Document Type : Original Research Article
Authors
- Ali D. Marhash 1
- Mohammed S. Abdul-Razaq 1
- Milal Muhammad AL-Jeborry 2
- Wisam Jasim 3
- Safa Khaleel khalaf 3
1 Babylon Institute, Al-Furat Al-Awsat Technical University, Baghdad, Iraq
2 Department of Obstetrics and Gynecology, College of Medicine. Babylon University, Baghdad, Iraq
3 Central Public Health Laboratory, Baghdad, Iraq
Abstract
Background and objective: Worldwide, cervical cancer stands as the leading cause of cancer-related fatalities. Cervical cancer is unequivocally attributed to the human papillomavirus (HPV) infection, which is both essential and adequate for its development. The particular prevalence of HPV in the population of Iraq is currently unclear. The objective of this study is to determine the frequency of HPV and identify the most common genotypes present in a sample of the Iraqi population.
Materials and Methods: From November 2022 to December 2023, a total of 300 women with cervical anomalies, who were referred to the Gynecological Oncology Departments in multiple hospitals in Babylon and Baghdad, had cervical swabs collected. Real-time polymerase chain reaction was utilized to conduct HPV DNA testing on all specimens.
Result: A total of 300 women between the ages of 20 and 60 were screened during the collecting period. The average age was 30 years. The prevalence of High-risk HPV was 16.7% overall. The age group of women between 30 and 40 years exhibited the highest overall prevalence of HPV. Our population survey indicates a higher prevalence of genotyping for HPV 16, 18, and 31.
Conclusion: In this work, we used multiplex real-time pcr. This approach has numerous advantages, including HPV detection and genotyping to known prevalent genotypes as well as cost effective and no time consuming.
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