Maternal Fetal Medicine
Mohaddeseh Ghazi; Ashraf Jamal; Vajiheh Marsosi; Laleh Eslamian; Maryam noorzadeh; Mahsa Naemi; Mamak Shariat; Paria Boustani
Articles in Press, Accepted Manuscript, Available Online from 26 April 2024
Abstract
Background: Prenatal invasive procedures are used for diagnostic and therapeutic purposes. The present study aimed to assess the indications and early complications of invasive diagnostic tests.Materials and Methods: This retrospective descriptive study was conducted on 708 pregnant women who were referred ...
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Background: Prenatal invasive procedures are used for diagnostic and therapeutic purposes. The present study aimed to assess the indications and early complications of invasive diagnostic tests.Materials and Methods: This retrospective descriptive study was conducted on 708 pregnant women who were referred for prenatal invasive tests in Tehran, Iran from May 2018-to April 2022. All medical records of the participants were reviewed and entered into the study. According to the implemented procedures, medical records were categorized into two chorionic villus sampling (CVS) and amniocentesis groups. The primary outcome was determining the frequent indications of invasive diagnostic tests and post-procedure complications. Results: Six hundred and sixty-eight medical records were included. Amniocentesis procedure was performed for 624 (93.7%) and 44 cases (6.3%) underwent CVS. The most frequent indication for invasive prenatal procedures was a history of abnormal findings related to the first trimester biomarkers followed by the abnormal findings of the second trimester biochemical markers, a history of high nuchal translucency>99th percentile, and abnormal biomarkers of sequential test. Comparing post-procedure complications, the results showed no significant difference between the CVS and amniocentesis groups (P=0.845). In the amniocentesis group, 2 cases had shown spontaneous abortion and 3 leakage of amniotic fluid, as well as two cases in the CVS group, had reported vaginal bleeding. Conclusion: Our results delineated that positive fetal aneuploidy screening tests together with increased nuchal translucency were the main indications of the invasive prenatal tests. Amniotic fluid leakage, vaginal bleeding, and spontaneous abortion should be considered as procedure-related complications.
Maternal Fetal Medicine
Adibeh Mauwloudi; Laleh Eslamian; Vajiheh Marsousi; Ashraf Jamal; Maryam Noorzadeh; Mahsa Naemi; Ali Reza Norouzi; Nazila Mesbah
Volume 9, Issue 1 , January and February 2024, , Pages 1-6
Abstract
Background & Objective: The aim of this study was to determine which of the two drugs of ibuprofen, as a common non-steroidal anti-inflammatory drugs (NSAID), and acetaminophen would have the least effect on postpartum hypertension in patients with preeclampsia.Materials & Methods: Clinicodemographic ...
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Background & Objective: The aim of this study was to determine which of the two drugs of ibuprofen, as a common non-steroidal anti-inflammatory drugs (NSAID), and acetaminophen would have the least effect on postpartum hypertension in patients with preeclampsia.Materials & Methods: Clinicodemographic data including age, gestational age at delivery, body mass index, parity, and route of delivery, were collected through interviews with patients and reviewing patient records. In this double-blind clinical trial, among 84 patients included in the study, 42 patients were randomly assigned to the acetaminophen (650 mg every 6 to 24 hours) and 42 patients into the ibuprofen (600 mg every 6 to 24 hours) group.Results: The two groups were not significantly different in terms of mean age (P = 0.322), body mass index (P = 0.950), route of delivery (P = 0.657), parity (P = 0.818), and mean systolic (p = 0.530) and diastolic blood pressure (P = 0.691). Following the intervention, the duration of blood pressure control (P = 0.182), mean systolic blood pressure (P = 0.371), and mean diastolic blood pressure (P = 0.13) were not significantly different in the acetaminophen and ibuprofen groups. There was no significant difference between the two groups in terms of the number of patients and the dosage of opioids used.Conclusion: The results revealed that in patients with preeclampsia, acetaminophen and ibuprofen to control postpartum pain have a similar impact on blood pressure.
