Aim: To evaluate changes in serum AMH levels, fertility and metabolic conditions in reproductive-age severely obese women, after bariatric surgery.
Design: prospective cohort study.
Methods: This study had been conducted on marked obese women who were referred to BS in Tanta university hospital. the AMH and other hormones (FSH- LH- free Testosterone- SHBG- fasting Insulin) levels had been measured as part of their evaluation will be reviewed before and after (6) months the surgery. The involved women were in reproductive age between 18 and 40 years old. With BMI > 36 kg/m2 and < 42 kg/m2.
Results: From 64 female who had been enrolled, 50 patients only completed the 6 months follow up , and it was found there was a significant difference as regard the weight and the BMI , fasting insulin level and regular menstrual pattern after 6 month follow but other fertility factors including were improved but had no significant difference .
Also 20 cases (40%) had a spontaneous ovulation after 6 moth follow up after BS , and by comparing them to those who had no spontaneous ovulation ,there was a significant effect on weight reduction on occurrence of spontaneous ovulation , BMI parameter, and the level of change of BMI, regular menstrual cycle, while the other fertility related parameters although improved but failed to show any significant relationship .
Conclusion: BS and reduction of the weight had a positive effect on the reproductive performance of obese female.