Iranian Society of Gynecology Oncology
Obstetrics and Gynecology
Comparison of Vaginal Misoprostol Alone versus a Combination of Vaginal Misoprostol and Intracervical Foley Catheter for Inducing Labor

Sara A. Al-Rawaf; Enas T Mousa

Volume 9, Issue 1 , January and February 2024, , Pages 88-94

  Introduction: Inducing labor is a common practice in obstetrics to prevent maternal and fetal complications. There are several methods of labor induction, including pharmacological and mechanical approaches. The objective of this study was to determine the most effective approach for labor induction.Method: ...  Read More

Obstetrics and Gynecology
Adjuvant Intravenous Tranexamic Acid Increases the Efficacy of Sublingual Misoprostol Compared with Carbetocin to Reduce the Amount of Blood loss During Cesarean Delivery: A Randomized Clinical Trial

Nahla W. Shady; Amed A. Taha; Hany F. Sallam

Volume 8, Issue 6 , November and December 2023, , Pages 579-586

  Background & Objective: To determine the safety and adequacy of intravenous (IV) carbetocin compared to IV tranexamic acid (TA) plus sublingual misoprostol in reducing hemorrhage during and following cesarean delivery (CD) in women with at least one risk factor for postpartum hemorrhage.Materials ...  Read More

Obstetrics and Gynecology
E Cervical ripening: Intravaginal Misoprostol in Compare to Intracervical Foley Single Balloon Catheter, A Randomized Clinical Trial

maryam dehghan; tajosadat alameh; Zahra Allameh; zahra Seyed-Hoseini

Volume 8, Issue 2 , March and April 2023, , Pages 113-119

  Background & Objective: The aim of this study was to compare the efficacy of vaginal misoprostol with Foley balloon catheter for cervical ripening in women with singleton pregnancies and an unfavorable cervix.Materials & Methods: Eighty pregnant women with unfavorable cervix were randomly ...  Read More

Obstetrics and Gynecology
Malignant Hyperthermia, Cardiac Dysrhythmia and Hypertension Crisis in Sublingual Misoprostol: Educational Policy for Adverse Drug Reaction Organization

Mohammad Reza Zeraati; Hojjat Torkmandi; Mohammad Abdi; Mohammad Reza Jamshidi; Alireza Safaie

Volume 8, Issue 1 , January and February 2023, , Pages 86-94

  Pyrexia and shivering are the most popular side effects of postpartum administration of misoprostol, but other side effects of this drug are very rare. A 27-year-old pregnant female patient was admitted to Ayatollah Mousavi hospital (Zanjan, Iran), complaining about severe headache and the primary diagnosis ...  Read More

Obstetrics and Gynecology
Misoprostol for Cervical Ripening Prior to Molar Evacuation: A letter to the editor

Reda Hemida

Volume 7, Issue 4 , March and April 2022, , Pages 356-357

  Dear Editor- in –Chief of Journal of Obstetrics, Gynecology and Cancer Research (JOGCR),I write to you regarding the published article in The Journal of Obstetrics, Gynecology, and Oncology research titled “The Association of Gestational Trophoblastic Neoplasia and Misoprostol Administered ...  Read More

Obstetrics and Gynecology
Response letter to Professor Hemida regarding a published article with the doi of

Soheila Aminimoghaddam

Volume 7, Issue 4 , March and April 2022, , Pages 358-360

  Response to the editor letter Dear Professor Behtash,I am writing this letter to respond to the letter written by Professor Reda Hemida from Mansoura University, Egypt, regarding a publication of mine titled “The Association of Gestational Trophoblastic Neoplasia and Misoprostol Administered ...  Read More

Obstetrics and Gynecology
Uterine Rupture in Second Trimester Due to Misoprostol Use: A Case Report and Literature Review

Fatemeh Keikha; Mahshid Shooshtari; Narges Zamani

Volume 7, Issue 3 , January and February 2022, , Pages 243-246

  Intravaginal misoprostol is used worldwide with excellent results for second-trimester pregnancy termination. However, it has a rare but serious complication of uterine rupture, both in previously scarred and unscarred uteri. In this report, we present a case of this rare complication in an unscarred ...  Read More

Obstetrics and Gynecology
Comparison of Estradiol and Misoprostol in Transformation Zone Visibility in Colposcopy

Mitra Modares Gilani; Fariba Yarandi; Narges Zamani; Shaghayegh Nowroozi; Sara Ramhormozian; Elham Shirali

Volume 7, Issue 2 , September and October 2021, , Pages 77-82

  Background & Objective: Estradiol and misoprostol have been used for the enhancement of transformation zone (TZ) visibility in vaginal colposcopy. However, no consensus has been reached on the superiority of one medication over the other. This study aimed to compare the efficacy of estradiol and ...  Read More

Obstetrics and Gynecology
Lessons Learnt from Cases of Misoprostol-Based Pregnancy Termination Followed by Uterine Rupture: Report of 3 Cases

Fatemeh Golshahi; Fariba Yarandi; Sara Ramhormozian; Elham Shirali

Volume 7, Issue 2 , September and October 2021, , Pages 121-125

  With increase in the second-trimester pregnancy termination, debates continue on the most suitable mode of termination. Misoprostol is used as an agent for the medical abortion. Some authors believe that uterine rupture risk as a complication of medical termination is higher in the patients with positive ...  Read More

Obstetrics and Gynecology
Comparing Two Methods of Rectal Diclofenac Administration for Pain Management in Second Trimester Abortion: A Randomized Clinical Trial

Mahboobeh Shirazi; Mehnoosh Torkzaban; Samira Fallah; Marjan Ghaemi

Volume 7, Issue 1 , September and October 2021, , Pages 20-24

  Background and Objective: Pain is the most common side effect of induced medical abortion. However, the optimal analgesia method remains as a clinical challenge. This study aimed to compare the efficacy of two methods of administration of diclofenac as a prophylactic or a therapeutic in pain management ...  Read More

General Gynecology and Pelvic Floor
Evening Primrose versus Misoprostol for Cervical Dilatation before Gynecologic Surgeries; a Double–blind Randomized Clinical Trial

Behnaz Nouri; Ahmad Reza Baghestani; Paricheher Pooransari

Volume 6, Issue 2 , March 2021, , Pages 87-94

  Backround and Objective: Cervical ripening/dilatation is necessary for gynecologic procedures, but pharmacological dilators have several adverse effects. In this regard, evening primrose oil (EPO) has been shown as an effective dilator, though it has few complications. This randomized clinical trial ...  Read More

Obstetrics and Gynecology
The Effect of Various Dosages of Misoprostol for Cervical Preparation Before the Hysteroscopy

Mehrnaz Valadan; Mohadeseh Mojarad; Elham Feizabad

Volume 5, Issue 3 , November 2020, , Pages 88-92

  Background & Objective: Hysteroscopy is an impressive  diagnostic and therapeutic procedure for uterine cavity abnormalities. There are several methods for cervical preparation prior to hysteroscopy, among which misoprostol (a prostaglandin E1 analog) is the most common. However, misoprostol ...  Read More

Contrastive Analysis of Vaginal Misoprostol and Foley Catheter in Cervical Ripening and Labor Induction

Shapoor Shoja; Seyedeh Reyhaneh Yousefi Sharami; Shole Shahgheibi; Farnaz Zand-Vakili; Shamsi Zare; Daem Roshani; Nasrin Sofizadeh

Volume 4, Issue 3 , September and October 2019, , Pages 105-110

  Background & Objective: The induction of labor is needed to terminate pregnancy in pregnant women lacking labor pain. Common indications of labor induction include rapture of membranes without labor pain, hypertension, fetus’ unreassuring conditions and post-term pregnancies. The purpose of ...  Read More

The Association of Gestational Trophoblastic Neoplasia and Misoprostol Administered Before Suction Curettage of Molar Pregnancy

Soheila Aminimoghaddam; Afsar Ahmad; Setare Nassiri

Volume 4, Issue 3 , September and October 2019, , Pages 111-116

  Background & Objective: Gestational trophoblastic neoplasia contains a group of abnormal trophoblastic tumors including hydatidiform moles (partial and complete) and non-molar trophoblastic neoplasms (invasive mole, choriocarcinoma, placental site trophoblastic tumor). The incidence is 1-2 per 1000 ...  Read More

The Effect of a Single Preoperative Dose of Sublingual Misoprostol in Reducing Intraoperative Blood Loss after Total Abdominal Hysterectomy: A Single-Blind Randomized Controlled Trial

Shayesteh Parashi; Vahideh Astaraei; Mansoureh Vahdat; Parisa Dini; Mahdis Mohammadianamiri

Volume 3, Issue 4 , November and December 2018, , Pages 143-147

  Background & Objective: Postoperative hemorrhage is one of the most frequently cited complications of total abdominal hysterectomy (TAH). This study aimed to investigate the effect of a single preoperative dose of sublingual misoprostol on reducing blood loss during total abdominal hysterectomies. Materials ...  Read More

Comparison of Using Misoprostol with or without Letrozole in Abortion Induction: A Placebo-Controlled Clinical Trial

Forough Javanmanesh; Maryam Kashanian; Sara Mirpang

Volume 3, Issue 2 , May and June 2018, , Pages 49-52

  Aims: The rate of induced abortion is growing worldwide. In this study, we aimed at comparing using misoprostol with or without Letrozole in abortion. Materials and Methods: In this placebo-controlled trial, 46 women with a gestational age of fewer than 20 weeks, who were candidates of legal abortion, ...  Read More

The Effect of Vaginal pH on the Efficacy of Vaginal Misoprostol for the Induction of Midtrimester Pregnancy Termination

Mansooreh Zanjani; Jalil Kohpayeh; Zhila Karimi

Volume 2, Issue 1 , March and April 2017

  Background: Vaginal misoprostol is said to dissolve better in an acidic environment, thus, in this study we aimed to evaluate the influence of increasing vaginal acidity on the effectiveness of vaginal misoprostol for the induction of midtrimester pregnancy using acidic environment. Methods: A total ...  Read More

Trends in Techniques of Abortion in Iran from 1994 to 2014

Masoumeh Fallahian; Shahrzad Tavana

Volume 1, Issue 1 , May and June 2016

  Abortion is desperately selected by some females who cannot continue their unintended pregnancies in all societies, some will suffer complications and some will die. Annual number of induced abortion has increased in the developing countries but the maternal death related to unsafe abortion has declined ...  Read More