Iranian Society of Gynecology Oncology

Document Type : Original Research Article

Authors

1 Department of Obstetrics and Gynecology, Oncology fellowship, Clinical Research Development Unit, Kowsar Hospital, Qazvin University of Medical Sciences, Qazvin, Iran.

2 Department of Anesthesiology, Clinical Research Development Unit, Kowsar Hospital, School of Medicine, Qazvin University of Medical Sciences, Qazvin, Iran.

3 Department of Obstetrics and Gynecology, Infertility fellowship, Clinical Research Development Unit, Kowsar Hospital, Qazvin University of Medical Sciences, Qazvin, Iran.

4 4. Department of Obstetrics and Gynecology, Clinical Research Development Unit, Kowsar Hospital, School of Medicine, Qazvin University of Medical Sciences, Qazvin, Iran.

5 5. Department of nursing, Clinical Research Development Unit, Kowsar Hospital, School of nursing and midwifery, Qazvin University of Medical Sciences, Qazvin, Iran.

6 Researcher, Qazvin University of Medical Sciences, Qazvin, Iran.

Abstract

Background: Cooling the uterus during cesarean section has emerged as one of the non-pharmacological management for blood loss during cesarean section. The aim of this study was to evaluate the effect of uterine cooling during the cesarean section on decreasing postpartum hemorrhage.

Methods: In this single-blinded randomized clinical trial, a sample of 300 women with a singleton pregnancy, at 37 to 40 weeks gestation, who were scheduled for cesarean section was divided into two groups of 150 participants. In the intervention group after placental delivery, the uterus was covered with cold saline-soaked surgical sponges at 0-4°C at the time of hysterotomy repair, and the control group received standard cesarean section. The volume of blood loss, the hemoglobin level before surgery and 24 h after surgery, the need for additional oxytocic therapy, and the incidence of adverse effects were recorded.

Results: The bleeding volume and hemoglobin concentration reduction were significantly lower in the intervention group than in the control group (260.86± 150.25 Vs 214.35± 83.51, P<0.0001 and 1.24±0.75 Vs 1.54±0.92, P = 0.007 respectively). There were no statistically significant differences between the two groups in the frequency of need for additional uterotonic drugs. (18% vs. 21.33%, P = 0.475.)

Conclusion: The use of uterine cooling during cesarean section reduced the volume of blood loss and the rate of decline in hemoglobin concentration.

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