Iranian Society of Gynecology Oncology

Document Type : Original Research Article


1 1 Infertility Fellowship, Infectious and Tropical Diseases Research Center of Zahedan University of Medical Sciences

2 Endometriosis Research Center, Iran University of Medical Sciences, Tehran, Iran

3 Assistant professor of community medicine, Department of Community Medicine, School of Medicine, Zahedan University of Medical Sciences. Zahedan, Iran

4 Assistant Professor of Pathology, Department of Pathology, School of Medicine, Zahedan University of Medical Sciences

5 Finetech in Medicine Reaearch Center, Iran University of Medical Sciences, Tehran, Iran

6 General Physician, Zahedan University of Medical Sciences


Background & Objective: Endometrial hyperplasia is the primary precursor of endometrial cancer in the female reproductive system, with abnormal uterine bleeding (AUB) being the predominant manifestation of this condition. The purpose of this study was to determine the prevalence of endometrial hyperplasia and its correlation with various factors among patients presenting with abnormal uterine bleeding.
Materials & Methods: This cross-sectional descriptive-analytical study reviewed the hospital records of all patients with abnormal uterine bleeding admitted to Ali Ebn-e Abi Taleb Hospital in Zahedan from April 2015 to April 2018. Data were analyzed using the SPSS.
Results: The prevalence of endometrial hyperplasia was estimated to be 20.3%. The average age of the study subjects was about 45 years. The highest number of patients (37, 52.9%) belonged to the age group of 36-50 years. Among the different types of endometrial hyperplasia observed, the most common was "simple non-atypical hyperplasia" found in 45 patients (64.3%), while the least common was "simple atypical hyperplasia" observed in three patients (4.3%). Overall, "non-atypical hyperplasia" (including both simple and complex types) was present in 58 patients (82.85%). The prevalence of infertility, obesity, hypertension, diabetes, premature menarche, late menopause, family history, oligomenorrhea, and polycystic ovary syndrome (PCOS) was reported in 7.1%, 32.9%, 24.3%, 22.9%, 8.5%, 13.6%, 7.1%, 5.7%, and 3.4% of cases, respectively.
Conclusion: women with a history of diabetes, hypertension, and obesity are at an increased risk of developing endometrial hyperplasia. Therefore, it is crucial to evaluate these patients for the presence of endometrial hyperplasia.


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