Gynecology Oncology
Hemant Kumar Sharma
Volume 6, Issue 4 , August 2021, , Pages 224-227
Abstract
Malignant pericardial effusion presenting with cardiac tamponade is a rare manifestation of metastatic gynecological cancer. Our patient, a 62-year-old female was presented with papillary serous adenocarcinoma of the right ovary in 2016. She was treated with interval cytoreduction surgery and platinum-based ...
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Malignant pericardial effusion presenting with cardiac tamponade is a rare manifestation of metastatic gynecological cancer. Our patient, a 62-year-old female was presented with papillary serous adenocarcinoma of the right ovary in 2016. She was treated with interval cytoreduction surgery and platinum-based chemotherapy until 2018. Now, she presented with sudden onset dyspnea, tachypnea, tachycardia with hypotension, and distended jugular venous pressure. Echocardiography confirmed a large pericardial effusion with mild bilateral pleural effusion. She underwent an emergent pericardiocentesis which yielded 350 mL of hemorrhagic fluid and cytological examination of smears confirmed the presence of metastatic adenocarcinoma cells. The patient was managed conservatively and discharged after one week of hospitalization with a referral to the oncology center for further treatment. With increasing longevity and improved chemotherapeutic regimens, cases of malignant pericardial effusion with cardiac tamponade are on the rise, and therefore, clinicians need to be familiar with the prompt diagnosis and management of this life-threatening disease process.
Elham Shirali; Fariba Yarandi; Nadereh Behtash; Omid Hemmatian
Volume 3, Issue 2 , May and June 2018, , Pages 87-91
Abstract
Aims: Cervical cancer is one of the most common cancer in the female since 1990. Neoadjuvant chemotherapy (NACT) uses before surgery, especially in countries with limited radiotherapy facilities. The aim of the present review was to study the effect of NACT before radical surgery in comparison with other ...
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Aims: Cervical cancer is one of the most common cancer in the female since 1990. Neoadjuvant chemotherapy (NACT) uses before surgery, especially in countries with limited radiotherapy facilities. The aim of the present review was to study the effect of NACT before radical surgery in comparison with other treatments and various clinical outcomes.
Information and Methods: This study is a systematic review and includes previous publishes about cervical cancer and effect of NACT before radical surgery. Over 40 previous studies were reviewed, none of them was case report, at least 5 studies were randomized clinical trials and 6 of them were meta-analysis or systematic review.
Findings: NACT before surgery demonstrates advantages to reduce the rate of lymph node metastasis and parametrial infiltration, so improves progression-free survival in patients with pelvic lymph node invasion (Approximately 35% of stage IB2–IIB bulky). NACT also decreases tumor volume and minimizes the need for adjuvant radiotherapy, thus NACT under consideration of quality of life and cost-effectiveness should be recommended. NACT is really effective in decreasing incidence of pathological risk factors.
Conclusion: NACT response associated with the stage of diagnosis, tumor size and pathology of the specimen (Squamous tumor has a better response than a non-squamous tumor). NACT seems to be feasible in the management of stage IB bulky cervical cancer, NACT followed by surgery represent an alternative to primary chemoradiotherapy in young and sexually active patients.
Leila Pirzade; Setare Nassiri; Mohammad Reza Vakili; Maryam Ameri
Volume 3, Issue 1 , March and April 2018, , Pages 45-48
Abstract
Introduction: Bartholin gland primary cancer occurs scarcely. Adenoid cystic carcinoma of the Bartholin gland is one of the rarest types of primary adenocarcinoma. Treatment delayed can lead to high rate of local recurrence and distant metastasis. The aim of this experimental case study was to discuss ...
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Introduction: Bartholin gland primary cancer occurs scarcely. Adenoid cystic carcinoma of the Bartholin gland is one of the rarest types of primary adenocarcinoma. Treatment delayed can lead to high rate of local recurrence and distant metastasis. The aim of this experimental case study was to discuss a woman with misdiagnosed and mistreated ACC-BG, as a benign situation.
Patient Information: In this experimental case study, a 54-year-old woman referred to Joint Committee in Gynecology Oncology Department of Imam Khomeini Hospital of Tehran University of Medical Sciences, Tehran, Iran on Aug 2016 with a large mass within her vaginal distal wall. This woman was undertaken marsupialization for Bartholin cyst. Because of the bizarre manifestation of intervention, the biopsy was performed and revealed as adenoid cystic carcinoma of the Bartholin gland. Therefore, wide local excision and ipsilateral inguinal lymphadenectomy were considered. Adjuvant irradiation was planned. nificant difference in glucose levels in the first and second fingertip blood drops (p=0.257), while there was a significant difference between glucose levels in the first and second fingertip blood drops with standard venous sample (p<0.05). There was also a significant correlation between 2 drops in expression of glucometry results.
Conclusion: Adenoid cystic carcinoma of the Bartholin gland is very rare, but despite its low prevalence, it should be considered especially in the older patient or when the Bartholin cyst is unusually large and sticking to the surrounding tissue to prevent delays in diagnosis and treatment
Setare Nasiri; Shahrzad Sheikh Hasani; Azamosadat Mousavi; Mitra Modarres Gilani; Setare Akhavan; Mohammad Rahim Rahim Vakili
Volume 1, Issue 3 , November and December 2016
Abstract
Introduction: Mesonephric adenocarcinoma of uterine cervix is a rare variant of primary endocervical adenocarcinoma and a few cases have been reported previously. In fact in non-metastatic adenocarcinoma of the cervix, less than 5% possess mesonephric type. Because of the low incidence of mesonephric ...
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Introduction: Mesonephric adenocarcinoma of uterine cervix is a rare variant of primary endocervical adenocarcinoma and a few cases have been reported previously. In fact in non-metastatic adenocarcinoma of the cervix, less than 5% possess mesonephric type. Because of the low incidence of mesonephric adenocarcinoma, various methods have been proposed for treatment of mesonephric adenocarcinoma. Nevertheless, there is no unity in treatment approaches.
Case Presentation: Here, we present a 45-year woman who had bloody discharge for 6 months period. Hormonal profile such as thyroid stimulating hormon (TSH) and prolactin was normal and all imaging studies showed a cervical fibroma as a mass. Abdominal hysterectomy -bilateral salpingectomy was performed. After pathologic report as a mesonephric adenocarcinoma, she received radiation and then she was candidate for bilateral oophorectomy.
Conclusions: Because of the diversity and an unusual appearance of mesonephric adenocarcinoma with aproblematic case of cervical mass, it is very important to consider mesonephric adenocarcinoma as a type of diagnosis. Numerous differential diagnoses should be considered for management of this type of carcinoma. In order to make a diagnosis, deep biopsy of infiltrative mass of uterine cervix, is mandatory.
