Comparative Study Between Superficial and Deep Myometrial Invasion in Endometrial Cancer Type 1 in Relation to Regional Lymph Nodes Metastasis

El Sokkary, Hossam Hassan Aly Hassan

doi:10.30699/jogcr.8.4.357

Document Type : Original Research Article

Author

Hossam Hassan Aly Hassan El Sokkary

Department of Obstetrics and Gynecology, School of Medicine, Alexandria University, Alexandria, Egypt

https://doi.org/10.30699/jogcr.8.4.357

Abstract

Background & Objective: The present study compares between superficial and deep myometrial invasion in type 1 endometrial cancer in relation to regional lymph nodes metastasis, so we can answer the question to do or not do lymphadenectomy, this life-threatening procedure in both superficial and deep myometrial invasion with type 1, clinically and radiologically stage 1 endometrial cancer.
Materials & Methods: Patients were divided into 2 groups distributed as follows: group I includes 50 patients type 1 endometrial cancer with superficial myometrial invasion and group II includes 50 patients type 1 endometrial cancer with deep myometrial invasion. Total abdominal hysterectomy with bilateral salpingo-opherectomy with pelvic and lower para-aortic lymphadenectomy to all patients included in the study from both groups. Histopathological examinations were done to all the specimen from both groups to confirm diagnosis of type 1 endometrial cancer, depth of myometrial invasion, pathological grading and metastasis to the regional lymph nodes.
Results: Considering regional lymph nodes metastasis in both groups, there is a statistical difference between group I and group II in relation to regional lymph nodes metastasis as group II (cases with deep myometrial invasion) are associated with more regional lymph nodes metastasis (P= 0.0001)).
Conclusion: Deep myometrial invasion in type 1 endometrial cancer is associated with significant increase in regional lymph nodes metastases.

Highlights

✅ Deep myometrial invasion in type 1 endometrial cancer is associated with significant increase in regional lymph nodes metastases.

Keywords

Main Subjects

Gynecology Oncology

References

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Journal of Obstetrics, Gynecology and Cancer Research

Comparative Study Between Superficial and Deep Myometrial Invasion in Endometrial Cancer Type 1 in Relation to Regional Lymph Nodes Metastasis

References

References

Volume 8, Issue 4 - Serial Number 33
July and August 2023
Pages 357-365

Comparative Study Between Superficial and Deep Myometrial Invasion in Endometrial Cancer Type 1 in Relation to Regional Lymph Nodes Metastasis

References

References

Volume 8, Issue 4 - Serial Number 33July and August 2023Pages 357-365

Volume 8, Issue 4 - Serial Number 33
July and August 2023
Pages 357-365