diabetes: weight gain during pregnancy and its relationship to pregnancy outcomes. Chin Med J. 2019;132(02):154-60. [DOI:10.1097/CM9.0000000000000036] [PMID] [PMCID]
13. Al-Hajjiah NN, Almkhadree MA. The effect of maternal anaemia on the anthropometric measurements in full-term neonates. Asian J Pharm Clin Res. 2018;11(4):3680-1. [DOI:10.22159/ajpcr.2018.v11i4.25579]
14. Singh S, Shrestha S, Marahatta S. Incidence and risk factors of low birth weight babies born in Dhulikhel Hospital. J Inst Med Nepal. 2010;32(3):39-42. [DOI:10.3126/jiom.v32i3.4959]
15. Sun Y, Shen Z, Zhan Y, Wang Y, Ma S, Zhang S, et al. Effects of pre-pregnancy body mass index and gestational weight gain on maternal and infant complications. BMC Pregnancy Childbirth. 2020;20(1):1-13. [DOI:10.1186/s12884-020-03071-y] [PMID] [PMCID]
16. Paulsamy P, Easwaran V, Ashraf R, Alshahrani SH, Venkatesan K, Qureshi AA, et al., editors. Association of Maternal Observation and Motivation (MOM) Program with m-Health Support on Maternal and Newborn Health. Healthcare; 2021. [DOI:10.20944/preprints202111.0028.v1]
17. Kamruzzaman M. Is BMI associated with anemia and hemoglobin level of women and children in Bangladesh: A study with multiple statistical approaches. PloS One. 2021;16(10):e0259116. [DOI:10.1371/journal.pone.0259116] [PMID] [PMCID]
18. Dangour A, Hill H, Ismail SJ. Height, weight and haemoglobin status of 6 to 59-month-old Kazakh children living in Kzyl-Orda region, Kazakhstan. Eur J Clin Nutr. 2002;56(10):1030-8. [DOI:10.1038/sj.ejcn.1601448] [PMID]
19. Hassan JM, Almukhtar SH. Relationship between Birthweight of Newborns and Nutritional status of Pregnant women in Maternal Teaching Hospitals in Mosul City. Pak J Med health Sci. 2022;16(04):840-. [DOI:10.53350/pjmhs22164840]
20. Alemu B, Gashu D. Association of maternal anthropometry, hemoglobin and serum zinc concentration during pregnancy with birth weight. Early Hum Dev. 2020;142:104949. [DOI:10.1016/j.earlhumdev.2019.104949] [PMID]
21. Srour MA, Aqel SS, Srour KM, Younis KR, Samarah F. Prevalence of anemia and iron deficiency among Palestinian pregnant women and its association with pregnancy outcome. Anemia. 2018;2018. [DOI:10.1155/2018/9135625] [PMID] [PMCID]
22. Youssry MA, Radwan AM, Gebreel MA, Patel TA. Prevalence of maternal anemia in pregnancy: the effect of maternal hemoglobin level on pregnancy and neonatal outcome. Opin J Obstet Gynecol. 2018;8(7):676-87. [DOI:10.4236/ojog.2018.87072]
23. Young MF, Oaks BM, Tandon S, Martorell R, Dewey KG, Wendt AS. Maternal hemoglobin concentrations across pregnancy and maternal and child health: a systematic review and meta‐analysis. Ann N Y Acad Sci. 2019;1450(1):47-68. [DOI:10.1111/nyas.14093] [PMID] [PMCID]
24. Carpenter RM, Billah SM, Lyons GR, Siraj MS, Rahman QS, Thorsten V, et al. U-Shaped Association between Maternal Hemoglobin and Low Birth Weight in Rural Bangladesh. Am J Trop Med Hyg. 2022;106(2):424. [DOI:10.4269/ajtmh.21-0268] [PMID] [PMCID]
25. El Foly MA, Abdel-Malek AS, Bebars GM, El-Zaher A, Maha R. Assessment of Cord Blood Hemoglobin and Serum Ferritin Levels in Newborns of Anemic and Non Anemic Mothers in Children and Maternity Minia University Hospital. Mini J Med Res. 2022;31(4):301-9. [DOI:10.21608/mjmr.2022.218145]
26. Dewi NU, Mahmudiono T. Effectiveness of food fortification in improving nutritional status of mothers and children in Indonesia. Int J Environ Res Public Health. 2021;18(4):2133. [DOI:10.3390/ijerph18042133] [PMID] [PMCID]
27. Abioye AI, McDonald EA, Park S, Ripp K, Bennett B, Wu HW, et al. Maternal anemia type during pregnancy is associated with anemia risk among offspring during infancy. Pediatr Res. 2019;86(3):396-402. [DOI:10.1038/s41390-019-0433-5] [PMID] [PMCID]
28. Patel A, Prakash AA, Das PK, Gupta S, Pusdekar YV, Hibberd PL. Maternal anemia and underweight as determinants of pregnancy outcomes: cohort study in eastern rural Maharashtra, India. BMJ Open. 2018;8(8):e021623. [DOI:10.1136/bmjopen-2018-021623] [PMID] [PMCID]
29. Negera A, Sento M. The maternal anthropometry and hemoglobin status in relations to newborn birth weight among primiparous mothers at Adama Hospital Medical College, Eastern Ethiopia: a cross-sectional study. medRxiv. 2022;2022:05.
30. Rahman SM, Siraj MS, Islam MR, Rahman A, Ekström E-C. Association between maternal plasma ferritin level and infants' size at birth: a prospective cohort study in rural Bangladesh. Global Health Action. 2021;14(1):1870421. [DOI:10.1080/16549716.2020.1870421] [PMID] [PMCID]
31. Tiwari P. Relationship between maternal hemoglobin concentration during pregnancy and neonatal birth weight in urban poor community in and around Jamshedpur, Jharkhand, India. Int J Reprod Contracept Obstet Gynecol. 2021;10(10):3828-34. [DOI:10.18203/2320-1770.ijrcog20213845]