Iranian Society of Gynecology Oncology

Document Type : Original Research Article

Authors

1 Department of Obstetrics and Gynecology, Yas Hospital Complex., Tehran University of Medical Sciences, Tehran, Iran

2 Diabetes Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran

3 Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran

4 Department of Obstetrics and Gynecology Department, Zabol University of Medical Sciences, Zabol, Iran

5 Department of Obstetrics and Gynecology, Yas Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran

6 Universal Council of Epidemiology (UCE), Universal Scientific Education and Research Network (USERN), Tehran University of Medical Sciences, Tehran, Iran

Abstract

Background & Objective: Sexual activity is a major determinant of health-related quality of life. The aim of this study was to investigate sexual activity in women with polycystic ovary syndrome.
Materials & Methods: A case control survey was conducted at a tertiary care university hospital (Yas Hospital Complex.). A total of 193 women were enrolled in this study. The Female Sexual Function Index (FSFI) questionnaire was used to assess the sexual dysfunction. In this study, 100 cases with PCOS and 93 healthy controls were studied.
Results: The mean FSFI total score and all domains except orgasm were significantly lower in PCOS patients as compared to healthy controls. With an FSFI score of less than 26.55, sexual dysfunction was found in 62% of PCOS cases versus 18.2% of the control group. Multiple regression analysis showed that FSH and free testosterone were independent predictors of FSFI score. The result showed that more than sixty percent of PCOS women suffer from sexual dysfunction.
Conclusion: PCOS women need to be asked about and managed for sexual dysfunction more frequently than non-PCOS women.

Highlights

 PCOS women need to be asked about and managed for sexual dysfunction more frequently than non-PCOS women.

Keywords

Main Subjects

1. De Niet J, De Koning C, Pastoor H, Duivenvoorden H, Valkenburg O, Ramakers M, et al. Psychological well-being and sexarche in women with polycystic ovary syndrome. Hum Reprod. 2010;25(6):1497-503. [DOI:10.1093/humrep/deq068] [PMID]
2. Bazarganipour F, Ziaei S, Montazeri A, Foroozanfard F, Kazemnejad A, Faghihzadeh S. Sexual functioning among married Iranian women with polycystic ovary syndrome. Int J Fertil Steril. 2014;8(3):273-80.
3. Elkhyat A, Elsokary A, Elshwaikh S. Dose weight gain in lean patients with polycystic ovary syndrome improves ovulation and pregnancy rates? J Obstet Gynecol Cancer Res. 2022;9(1):70-5.
4. Benetti-Pinto CL, Ferreira SR, Antunes Jr A, Yela DA. The influence of body weight on sexual function and quality of life in women with polycystic ovary syndrome. Archi 'Obstet Gynaecol. 2015;291(2):451-5. [DOI:10.1007/s00404-014-3423-1] [PMID]
5. Kocełak P, Chudek J, Naworska B, Bąk-Sosnowska M, Kotlarz B, Mazurek M, et al. Psychological Disturbances and Quality of Life in Obese and Infertile Women and Men. Int J Endocrinol. 2012;2012:236217. [DOI:10.1155/2012/236217] [PMID] [PMCID]
6. Essah PA, Wickham EP, Nestler JE. The metabolic syndrome in polycystic ovary syndrome. Clin Obstet Gynecol. 2007;50(1):205-25. [DOI:10.1097/GRF.0b013e31802f3547] [PMID]
7. Elsenbruch S, Hahn S, Kowalsky D, Öffner AH, Schedlowski M, Mann K, Janssen OE. Quality of life, psychosocial well-being, and sexual satisfaction in women with polycystic ovary syndrome. J Clin Endocrinol Metab. 2003;88(12):5801-7. [DOI:10.1210/jc.2003-030562] [PMID]
8. Kitzinger C, Willmott J. 'The thief of womanhood': women's experience of polycystic ovarian syndrome. Soc Sci Med. 2002;54(3):349-61. [DOI:10.1016/S0277-9536(01)00034-X] [PMID]
9. Hahn S, Janssen OE, Tan S, Pleger K, Mann K, Schedlowski M, et al. Clinical and psychological correlates of quality-of-life in polycystic ovary syndrome. Eur J Endocrinol. 2005;153(6):853-60. [DOI:10.1530/eje.1.02024] [PMID]
10. Stovall DW, Scriver JL, Clayton AH, Williams CD, Pastore LM. Sexual function in women with polycystic ovary syndrome. J Sex Med. 2012;9(1):224-30. [DOI:10.1111/j.1743-6109.2011.02539.x] [PMID] [PMCID]
11. Davari Tanha F, Mohseni M, Ghajarzadeh M. Sexual function in women with primary and secondary infertility in comparison with controls. Int J Impot Res. 2014;26(4):132-4. [DOI:10.1038/ijir.2013.51] [PMID]
12. ESHRE TR, Group A-SPCW. Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome. Fertil Steril. 2004;81(1):19-25. [DOI:10.1016/j.fertnstert.2003.10.004] [PMID]
13. Ferriman D, Gallwey J. Clinical assessment of body hair growth in women. J Clin Endocrinol Metab. 1961;21(11):1440-7. [DOI:10.1210/jcem-21-11-1440] [PMID]
14. Fakhri A, Pakpour AH, Burri A, Morshedi H, Zeidi IM. The Female Sexual Function Index: translation and validation of an Iranian version. J Sex Med. 2012;9(2):514-23. [DOI:10.1111/j.1743-6109.2011.02553.x] [PMID]
15. Eftekhar T, Sohrabvand F, Zabandan N, Shariat M, Haghollahi F, Ghahghaei-Nezamabadi A. Sexual dysfunction in patients with polycystic ovary syndrome and its affected domains. Iran J Reprod Med. 2014;12(8):539-346.
16. Ercan CM, Coksuer H, Aydogan U, Alanbay I, Keskin U, Karasahin KE, Baser I. Sexual dysfunction assessment and hormonal correlations in patients with polycystic ovary syndrome. Int J Impot Res. 2013;25(4):127-32. [DOI:10.1038/ijir.2013.2] [PMID]
17. Mansson M, Norstrom K, Holte J, Landin-Wilhelmsen K, Dahlgren E, Landen M. Sexuality and psychological wellbeing in women with polycystic ovary syndrome compared with healthy controls. Eur J Obstet Gynecol Reprod Biol. 2011;155(2):161-5. [DOI:10.1016/j.ejogrb.2010.12.012] [PMID]
18. Drosdzol A, Skrzypulec V. Quality of life and sexual functioning of Polish infertile couples. Eur J Contracept Reprod Health Care. 2008;13(3):271-81. [DOI:10.1080/13625180802049187] [PMID]
19. Janssen OE, Hahn S, Tan S, Benson S, Elsenbruch S. Mood and sexual function in polycystic ovary syndrome. Semin Reprod Med. 2008;26(1):45-52. [DOI:10.1055/s-2007-992924] [PMID]
20. Coffey S, Bano G, Mason HD. Health-related quality of life in women with polycystic ovary syndrome: a comparison with the general population using the Polycystic Ovary Syndrome Questionnaire (PCOSQ) and the Short Form-36 (SF-36). Gynecol Endocrinol. 2006;22(2):80-6. [DOI:10.1080/09513590600604541] [PMID]
21. Hashemi S, Ramezani Tehrani F, Farahmand M, Bahri Khomami M. Association of PCOS and Its Clinical Signs with Sexual Function among Iranian Women Affected by PCOS. J Sex Med. 2014;11(10):2508-14. [DOI:10.1111/jsm.12627] [PMID]
22. Bancroft J. Sexual effects of androgens in women: some theoretical considerations. Fertil Steril. 2002;77:55-9. [DOI:10.1016/S0015-0282(02)02961-8] [PMID]