Gynecology Oncology
Afsaneh Tehranian; Akram Ghahghaei-Nezamabadi; Maryam Motiei Langeroudi; Reyhaneh Aghajani
Volume 8, Issue 1 , January and February 2023, , Pages 53-56
Abstract
Background & Objective: We compared two different methods of visual inspection of the cervix, including Visual inspection of the cervix with acetic acid (VIA) and Visual inspection of the cervix with Lugol's iodine (VILI) in terms of sensitivity and specificity in diagnosis of pre-malignant cervical ...
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Background & Objective: We compared two different methods of visual inspection of the cervix, including Visual inspection of the cervix with acetic acid (VIA) and Visual inspection of the cervix with Lugol's iodine (VILI) in terms of sensitivity and specificity in diagnosis of pre-malignant cervical lesions in comparison to colposcopy guided biopsy.Materials & Methods: In this cross-sectional study, a total number of 200 women who were referred to the colposcopy clinic of Arash women’s hospital (Tehran, Iran) for cervical cancer screening, underwent VIA, VILI, and colposcopy guided biopsy during 2018-2019.Results: The calculated sensitivity and specificity of VIA and VILI in this population were (100% and 69.5%) and (100% and 60%), respectively, whereas the sensitivity and specificity of both VIA and VILI tests in combination were 100% and 77.2%. The positive and negative predictive values were 32.7% and 100%, respectively, when combined form of VIA and VILI was applied in this population.Conclusion: VIA and VILI alone or in combination could be used as screening tests to evaluate the presence of cervical cancer and in case of positive results, supplementary tests such as colposcopy guided biopsy could be performed for definite diagnosis.
Gynecology Oncology
Seyyed Mohammad Tabatabaei; Moslem Taheri Soodejani; Hamid Reza Shoraka; Marzieh Mahmoudimanesh; Saeid Eslami; Azimeh Ghaderi
Volume 7, Issue 3 , January and February 2022, , Pages 200-205
Abstract
Background and Objective: Breast cancer is a malignant lesion caused by abnormal changes and growth in breast tissue epithelial cells, including glands, lobules, and larynx. Therefore, the current study's objective was to estimate the incidence of breast and cervical intraepithelial lesions in Iran. ...
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Background and Objective: Breast cancer is a malignant lesion caused by abnormal changes and growth in breast tissue epithelial cells, including glands, lobules, and larynx. Therefore, the current study's objective was to estimate the incidence of breast and cervical intraepithelial lesions in Iran. This study is based on results from a screening program implemented in the province of Isfahan, Iran.Methods: Two stages of cancer screening were performed in the study on over 250000 women in 2018.Results: As a result of this study, it was determined that in 2018, there was an incidence of 422 benign breast tumors per 100 000 women (95% CI: 393-450). Also, the incidence of breast cancer was 65 (95% CI: 54-76) per 100 000 women, and that of Cervical intraepithelial lesions was 45 (95% CI: 27-63) per 100 000 women in 2018.Conclusion: This study revealed that breast cancer and cervical intraepithelial lesions are increasing in Isfahan province. Moreover, it was found that screening for these 2 cancers leads to early detection of patients, which results in early treatment and an increase in the 5-year survival rate in these patients.
General surgery
Atefeh Moridi; Sudabeh Mahmoodi; Nayereh Rahmati; Marzieh Fathi; Zahra Naeiji
Volume 6, Issue 4 , August 2021, , Pages 188-194
Abstract
Background & Objective: Awareness of breast cancer risk factors, clinical presentations and screening rules and methods may encourage women to use preventive measures more commonly. Materials & Methods: A total of 691 women from general population were interviewed using a standardized ...
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Background & Objective: Awareness of breast cancer risk factors, clinical presentations and screening rules and methods may encourage women to use preventive measures more commonly. Materials & Methods: A total of 691 women from general population were interviewed using a standardized questionnaire. Demographic data, level of awareness about risk factors, presentations and screening the breast cancer and their general perception about the treatment’s efficacy were evaluated.Results: Of the participants, 45.7% had “good” knowledge about the presentations of breast cancer while the level of awareness was “good” in 19.2% of them in field of risk factors (statistically significant difference). As only about 16% of them knew that women should perform breast self-examination once a month and about 15% of them were aware of the screening role of the annual clinician performed breast examination.Conclusion: Most of our participants had statistically significant lower level of knowledge about the risk factors and screening rules and tools of breast cancer than its clinical presentation.
Mahboobeh Shirazi; Soheila Sarmadi; Shirin Niromanesh; Fatemeh Rahimi Sharbaf; Behrokh Sahebdel; Fatemeh Golshahi; Leila Asadi; Maedeh Rahmanzadeh
Volume 4, Issue 1 , March and April 2019, , Pages 12-15
Abstract
Background & Objective: Diagnosing fetal disorders and abnormalities in the early stages of pregnancy can prevent future adverse conditions for the infant and his/her family. This study aimed to evaluate the sensitivity and specificity of the first- and second-trimester screening tests for identifying ...
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Background & Objective: Diagnosing fetal disorders and abnormalities in the early stages of pregnancy can prevent future adverse conditions for the infant and his/her family. This study aimed to evaluate the sensitivity and specificity of the first- and second-trimester screening tests for identifying fetal chromosomal disorders in pregnant women.
Materials & Methods: A total of 960 pregnant women participated in this retrospective cohort study that was performed at Yas Hospital. The participants’ mean age was 31.07±0.17 years. In the present study, all pregnant women, who referred to Yas Hospital for their first- and second-trimester screening tests, were studied from 2015 to 2017.
Results: Most of the participants (43.4%) were primigravida. The sensitivity of the first-trimester screening test was 70%, and its specificity was 80.3%. The sensitivity and specificity of the second-trimester screening test were 45% and 94.5%, respectively.
Conclusion: Despite recent advances in the prenatal field, the accuracy of screening tests may still vary depending on maternal age and other existing characteristics. Consequently, in parents consulting, the possibility of false positives and negatives should be considered in the tests.
Mojgan Karimi Zarchi; Soraya Teimoori
Volume 2, Issue 4 , November and December 2017, , Pages 1-2
