General Gynecology and Pelvic Floor
Shams Anmar Burhan; Raed Ghazi Reshan; Abdelaziz El Refaeey; Amoura M. Abou-El-Naga
Volume 9, Issue 2 , March and April 2024, , Pages 218-224
Abstract
Background & Objective: The presence of anesthetic drugs in the serum with potential negative effects on hormone concentration and pregnancy rate has been shown in a number of human research. To assess the effects on blood hormone concentration and pregnancy rate of two different medications (remifentanil ...
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Background & Objective: The presence of anesthetic drugs in the serum with potential negative effects on hormone concentration and pregnancy rate has been shown in a number of human research. To assess the effects on blood hormone concentration and pregnancy rate of two different medications (remifentanil vs. fentanyl) used for general anesthesia during oocyte retrieval.
Materials & Methods: the present prospective comparative study was conducted at Iraq's "High Institute of Infertility Diagnosis and Assisted Reproductive Technologies/Al-Nahrain University/Baghdad/Iraq" infertility center and was approved by Mansoura University for its validity. Sixty infertile women who were having (ICSI) for a range of infertility-related reasons that entered the study. The women's ages varied from 20 to 45 years. The study's length was extended from September 2022 to September 2023. According to the general anesthetic protocol for oocyte retrieval, those patients were divided into two groups. Midazolam, propofol, and fentanyl were given to the group one, while remifentanil, midazolam, and propofol were given to the group two.
Results: Compare the hormone levels before and after fentanyl anesthesia. The current study's findings indicated that remifentanil led to a greater pregnancy rate (40.0%) than fentanyl (36.7%). According to the results, there were significantly higher LH levels after fentanyl anesthesia (P = 0.014). However, insignificantly higher FSH (P = 0.481) and prolactin (P = 0.076) levels post-fentanyl anesthesia. Also, significantly higher LH levels after remifentanil anesthesia (P = 0.046), insignificantly higher FSH levels (P = 0.383) and prolactin levels (P = 0.16) after remifentanil anesthesia. In the fentanyl group, the recovery time was substantially longer (P<0.001).
Conclusion: Because of its quicker recovery time and much greater pregnancy rate, remifentanil is preferred over fentanyl in normal general anesthetic treatments for egg harvest in ICSI operations.
Babak Hosseinzadeh Zorofchi; Elahe Jahan; Setare Nassiri; Atosa Najmodin; Elham Saffarieh
Volume 3, Issue 2 , May and June 2018, , Pages 73-77
Abstract
Aims: Owing to the effects of anesthesia on pain after hysterectomy as well as different advantages and disadvantages of spinal anesthesia (SA) and general anesthesia (GA), giving priority to one of these techniques over the other still seems controversial. The aim of the present study was to compare ...
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Aims: Owing to the effects of anesthesia on pain after hysterectomy as well as different advantages and disadvantages of spinal anesthesia (SA) and general anesthesia (GA), giving priority to one of these techniques over the other still seems controversial. The aim of the present study was to compare SA with GA in terms of pain intensity, the frequency of nausea and vomiting and morphine requirements after abdominal hysterectomy.
Instruments and Methods: This double-blind clinical trial was conducted on 40 abdominal hysterectomy candidates with American Society of Anesthesiologists I and II presenting to Kowsar Hospital, Semnan, Iran, in 2015. All the patients were briefed on the pain assessment scale the day before the surgery, randomly divided into two groups of GA and SA and underwent abdominal hysterectomy using the same technique. Postoperative pain was then recorded upon admission to post-anesthesia care unit and 6 and 12h later. Furthermore, frequency of nausea and vomiting as well as intravenous morphine requirements was recorded within the first 12h after the surgery. Data were analyzed using independent t-test and Chi-square by SPSS 16 software.
Findings: Postoperative pain was found to be significantly lower upon entering PACU and 6 and 12h later in the SA group compared to that in the GA group, as was the case for the frequency of nausea and vomiting as well as the dose of intramuscular morphine (p<0.05).
Conclusion: Generally, postoperative pain in SA is lower than in GA, although different postoperative complications such as nausea and vomiting are observed.
