Department of Obstetrics and Gynecology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
Department of Radiology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
Department of Pathology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
Introduction: In patients with female genital tract cancers, during treatment, diﬀerentiating between a tumor recurrence and a benign phenomenon is of great importance. This study aimed to report a case of retroperitoneal lymphocele in a patient with primary ovarian cancer.
Case Presentation: A 49-year-old woman diagnosed with papillary serous ovarian carcinoma was referred to the oncology clinic in 2017. She was treated with an optimal surgical staging and underwent adjuvant chemotherapy. After 3 courses of chemotherapy, she complained of a large abdominal mass in the umbilical area. Evaluating the mass conﬁrmed retroperitoneal lymphocele, which was treated with a non-surgical therapy.
Conclusions: Pelvic mass in patients with previous ovarian cancer is not necessarily due to the recurrence of the tumor and the possibility of lymphocele diagnosis should be considered. Since preventing the causes of lymphocele is very diﬃcult, it is only necessary to carefully follow-up and provide essential consultations for high risk patients.
- Zikan M, Fischerova D, Pinkavova I, Slama J, Weinberger V, Dusek L, et al. A prospective study examining the incidence of asymptomatic and symptomatic lymphoceles following lymphadenectomy in patients with gynecological cancer. Gynecol Oncol. 2015;137(2):291-8. [DOI:10.1016/j.ygyno.2015.02.016] [PMID]
- Minig L, Patrono MG, Cardenas-Rebollo JM, Martin Marﬁl P, Rodriguez-Tabares V, Chuang L. Use of TachoSil(R) to Prevent Symptomatic Lymphocele after an Aggressive Tumor Debulking with Lymphadenectomy for Advanced Stage Ovarian Cancer. A Pilot Study. Gynecol Obstet Invest. 2016;81(6):497-503. [DOI:10.1159/000443640] [PMID]
- Pastore M, Manci N, Marchetti C, Esposito F, Iuliano M, Manganaro L, et al. Late aortic lymphocele and residual ovary syndrome after gynecological surgery. World J Surg Oncol. 2007;5:146. [DOI:10.1186/1477-7819-5-146] [PMID]
- Gauthier T, Uzan C, Lefeuvre D, Kane A, Canlorbe G, Deschamps F, et al. Lymphocele and ovarian cancer: risk factors and impact on survival. Oncologist. 2012;17(9):1198-203. [DOI:10.1634/theoncologist.2012-0088] [PMID]
- Radosa MP, Diebolder H, Camara O, Mothes A, Anschuetz J, Runnebaum IB. Laparoscopic lymphocele fenestration in gynaecological cancer patients after retroperitoneal lymph node dissection as a ﬁrst-line treatment option. BJOG. 2013;120(5):628-36. [DOI:10.1111/1471-0528.12103] [PMID]
- Goes Junior AM, Jeha SA. Idiopathic lymphocele: a possible diagnosis for infraclavicular masses. Case Rep Surg. 2012;2012:593028. [DOI:10.1155/2012/593028] [PMID]
- Buda A, Ghelardi A, Fruscio R, Guelﬁ F, La Manna M, Dell'Orto F, et al. The contribution of a collagenbrin patch (Tachosil) to prevent the postoperative lymphatic complications after groin lymphadenectomy: a double institution observational study. Eur J Obstet Gynecol Reprod Biol. 2016;197:156-8. [DOI:10.1016/j.ejogrb.2015.12.005] [PMID]
- Tinelli A, Mynbaev OA, Tsin DA, Giorda G, Malvasi A, Guido M, et al. Lymphocele prevention after pelvic laparoscopic lymphadenectomy by a collagen patch coated with human coagulation factors: a matched case-control study. Int J Gynecol Cancer. 2013;23(5):956-63. [DOI:10.1097/IGC.0b013e31828eeea4] [PMID]
- Achouri A, Huchon C, Bats AS, Bensaid C, Nos C, Lecuru F. Complications of lymphadenectomy for gynecologic cancer. Eur J Surg Oncol. 2013;39(1):81-6. [DOI:10.1016/j.ejso.2012.10.011] [PMID]
- Kim HY, Kim JW, Kim SH, Kim YT, Kim JH. An analysis of the risk factors and management of lymphocele after pelvic lymphadenectomy in patients with gynecologic malignancies. Cancer Res Treat. 2004;36(6):377-83. [DOI:10.4143/crt.2004.36.6.377] [PMID]
- Kohler C, Kyeyamwa S, Marnitz S, Tsunoda A, Vercelino F, Schneider A, et al. Prevention of lymphoceles using FloSeal and CoSeal after laparoscopic lymphadenectomy in patients with gynecologic malignancies. J Minim Invasive Gynecol. 2015;22(3):451-5. [DOI:10.1016/j.jmig.2014.12.007] [PMID]
- Buda A, Fruscio R, Pirovano C, Signorelli M, Betti M, Milani R. The use of TachoSil for the prevention of postoperative complications after groin dissection in cases of gynecologic malignancy. Int J Gynaecol Obstet. 2012;117(3):217-9. [DOI:10.1016/j.ijgo.2011.12.021] [PMID]
- Gallotta V, Fanfani F, Rossitto C, Vizzielli G, Testa A, Scambia G, et al. A randomized study comparing the use of the Ligaclip with bipolar energy to prevent lymphocele during laparoscopic pelvic lymphadenectomy for gynecologic cancer. Am J Obstet Gynecol. 2010;203(5):483. [DOI:10.1016/j.ajog.2010.06.053] [PMID]