Gynecology Oncology
Isha Nandal; Roopa Malik; Krishna Dahiya
Volume 8, Issue 6 , November and December 2023, , Pages 633-636
Abstract
Primary fallopian tube carcinoma is a very rare gynecological malignancy and poses a challenge in diagnosis preoperatively. We are reporting a rare case of bilateral primary fallopian tube carcinoma in a 48-year-old lady with classical symptoms. These symptoms are seen in less than 15% of cases. The ...
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Primary fallopian tube carcinoma is a very rare gynecological malignancy and poses a challenge in diagnosis preoperatively. We are reporting a rare case of bilateral primary fallopian tube carcinoma in a 48-year-old lady with classical symptoms. These symptoms are seen in less than 15% of cases. The differential diagnosis for bilateral fallopian tube cancer includes secondary malignancies arising from endometrial, ovarian and gastrointestinal cancers. Although the prognosis is poor. Early diagnosis, optimum cytoreduction and adjuvant chemotherapy are important to improve survival in such patients.
Obstetrics and Gynecology
Ashwaq Kadhim Mohammed; Vian Hussam Almansi Alqani; Zainab Muayad Essa
Articles in Press, Accepted Manuscript, Available Online from 09 March 2024
Abstract
Background: An unusual manifestation of prenatal trophoblastic illness is a twin molar pregnancy with a live foetus and a hydatidiform mole. Due to increased ovulation stimulation, this unusual scenario is rising. Most hydatidiform moles are complete with a foetus, while 0.005 to 0.01% of gestations ...
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Background: An unusual manifestation of prenatal trophoblastic illness is a twin molar pregnancy with a live foetus and a hydatidiform mole. Due to increased ovulation stimulation, this unusual scenario is rising. Most hydatidiform moles are complete with a foetus, while 0.005 to 0.01% of gestations have a partial mole. This report examined the clinical appearance and outcome of live foetuses with molar pregnancies. Methods: This study was done at Adiwaniyah, where the Maternity and Pediatrics Teaching Hospital has one obstetrics centre. The researcher reviewed 20 years of obstetric reports and found 12 cases of hydatiform mole pregnancies with ultrasound reports and/or post-partum examination of the product of gestation indicating twin pregnancy with a single viable foetus. Results: The average age was 27.00 ±6.87 years, with a range of 18-37 years. The parity breakdown was 8 (66.7%) primiparous and 4 (33.3%) multiparous. The average gestational age upon diagnosis was 19.50 ±3.09 weeks, ranging from 15 to 25 weeks. The average gestational age at delivery commencement was 26.67 ±7.09 weeks, with a range of 17-35 weeks. Seven (58.3%) amniocentesis were normal. Maternal complications included bleeding, anemia, blood transfusion, threatening miscarriage, and pre-eclampsia. End-of-gestation outcomes comprised 5 (41.7%) living and healthy newborns and 3 (25.0%) dead babies. There were 5 (41.7%) men and 2 (16.7%) women. Also reported: miscarriage, premature labour, and caesarean sections. Conclusion: Twin pregnancy with a live viable foetus and a molar pregnancy is rare, hence early detection and care are crucial to prevent difficulties for the mother and foetus.
Pathology
Amal Abd El hafez
Volume 8, Issue 1 , January and February 2023, , Pages 81-85
Abstract
Plasma cell myeloma (PCM) of the breast is extremely unusual. It probably constitutes 0.7% of extramedullary plasmacytomas, and 0.2% of all breast malignancies. Clinically and radiologically, PCM of the breast is indistinguishable from breast carcinoma or other primary breast disorders. Therefore, histomorphological ...
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Plasma cell myeloma (PCM) of the breast is extremely unusual. It probably constitutes 0.7% of extramedullary plasmacytomas, and 0.2% of all breast malignancies. Clinically and radiologically, PCM of the breast is indistinguishable from breast carcinoma or other primary breast disorders. Therefore, histomorphological examination with immunohistochemistry are considered as gold standards for its diagnosis in tissue samples. We report a case of a 30-year-old female presented with a progressive huge ulcerating left breast mass, despite chemotherapy. She had a history of an initially misdiagnosed humeral lytic lesion, and recurrent lytic boney lesions for the past 7 years. Positive CD138, CD56 and Kappa immunostaining has confirmed PC differentiation and monoclonality of the tumor cells. Subsequently, PCM of breast was diagnosed and the patient was transferred for chemotherapy and follow-up.
Obstetrics and Gynecology
Minoo Yaghmaei; Ladan Ajori; Mojgan Mokhtari
Volume 9, Issue 1 , January and February 2024, , Pages 95-101
Abstract
Background & Objective: Although the safety of cesarean sections has increased, there are still considerations, especially for women with a history of repeated cesarean sections. This study was conducted with the aim of investigating maternal and neonatal outcomes in candidates for cesarean ...
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Background & Objective: Although the safety of cesarean sections has increased, there are still considerations, especially for women with a history of repeated cesarean sections. This study was conducted with the aim of investigating maternal and neonatal outcomes in candidates for cesarean sections due to repeat cesarean sections according to the number of previous cesarean sections.Materials & Methods: This prospective descriptive study was conducted from April 2020 to June 2022 at Taleghani Hospital. All candidates for cesarean sections due to repeated cesarean sections were included in the study. According to the number of previous cesarean sections, they were divided into three groups. Statistical analysis was performed with Kruskal-Wallis, Chi-squared and Fisher’s exact tests. A P value < 0.05 indicated statistical significance.Results: A total of 345 women were included in the study. The results of this study showed that these three groups were significantly different in terms of duration of surgery (P<0.001), abnormal placental adhesion (0.012), and the presence of intraperitoneal adhesions (P<0.001), but there was not a significant difference in terms of other maternal and neonatal outcomes (P<0.05).Conclusion: The results of this study showed that an increase in the number of previous cesarean sections does not increase most maternal and neonatal complications during a current cesarean section. Of course, it should be noted that the number of women with a history of three or more previous cesarean sections was small in this study, and for this reason, more studies are needed.
Pathology
Nahid Ghanbarzadeh; Ali Nadjfai-Semnani; Mohammad Nadjafi-Semnani; Mahmoodreza Behravan; Majid Zare-Bidaki
Volume 8, Issue 2 , March and April 2023, , Pages 184-187
Abstract
Echinococcus granulosus (sensu lato) is the main cause of Cystic hydatid in human and livestock in the world and is considered a neglected tropical disease. Hydatid cysts often form in the liver (50–70%) and less frequently the lung, spleen, kidney, bone, brain and genital system. Ovarian hydatid ...
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Echinococcus granulosus (sensu lato) is the main cause of Cystic hydatid in human and livestock in the world and is considered a neglected tropical disease. Hydatid cysts often form in the liver (50–70%) and less frequently the lung, spleen, kidney, bone, brain and genital system. Ovarian hydatid cyst is one of the rarest cases with nonspecific clinical presentation. Here in a case report study, we report a primary unilateral ovarian hydatid cyst in a 45-years-old woman. This patient was presented with a large pelvic mass. A pelvic multiloculated mass in abdominal ultrasound and a solid-cystic lesion of the left adnexa in CT scan were reported. All other laboratory tests and chest X-ray showed typical results. Molecular method was performed to confirm radiography and staining methods. A cystic mass on the left fallopian tube and ovary was found in the patient's laparotomy and all were resected with the appearance of a tubo-ovarian abscess. Postoperative pathological and molecular diagnosis confirmed a hydatid cyst disease. Five years of follow-up revealed no recurrence of the disease. Hydatid cyst can.
General Gynecology and Pelvic Floor
Shams Anmar Burhan; Raed Ghazi Reshan; Abdelaziz El Refaeey; Amoura M. Abou-El-Naga
Volume 9, Issue 2 , March and April 2024, , Pages 218-224
Abstract
Background & Objective: The presence of anesthetic drugs in the serum with potential negative effects on hormone concentration and pregnancy rate has been shown in a number of human research. To assess the effects on blood hormone concentration and pregnancy rate of two different medications (remifentanil ...
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Background & Objective: The presence of anesthetic drugs in the serum with potential negative effects on hormone concentration and pregnancy rate has been shown in a number of human research. To assess the effects on blood hormone concentration and pregnancy rate of two different medications (remifentanil vs. fentanyl) used for general anesthesia during oocyte retrieval.
Materials & Methods: the present prospective comparative study was conducted at Iraq's "High Institute of Infertility Diagnosis and Assisted Reproductive Technologies/Al-Nahrain University/Baghdad/Iraq" infertility center and was approved by Mansoura University for its validity. Sixty infertile women who were having (ICSI) for a range of infertility-related reasons that entered the study. The women's ages varied from 20 to 45 years. The study's length was extended from September 2022 to September 2023. According to the general anesthetic protocol for oocyte retrieval, those patients were divided into two groups. Midazolam, propofol, and fentanyl were given to the group one, while remifentanil, midazolam, and propofol were given to the group two.
Results: Compare the hormone levels before and after fentanyl anesthesia. The current study's findings indicated that remifentanil led to a greater pregnancy rate (40.0%) than fentanyl (36.7%). According to the results, there were significantly higher LH levels after fentanyl anesthesia (P = 0.014). However, insignificantly higher FSH (P = 0.481) and prolactin (P = 0.076) levels post-fentanyl anesthesia. Also, significantly higher LH levels after remifentanil anesthesia (P = 0.046), insignificantly higher FSH levels (P = 0.383) and prolactin levels (P = 0.16) after remifentanil anesthesia. In the fentanyl group, the recovery time was substantially longer (P<0.001).
Conclusion: Because of its quicker recovery time and much greater pregnancy rate, remifentanil is preferred over fentanyl in normal general anesthetic treatments for egg harvest in ICSI operations.
Obstetrics and Gynecology
Esmat Barooti; Farzaneh Rashidi Fakari; Soodabeh Darvish; Narges Tavakoly
Volume 7, Issue 3 , January and February 2022, , Pages 226-229
Abstract
Background & Objective: In pregnancy, the serum level of cancer antigen-125 (CA-125) increases in the first trimester and abortion. However, different studies reported conflicting results about the use of serum CA-125 to determine the prognosis of threatened abortion. In the present study, we try ...
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Background & Objective: In pregnancy, the serum level of cancer antigen-125 (CA-125) increases in the first trimester and abortion. However, different studies reported conflicting results about the use of serum CA-125 to determine the prognosis of threatened abortion. In the present study, we try to determine if the measurement of CA-125 level could be used as a predictor of outcome in women with threatened abortion.Materials & Methods: This prospective case-control study was performed on 58 patients with threatened abortion and 58 healthy pregnant women with a gestational age of fewer than 20 weeks (as the control group). In both groups, serum CA-125 level was measured. The patients were followed to determine who completed the pregnancy period and who eventually miscarried. Finally, the levels of CA-125 in these groups were compared.Results: The mean age of patients was 28.47 and 27.84 in the case and control groups, respectively; there was no significant statistical difference between the two groups (95% CI: -1.94 to 3.18, P < /em>=0.632). Also, there was no significant difference between them for BMI (95% CI: -1.09 to 1.38, P < /em>=0.813), gestational age (95% CI: -1.31 to 1.04, P < /em>=0.816), and parity (P < /em>=0.51). The mean serum level of CA-125 in the control group was 22.51 ± 6.82 IU/mL, and in the threatened abortion group was 27.70 ± 7.50 IU/mL. This difference was statistically significant (P<0.001). Of the patients, 51.72% with threatened abortion continued their pregnancy, and 48.28% eventually miscarried. The mean serum levels of CA-125 were 25.30±6.63 IU/mL and 30.28±7.63 IU/ml in patients who continued the pregnancy and miscarried, respectively (P < /em>=0.01).Conclusion: A single measurement of the maternal CA-125 may be used as an available, inexpensive prognostic test to determine the outcome of threatened abortion. However, a small number of patients is the main limitation of the present study. More studies with a larger sample size are required to accept the role of maternal CA-125 in predicting the outcome of threatened miscarriage.
Gynecology Oncology
Giti Noghabaei; Maliheh Arab; Ghazaleh Fazli; Golnaz Fallah-Talouki; Masoomeh Raoufi; Hamed Tahmasebi; Behnaz Ghavami
Volume 8, Issue 3 , May and June 2023, , Pages 301-305
Abstract
Background & Objective: Low-grade appendiceal mucinous neoplasm (LAMN) is a very rare condition, diagnosed in 0.2-0.7% of appendectomies. The pathophysiology of the neoplasm involves accumulation of large volume of mucin in the appendiceal lumen, resulting in its obstructive dilation. Most epithelial ...
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Background & Objective: Low-grade appendiceal mucinous neoplasm (LAMN) is a very rare condition, diagnosed in 0.2-0.7% of appendectomies. The pathophysiology of the neoplasm involves accumulation of large volume of mucin in the appendiceal lumen, resulting in its obstructive dilation. Most epithelial tumors affecting the appendix are of the mucinous type and are manifested by mucin accumulation within an inflamed appendix with fibrotic and hyalinized wall.Case Presentation: A 29-year-old female presented with a history of chronic and intermittent episodes of abdominal pain and a palpable mass in the right lower abdominal quadrant. Sonography showed a 58 mm mass anterior to the uterus and adjacent to the ovary, probably a uterine myoma. Laparotomy revealed normal uterus, and ovaries with a translucent mass originating from the appendix and fixed to the cecum. Pathologic examination of the mass was reported as low grade appendiceal mucinous neoplasm.Conclusion: This is a rare case of appendiceal mucocele in a young female, mimicking a pelvic mass, which was misinterpreted by sonography as a gynecologic solid mass near the uterus. Preoperative diagnosis of appendiceal mucocele is important due to the risk of concurrent GI and ovarian malignancy associated with the condition.
General Gynecology and Pelvic Floor
Sarah Lotfi; Abbas Ahmadi
Volume 7, Issue 4 , March and April 2022, , Pages 354-355
Abstract
Infertility is the failure of the male or female reproductive system to conceive after 12 months or more of regular unprotected sexual intercourse (1). Failure to ovulate, problems in the menstrual cycle, infections, inadequate egg maturation, ejaculation problems, antibodies that attack sperm and tumors ...
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Infertility is the failure of the male or female reproductive system to conceive after 12 months or more of regular unprotected sexual intercourse (1). Failure to ovulate, problems in the menstrual cycle, infections, inadequate egg maturation, ejaculation problems, antibodies that attack sperm and tumors are some of the reasons that can make a man or a woman infertile. COVID-19 is a disease caused by a new type of coronavirus; it is an infectious disease caused by the acute respiratory syndrome of coronavirus 2 (SARS-CoV-2).This article is about the fact that patients with COVID-19 are more prone to infertility than other normal people. There is a possibility that this coronavirus could have a pathophysiological effect on the testes. Additional data have shown that active COVID-19 infection significantly reduces the ratio of testosterone to LH, showing a significant effect on the response of Leydig cells to LH stimulation (2). Men are said to be more likely to get COVID-19 than women; even the mortality rate is higher (3). The testes can be a potential target for the SARS-CoV-2 virus, and testicular damage and subsequent infertility after COVID-19 infection can be explained theoretically (4). It was only in May that six semen samples were positive for SARS-CoV-2 (5).
Gynecology Oncology
Ghodratolah Maddah; Mohammad Ali Mohammadzadeh Rezae; Zohreh Yousefi; Helena Azimi; Leila Mousavi Seresht
Volume 8, Issue 4 , July and August 2023, , Pages 411-416
Abstract
Background & Objective: Pelvic exenteration and other types of super-radical procedures are the standard of care in the management of patients with recurrent or persistent cervical cancer. But, since the extent of surgery and possible morbidities are considered as an important challenge in low-resource ...
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Background & Objective: Pelvic exenteration and other types of super-radical procedures are the standard of care in the management of patients with recurrent or persistent cervical cancer. But, since the extent of surgery and possible morbidities are considered as an important challenge in low-resource countries, there is need to investigate the outcomes of similar patient.Materials & Methods: The present study tries to report the successful outcome of radical surgery in detailed in 7 cases in a low-economic setting.Results: Total Pelvic exenteration was performed in three but free margin could be achieved by less radical approach in others. All were alive up to 5yaers of follow-up.Conclusion: What we had noticed was the excellent survival prognosis even in curative intent. It is highly recommended, considering the psychological effect of such an extensive surgery and quality of life in these patients with advanced disease and loss of hope.
Obstetrics and Gynecology
Marzieh Talebian; Niloofar Mehri; Maryam Mousavi Shirazi
Volume 7, Issue 5 , July and August 2022, , Pages 462-465
Abstract
Severe injury to the nervous system in pregnancy needs advanced critical care support to the mother and consideration of fetal effects. Managing persistent vegetative state (PSV) cases in pregnant patients is complex due to the lack of clear guidelines for medical and ethical reasons. This reports a ...
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Severe injury to the nervous system in pregnancy needs advanced critical care support to the mother and consideration of fetal effects. Managing persistent vegetative state (PSV) cases in pregnant patients is complex due to the lack of clear guidelines for medical and ethical reasons. This reports a gravida 4, maternal persistent vegetative state case due to a car accident for a 25-year-old woman at 20 pregnancy weeks. Aggressive support enabled the continuation of pregnancy toward 3th trimester without any impediment to the infant's development. A fetal scan for growth monitoring showed an estimated fetal weight near the 75th centile. Intervention in the pregnancy of a patient suffering PSV is not required if both mother and fetus are stable. Maternal malnutrition may adversely affect the fetus and neonate. In this case, high caloric nutrition with partial parenteral nutrition was employed. We monitored both the mother and her child in an attempt to gather data pertinent to the appropriate care of pregnancy in a persistent vegetative state and the potential sequel for offspring.
Obstetrics and Gynecology
Rakhmanova Nodira Khodjayazovna; Thaiba Abdulrazzaq; Mazin A. A. Najm; Sadiq M. Al-shaikh; Khulood Majid Alsaraf; Mariam Alaa Toama; Mahmood Hasen Shuhata Alubiady; Shaymaa Abdulhameed Khudair
Volume 8, Issue 5 , September and October 2023, , Pages 520-527
Abstract
Background & Objective: One of the most prevalent musculoskeletal issues during pregnancy is pelvic pain, which most pregnant women may experience to varying degrees. The current research aims to identify and evaluate the risk factors contributing to pelvic pain in pregnant women.Materials & ...
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Background & Objective: One of the most prevalent musculoskeletal issues during pregnancy is pelvic pain, which most pregnant women may experience to varying degrees. The current research aims to identify and evaluate the risk factors contributing to pelvic pain in pregnant women.Materials & Methods: The present case-control research was conducted on 180 pregnant women at Baghdad's Alwiyah Hospital for Obstetrics and Gynecology in 2022. For data collection, two questionnaires and a checklist were utilized. The questionnaires included demographic information about women and questions about risk factors, and the checklist included the results of women's examinations to identify risk factors. Using SPSS.23 software, the data were analyzed, and the statistical significance level of the results was considered less than 0.05.Results: The results showed that from the demographic variables, only the age variable showed a statistically significant difference between the two groups (P<0.05). Also, evaluating the risk factors indicated a significant difference between the two groups for the baby's weight, back pain before pregnancy, and back pain in the previous pregnancy (P<0.001). Other demographic variables and risk factors did not significant difference between the two groups (P>0.05).Conclusion: The results demonstrated that identifying the risk factors could aid in managing aggravating pelvic pain factors during pregnancy and preventing movement restrictions in postpartum women.
Obstetrics and Gynecology
Mohammed Ubaid Hamza; Noora M. Hameed; Sura Hasan Al-Zubaidi; Roua Abulkassim; Zahraa Basim Mohamed; Safaa Saad Mahmood; Dhuha Mohsin Al-Dhalemi; Heba Takleef al Salami; Nathera Hussin Alwan; Doaa A. Hamad
Volume 7, Issue 6 , September and October 2022, , Pages 563-568
Abstract
Background & Objective: Toxoplasmosis is a zoonotic infection caused by Toxoplasma gondii, a parasite that causes a variety of clinical symptoms in humans. It is a facultatively heteroxenous, polyxenous protozoon that has evolved several potential transmission routes within and between the host species. ...
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Background & Objective: Toxoplasmosis is a zoonotic infection caused by Toxoplasma gondii, a parasite that causes a variety of clinical symptoms in humans. It is a facultatively heteroxenous, polyxenous protozoon that has evolved several potential transmission routes within and between the host species. Infections caused by Toxoplasma gondii are more frequently seen in immunocompetent patients. The infection acquired by the mother during pregnancy puts the fetus at risk of congenital infection due to the parasite transmission across the placenta. The severity and frequency of infection are determined by the gestational age of the mother at the time of infection. The objective of this research was to study the toxoplasmosis infection in women, and to estimate the relationship between T. gondii infection and parameters including abortion time, chronic diseases, and age.Materials & Methods: The case-control study was conducted on 50 healthy women (pregnant and non-pregnant) as control group and 135 women with abortion experience as case group at the Women's and Children's Hospital in Baghdad, Iraq from December 2021 until March 2022. The questionnaire was used to gather information from the women. The participant's name, age, gestational age, address, medications taken, medical history, previous abortions, and the date the sample was taken were all included. Under sterile conditions, five milliliters of the venous blood were drawn from each woman. The ELISA test was used to determine the level of anti-T. gondii IgM and IgG antibodies in serum samples.Results: The anti-Toxoplasma IgM and IgG antibodies were found to be positive in 51% and 8% of the cases, respectively. However, the anti-T. gondii antibodies seroprevalence was 59% in women who had abortion. The healthy women had 0% for all antibodies. Conclusion: Despite reporting the high rates of infection among women who had single abortions, the current study found no significant association between the percentage of infection and the number of abortions. The cause of high incidence among women who had abortion could be due to decrease in the immune system function.
Radiology
Sedigheh Ghasemian Dizaj Mehr; Robabeh Bahadori
Volume 8, Issue 6 , November and December 2023, , Pages 637-640
Abstract
Ovarian mature cystic teratomas (OMCTs) due to their heterogeneous histologic entity, have a wide spectrum of radiologic features. A type of floating spherical globule that has been called “Sack of marble” or "Coins-in-sack,” but without a fat or calcification component that results ...
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Ovarian mature cystic teratomas (OMCTs) due to their heterogeneous histologic entity, have a wide spectrum of radiologic features. A type of floating spherical globule that has been called “Sack of marble” or "Coins-in-sack,” but without a fat or calcification component that results in misdiagnosis on computed tomography (CT), is a rare finding. The patient was a 35-year-old healthy woman with abdominal pain and sonographic findings based on OMCT with the Coins-in-sack sign, whereas the CT manifestation was a unilocular huge cyst suggesting an adnexal cystadenoma. She had a final diagnosis of the Coins-in-sack variant of OMCT but with keratin balls, not common fat balls. Understanding the unconventional radiologic and histologic manifestations of OMCTs, is necessary to make an accurate diagnosis.
Obstetrics and Gynecology
Zainab Muayad Essa; Alia Kareem Mohamad AL-Qarawy; Ashwaq Kadhim Mohammed
Articles in Press, Accepted Manuscript, Available Online from 09 March 2024
Abstract
Background: Endocrine disorders like polycystic ovarian syndrome affect reproductive-age women. It causes infertility and has several clinical symptoms. Clomiphene citrate ovulation induction is a first-line treatment. Serum anti-mullerian hormone can indicate positive pregnancy outcomes in women with ...
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Background: Endocrine disorders like polycystic ovarian syndrome affect reproductive-age women. It causes infertility and has several clinical symptoms. Clomiphene citrate ovulation induction is a first-line treatment. Serum anti-mullerian hormone can indicate positive pregnancy outcomes in women with this disease, however this is controversial. Aim of the study:to assess the value of anti-mullerian hormone (AMH) as an anticipator of ovary response to clomiphene citrate in patients with “polycystic ovary syndrome (PCOS). Patients and methods: A cross-sectional study of 50 women diagnosed with Rotterdam-based polycystic ovarian syndrome by two gynaecologists was conducted. The Maternity and Paediatric Teaching Hospital in Diwaniyah Province, Iraq, conducted the study from August 1, 2022, to May 15, 2023, at the obstetrics and gynaecology department. Women with diabetes or hypertension were excluded from the trial. These women sought medical treatment for infertility and received clomiphene citrate to induce ovulation. The findings of hCG urine and blood testing divided women into positive and negative biochemical pregnancy groups. Results: The mean FSH of all recruited women was 5.19±1.14 IU/L, with no significant difference between pregnant and non-pregnant women (p = 0.849). AMH levels were significantly lower in pregnant women compared to non-pregnant women (p< 0.001). The mean AMH was 6.97±2.88 ng/ml for all enrolled women. ROC curve research determined the optimal AMH cutoff value for predicting positive biochemical pregnancy: ≤6.5 ng/ml with 100% sensitivity, 67.7% specificity, and 80.9 % accuracy. Conclusion: Serum anti-mullerian hormone accurately predicts pregnancy success in PCOS women taking clomiphene citrate to induce ovulation.
Obstetrics and Gynecology
Mohammad Reza Zeraati; Hojjat Torkmandi; Mohammad Abdi; Mohammad Reza Jamshidi; Alireza Safaie
Volume 8, Issue 1 , January and February 2023, , Pages 86-94
Abstract
Pyrexia and shivering are the most popular side effects of postpartum administration of misoprostol, but other side effects of this drug are very rare. A 27-year-old pregnant female patient was admitted to Ayatollah Mousavi hospital (Zanjan, Iran), complaining about severe headache and the primary diagnosis ...
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Pyrexia and shivering are the most popular side effects of postpartum administration of misoprostol, but other side effects of this drug are very rare. A 27-year-old pregnant female patient was admitted to Ayatollah Mousavi hospital (Zanjan, Iran), complaining about severe headache and the primary diagnosis of cerebral venous thrombosis. Treatment was successful after primary investigations and planed therapy for Cerebral Venous Thrombosis (CVT). Following the decision on terminating the pregnancy, five tablets of Sublingual misoprostol (200 mg) was used once evacuation of pregnancy remnants was done. About thirty minutes after the administration of misoprostol, onset of severe shivering and tachycardia (201/min) with high fever (about 41°C) and hypertension (182/123 mmHg) was observed. National Adverse Drug Reaction (ADR) form was completed. All of symptoms were alleviated 30 minutes after administration of Paracetamol 1gram (Intravenous infusion) followed by Metoprolol 50 mg (orally). According to the literature, we listed the various side effects of misoprostol. Even though the side effects of misoprostol are diverse and rare, the simultaneous occurrence of these side effects is not cited till date. These incidents are reported to the authorities as per ADR policy; nonetheless, no preventive measures are implemented. This necessitates medical educational policies to be taken into consideration to educate healthcare providers throughout their professional career as well as research.
General Gynecology and Pelvic Floor
Zahra Yazdi; Hoora Amuzegar; Monireh Mirzaie; Seyed Mohammad Hashem Montazeri
Volume 8, Issue 2 , March and April 2023, , Pages 188-193
Abstract
We present a 26-year-old woman with hypothyroidism that was treated with levothyroxine, and was hospitalized at 25 weeks of gestational age with diagnosis of ovarian torsion and underwent detorsion surgery, but finally, after a few weeks and during cesarean section, no trace and evidence of the ovary ...
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We present a 26-year-old woman with hypothyroidism that was treated with levothyroxine, and was hospitalized at 25 weeks of gestational age with diagnosis of ovarian torsion and underwent detorsion surgery, but finally, after a few weeks and during cesarean section, no trace and evidence of the ovary was observed, which suggests the phenomenon of spontaneous ovarian absorption.
Maternal Fetal Medicine
Leili Rezaie Kahkha; Farzaneh Zamani; Khadije Rezaie Keikhaie; Masoumeh Mirteimouri
Volume 9, Issue 2 , March and April 2024, , Pages 225-230
Abstract
Background & Objective: Determining the clinical manifestations of COVID-19 in pregnant and recently pregnant women is important to identify risk factors in order to evaluate complications and maternal and perinatal outcomes. The aim of the present study was to investigate the symptoms of COVID-19 ...
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Background & Objective: Determining the clinical manifestations of COVID-19 in pregnant and recently pregnant women is important to identify risk factors in order to evaluate complications and maternal and perinatal outcomes. The aim of the present study was to investigate the symptoms of COVID-19 in pregnant women and its effects on the newborn.
Materials & Methods: The Now study was a prospective descriptive study. This research was conducted in 2020 on 101 pregnant women with COVID-19 infection admitted to the intensive care unit in Zabol city, Iran. All studied patients were examined in terms of clinical symptoms, maternal and neonatal complications, and laboratory findings such as WBC and ESR in all patients were checked. Finally, all information was entered into each patient's form and by using SPSS V22 software analyzed.
Results: Number of 101 pregnant women participated in the study, with an average age of 31.09 years. In this study, 93 individuals had PCR positive (92.1%), 84 individuals with COVID+ in CT scan (83.2%), 25 individuals with an underlying disease (24.8%), and 54 individuals with addiction (53.5%). 20 feet (19.8%) were reported. 20 deaths (19.8%) were reported. The average BMI of the participants was 25.46. Among maternal complications, pulmonary involvement (71.28%) the most frequently was reported. Among the hospitalized patients (95 individuals), 25 individuals had underlying diseases. In this population, maternal complications were significantly more reported (P value=0.012). Among neonatal complications, the most common cases of death were IUFD and abortion. 62.1% of the participants had a natural delivery and 63.4% had a term delivery.
Conclusion: Fever, throat redness and swelling, respiratory distress and cough are the most common clinical symptoms and lung involvement is the most common complication of COVID infection in pregnant mothers. In infants, IUFD and abortion were also very common. PCR and CT scan are two high-sensitivity tests for detecting COVID.
Gynecology Oncology
Behnaz Nouri; Sara Sarani; Maliheh Arab; Mina Bakhtiari; Fereshte Sarbazi; Anita Karimi
Volume 7, Issue 3 , January and February 2022, , Pages 230-234
Abstract
Background and Objectives: Adnexal masses are among the most important neoplastic lesions observed in women. Considering different results of laparoscopy versus laparotomy for adnexal masses, this study compared the surgical consequences of laparoscopy and laparotomy of adnexal masses.Methods: This prospective ...
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Background and Objectives: Adnexal masses are among the most important neoplastic lesions observed in women. Considering different results of laparoscopy versus laparotomy for adnexal masses, this study compared the surgical consequences of laparoscopy and laparotomy of adnexal masses.Methods: This prospective observational study was performed on females aged 10 to 75 years with adnexal mass referred to the gynecology clinic of Shohaday-e Tajrish Hospital (2019-2020) by convenience sampling. A total of 34 patients in the laparoscopy group and 29 patients in the laparotomy group were included in the study. SPSS 25 was used for data analysis.Results: The mean duration of surgery and anesthesia in laparoscopic patients was significantly more than in the laparotomy patients (P < /em><0.05). There were no significant differences between patients in the two groups in terms of complications during surgery (P < /em>=0.62). The mean of pre-discharge pain (based on scoring from 1 to 10) in laparoscopic patients was significantly lower than in the laparotomy group (3.5 ± 1.2 and 6.7 ± 1.0, respectively, P < /em><0.001). The mean length of hospital stay after surgery was significantly lower in the laparoscopic group compared with the laparotomy group (29 ± 9 hours and 44 ± 7 hours, respectively, P < /em><0.001).Conclusion: Although the use of laparoscopy in adnexal masses is associated with a longer duration of surgery and anesthesia, due to the shorter hospital stay, it can be concluded that the use of laparoscopy in adnexal masses is better than laparotomy.
Obstetrics and Gynecology
Reda Hemida
Volume 7, Issue 4 , March and April 2022, , Pages 356-357
Abstract
Dear Editor- in –Chief of Journal of Obstetrics, Gynecology and Cancer Research (JOGCR),I write to you regarding the published article in The Journal of Obstetrics, Gynecology, and Oncology research titled “The Association of Gestational Trophoblastic Neoplasia and Misoprostol Administered ...
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Dear Editor- in –Chief of Journal of Obstetrics, Gynecology and Cancer Research (JOGCR),I write to you regarding the published article in The Journal of Obstetrics, Gynecology, and Oncology research titled “The Association of Gestational Trophoblastic Neoplasia and Misoprostol Administered Before Suction Curettage of Molar Pregnancy” by Aminimoghaddam et al that was published on 27th of September, 2019 [1]. The article was revised with interest and raised for me some serious concerns.
Gynecology Oncology
Soheila Aminimoghaddam; Zahra Vahedpoor; Shabnam Bozorgzadeh
Volume 8, Issue 4 , July and August 2023, , Pages 417-421
Abstract
Hereditary non polyposis colorectal cancer (HNPCC) also known as Lynch syndrome (LS), is an autosomal dominant cancer syndrome. Besides colorectal cancers, it predisposes patients to extracolonic cancers. Despite several extracolonic cancers have been reported on LS, we found a new face of it. A 43-year-old ...
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Hereditary non polyposis colorectal cancer (HNPCC) also known as Lynch syndrome (LS), is an autosomal dominant cancer syndrome. Besides colorectal cancers, it predisposes patients to extracolonic cancers. Despite several extracolonic cancers have been reported on LS, we found a new face of it. A 43-year-old G2L2 patient with chief complaint of abnormal uterine bleeding. Her endometrium biopsy showed clear cell carcinoma, and the necessary work-ups have been done. But the patient's family history demonstrated HNPCC based on the Amsterdam 2 criteria. After some years, the patient presented to our hospital for fever, shivering and abdominal LUQ pain. Spiral CT scan showed a solid cyst with heterogeneous enhancement in the spleen, and hepatosplenomegaly. In this paper, another case with endometrial cancer as a sentinel cancer of LS is reported. This fact implicate that physicians should notice the family history of malignancies in patients with gynecologic cancers and consider LS.
Obstetrics and Gynecology
Sedigheh Ghasemian; Somayeh Ghasemzadeh; Ali Soleimany
Volume 7, Issue 5 , July and August 2022, , Pages 466-470
Abstract
Clindamycin, IVIg, and corticosteroids are widely used in medicine. In this study, we represent an unusual case of sinus bradycardia following the administration of these drugs. The patient was a 31-year-old woman who presented a complaint of vaginal bleeding at Shahid Motahhari Hospital, Urmia, Iran. ...
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Clindamycin, IVIg, and corticosteroids are widely used in medicine. In this study, we represent an unusual case of sinus bradycardia following the administration of these drugs. The patient was a 31-year-old woman who presented a complaint of vaginal bleeding at Shahid Motahhari Hospital, Urmia, Iran. Vaginal examination revealed active bleeding. Laboratory tests reported a positive HCG level. Ultrasonography was performed, and the results showed the presence of retained products of conception. The patient became a candidate for curettage. The initial pulse rate was tachycardia. Laboratory data were reported, platelet count of 16000. corticosteroids and IVIgs were started. Due to the possibility of infectious abortion, Clindamycin and Gentamicin was started. About 24 hours after curettage and 4 hours after starting clindamycin, the patient felt dizziness. Vital signs were obtained that PR: 38-40. We concluded that clindamycin and IVIg can result in severe bradycardia, even in patients with no previous cardiac history, especially when combined with corticosteroids. As a result, we recommend physicians be more cautious when administrating these medications.
General Gynecology and Pelvic Floor
Zinat Ghanbari; Maryam Deldar Pesikhani; Parivash Jelodarian; Reihane Sadat Hosseini
Volume 8, Issue 5 , September and October 2023, , Pages 528-532
Abstract
Postoperative abscess after colpocleisis is rare. We reported a 67-year-old woman with an abscess after a month of Le Fort colpocleisis. Two abscesses of approximately 5 cm in size were drained. The injection of antibiotics continued up to 7 days after the surgery, and the drain was taken on the 4th ...
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Postoperative abscess after colpocleisis is rare. We reported a 67-year-old woman with an abscess after a month of Le Fort colpocleisis. Two abscesses of approximately 5 cm in size were drained. The injection of antibiotics continued up to 7 days after the surgery, and the drain was taken on the 4th day after the operation due to the improvement of the patient's general conditions and no discharge. It is recommended to consider pelvic abscess in patients suffering from fever, pain, pelvic pressure, and diarrhea after pelvic surgeries. Early diagnosis and treatment will reduce mortality and disability in patients.
Gynecology Oncology
Maryam Talayeh; Maliheh Arab; Somayyeh Noei Teymoordash; Noushin Afsharmoghadam; Masoomeh Raoufi; Behnaz Ghavami; Mahsa Asghari
Volume 7, Issue 6 , September and October 2022, , Pages 569-573
Abstract
Endometrial stromal sarcoma is a rare condition, constituting nearly 0.2% of all reproductive tract malignancies. The condition mainly affects the peri-menopausal population; however, it can occasionally be found in younger women and adolescents. Here, this is a case of a 20-year-old primiparous ...
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Endometrial stromal sarcoma is a rare condition, constituting nearly 0.2% of all reproductive tract malignancies. The condition mainly affects the peri-menopausal population; however, it can occasionally be found in younger women and adolescents. Here, this is a case of a 20-year-old primiparous female who was referred to us with the main complaint of vaginal bleeding (menometrorrhagia), ongoing for 6 months after delivery. Her sonography report indicated a 5 cm intra-cavitary mass suspicious for myoma or placental polyp. Given the pathology report of low-grade endometrial stromal sarcoma (LGESS) on samples obtained through hysteroscopy and D&C, she underwent total abdominal hysterectomy and bilateral salpingo-oophorectomy (TAH+BSO). Endometrial stromal sarcoma is a rare uterine malignancy of mesenchymal origin that should be considered, even in very young patients.
Obstetrics and Gynecology
Sowmya Shree Thimmappa; KB Suma
Volume 8, Issue 6 , November and December 2023, , Pages 641-644
Abstract
Guillain-Barré syndrome is a rare neurological complication that presents in pregnancy and postpartum. We present a case of a 23-year-old Gravida 2 Para 1 Living 1 with 39 weeks of gestation and previous lower (uterine) segment cesarean section (LSCS) who presented with nonspecific symptoms ...
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Guillain-Barré syndrome is a rare neurological complication that presents in pregnancy and postpartum. We present a case of a 23-year-old Gravida 2 Para 1 Living 1 with 39 weeks of gestation and previous lower (uterine) segment cesarean section (LSCS) who presented with nonspecific symptoms in the antenatal period and progressed to develop symmetrical progressive ascending paralysis in the postpartum period with no antecedent history of infection. The patient was managed by a multidisciplinary team and treated with plasma exchange, with complete recovery at follow-up. We are reporting this case because of the rarity of Guillain-Barre syndrome in pregnancy and postpartum and the nonspecific initial presentation with an unexpected diagnosis in the immediate postpartum.
