Iranian Society of Gynecology Oncology

Document Type : Original Research Article


Obstetric and Gynecological Department, Medical college/Al-Qadisiyah University


The aims of current study Comparison of the effectiveness of intravenous iron sucrose versus oral ferrous fumarate during pregnancy.

Material and Method in this study, Pregnant women with iron deficiency anaemia were treated with either intravenous ferrous sucrose or oral ferrous fumarate, and their effectiveness, safety, and tolerability were evaluated. Formerly patients were allocated or divided into two groups as following Group 1(Oral group) Group 2 (Intravenous group). Randomization in choosing. In each group, 50 patients were assessed. For four weeks, the patients in the oral group received two ferrous fumarate pills, each of which enclosed Iron elemental 100 mg. This treatment involved taking 5 mg of folic acid each day. The intravenous group got 100 ml of 0.9% NaCl containing a dose of iron sucrose dissolved in it and calculated by a specific equation. After four weeks, serum ferritin levels were assessed as the trial's main endpoint.

Result comparison hemoglobin level produce a substantial pre- and post-treatment difference (P=0.000**). While when comparison before treatment of two group 1&2 showed non-significant differences (P=0.376). When comparison post treatment of two groups found a significant difference in each group (P= 0.000**). Current study demonstrated the percentage change % of hemoglobin level between groups. Serum Ferritin Level harvest significant difference pre and post treatment (P=0.000**).

Conclusion: Maternal iron reserves are more effectively increased by intravenous ferrous sucrose than by oral ferrous fumarate 200 mg/day.


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