Sedigheh Borna; Nasim Khorami; Azin Ghamari; Fahimeh Ghotbizadeh Vahdani
Volume 4, Issue 1 , March and April 2019, , Pages 24-28
Abstract
Background & Objective: This prospective study aimed to determine the relationship between maternal and amniotic fluid (AF) lipid profiles in the second trimester with pregnancy outcomes.
Materials & Methods: One hundred-eighty singleton pregnant women, with a gestational age of 16-22 weeks, ...
Read More
Background & Objective: This prospective study aimed to determine the relationship between maternal and amniotic fluid (AF) lipid profiles in the second trimester with pregnancy outcomes.
Materials & Methods: One hundred-eighty singleton pregnant women, with a gestational age of 16-22 weeks, were enrolled in this study. All women underwent amniocentesis, and 2 mL of AF was investigated for AF lipid profile. Furthermore, the serum maternal lipid profile was evaluated simultaneously. All participants were followed up until the delivery, and postnatal outcomes were recorded.
Results: Mean maternal age and body mass index (BMI) of all participants were 5.8±33 years and 25.6±2.8 kg/m2, respectively. Mean maternal estriol, cholesterol, and triglyceride levels, as well as mean cholesterol and triglyceride levels of AF, were significantly different between term and preterm; intrauterine growth retardation (IUGR) and non-intrauterine growth retardation (non-IUGR); and low birth weight and normal weight neonates (P < /em><0.001). The AF cholesterol level was an independent predictor of term or preterm delivery, while the maternal estriol level was an independent predictor of IUGR or normal growth.
Conclusion: Maternal and amniotic fluid lipid profiles could be good indicatives of fetus growth.
Bouhlol Ghorbanian; Yousef Saberi
Volume 2, Issue 2 , May and June 2017
Abstract
Background: Atherogenic indices are among risk factors of diabetes which can cause cardiovascular diseases. The purpose of this study was to examine the effect of a 10-week aerobic training on atherogenic indices, lipid profile, and body composition in women with type II diabetes.
Methods: In this ...
Read More
Background: Atherogenic indices are among risk factors of diabetes which can cause cardiovascular diseases. The purpose of this study was to examine the effect of a 10-week aerobic training on atherogenic indices, lipid profile, and body composition in women with type II diabetes.
Methods: In this quasi-experimental study, 40 postmenopausal women with type II diabetes (aged 40 to 60 years) were selected using convenience sampling method and were randomly assigned to experimental (n = 20) and control (n = 20) groups. The exercise protocol included a 10-week aerobic training [aerobic exercise and walking for 3d/wk, 45 to 60 min/d with 45 to 60% heart rate reserve (HRR)]. The atherogenic indices of non-HDL cholesterol (non-HDL-c), atherogenic index of plasma (AIP), low-density lipoprotein cholesterol to high-density lipoprotein ratio (LDL-c/HDL-c ratio), total cholesterol to high-density lipoprotein ratio (TC/HDL-c), lipid product index (LPA), lipid profile, and body composition were measured before and after the intervention. The obtained data were analyzed using t-test. The statistical significance criterion was set at P < 0.05.
Results: The results showed that the levels of TG, LDL-c/HDL-c, and TC/HDL-c significantly decreased as a result of the intervention. However, the changes of LPA, AIP, HDL-c, LDL-c, TC, non-HDL-c, and body composition indices were not significant.
Conclusions: Considering the results of the current study, it seems that aerobic exercise and walking with appropriate volume and intensity can affect atherogenic indices, lipid profile, and body composition in diabetic patients and can reduce the risk of cardiovascular diseases, especially atherosclerosis, among these patients. Further studies are needed to achieve more accurate results.
