Iranian Society of Gynecology Oncology
Gynecology Oncology
Evaluation of tumor markers (CEA, CA 15-3, CA 125) in endometrial cancer differentiation and abnormal uterine bleeding

Pegah Sasanpour; Narjes Noori; Maryam Nazemian; Narjes Noori; Hossein Ansari

Articles in Press, Accepted Manuscript, Available Online from 03 March 2024

Abstract
  Background: Endometrial cancer is the most common malignancy of the genital system. it is needed to assess discrimination power of tumor markers (CEA, CA 15-3, CA 125) in patients with endometrial cancer and patients with abnormal uterine bleeding. we examined tumor markers (CA 15-3, CA 125, CEA) in ...  Read More

Gynecology Oncology
The role of the meaning of life in death anxiety and suicidal thoughts of women with cancer

Hedyeh Mansoori; Mahmoud Shirazi

Articles in Press, Accepted Manuscript, Available Online from 01 January 2024

Abstract
  Background & Objective: This research was with the aim of checking the role of the meaning of life in death anxiety and suicidal thoughts of women with cancer.Materials & Methods: The method of this research is a correlation. The statistical crowd of the perusal included all women with cancer ...  Read More

Gynecology Oncology
A Prospective Study Assessing Sexual Function and Body Image Among Cervical Cancer Survivors: Exploring Treatment Modality Differences

JORGE CEA GARCÍA; FRANCISCO MÁRQUEZ MARAVER; INMACULADA RODRÍGUEZ JIMÉNEZ; LAURA RÍOS-PENA; M. CARMEN RUBIO RODRÍGUEZ

Articles in Press, Accepted Manuscript, Available Online from 03 March 2024

Abstract
  Background & objectivesWe aimed to compare sexual function and body image among cervical cancer survivors.Materials & MethodsBetween August 1, 2016, and January 31, 2019, we conducted a prospective study with 104 participants. The FSFI and the FACT-Cx v.4.0 (B4-C7) were the measurements.ResultsSome ...  Read More

Gynecology Oncology
DEVELOPMENT AND INTERNAL VALIDATION OF A MULTIVARIABLE PREDICTION MODEL FOR THE SEXUAL FUNCTION OF CERVICAL CANCER SURVIVORS

JORGE CEA GARCÍA; M. CARMEN RUBIO RODRÍGUEZ; FRANCISCO MÁRQUEZ MARAVER; LAURA RÍOS-PENA; INMACULADA RODRÍGUEZ JIMÉNEZ

Articles in Press, Accepted Manuscript, Available Online from 03 March 2024

Abstract
  Background & objectives: Sexual dysfunction is the symptom with the greatest negative impact on the quality of life of cervical cancer survivors. However, the assessment of sexual function is difficult and its predictors remain controversial. We aimed to identify predictive variables for sexual function ...  Read More

Gynecology Oncology
The supplemental effect of Vitamin-D3 and Omega-3 on induced endometriosis rat model to investigate the inflammatory response

Zahra Shiravani; Fatemehsadat Najib; Mahvash Alirahimi; Elham Askary; Tahereh Poordast; Nader Tanideh; Shohreh Roozmeh; Golsa Shekarkhar; Sana Atbaei; danilo porro; Soudabeh Sabetian; Claudia Cava

Articles in Press, Accepted Manuscript, Available Online from 03 September 2023

Abstract
  The endometriosis treatment was critical issue due to complications associated with current drug delivery system. Present investigation compared the curative effect of Vitamin D3 (VTD3) and Omega–3 (OG3) with Diphereline during the treatment of endometriosis. Endometriosis was induced in different ...  Read More

Gynecology Oncology
Retrospective Analysis of Uterine Sarcoma Cases Managed by a Single Institute

Ahmad Shuib Yahaya; Mohd Norazam Mohd Abas; Jamil Omar

Articles in Press, Accepted Manuscript, Available Online from 18 November 2023

Abstract
  Objective: This study aims to analyze the survival outcomes and prognostic factors of patients with uterine sarcoma in the Department of Gynae-Oncology, between June 2015 and December 2022. Methods: The study population consists of patients with histopathologically confirmed uterine sarcoma. Oncological ...  Read More

Gynecology Oncology
Prevalence of endometrial hyperplasia and its related factors in patients with AUB

farahnaz farzaneh; Shahla Mirgaloybayat; Abbas Ali Niazi; Marziyeh Ajdary; Javid Dehghan Haghighi; Neda Eslahi; Mohammad Raisi

Articles in Press, Accepted Manuscript, Available Online from 20 November 2023

Abstract
  Background & Objective: Endometrial hyperplasia is the primary precursor of endometrial cancer in the female reproductive system, with abnormal uterine bleeding (AUB) being the predominant manifestation of this condition. The purpose of this study was to determine the prevalence of endometrial hyperplasia ...  Read More

Gynecology Oncology
Epidemiological study of the role of cranberry in the prevention and in the treatment of UTIs when combined with antibiotic therapy

Zahraa Al-Tamimi; Mahmood A. Al Ani

Articles in Press, Accepted Manuscript, Available Online from 11 January 2024

Abstract
  Background: Asymptomatic bacteruria is a form of lower urinary tract infections (UTIs) that is significant during pregnancy for its high prevalence, high tendendency for persistence and progression to the other symptomatic forms, besides posing adverse effects on pregnancy through effects on both maternal ...  Read More

Gynecology Oncology
INTERLEUKIN 6 EXAMINATION AS A MARKER OF PRE-SURGICAL EPITHELIAL TYPE OF OVARIAN MALIGNANCY: A CROSS-SECTIONAL STUDY

Aida Uzaya; Syahrul Rauf; Trika Irianta; Firdaus Hamid; John Rambulangi; Abdul Rahman

Articles in Press, Accepted Manuscript, Available Online from 12 February 2024

Abstract
  Background and Aim: Ovarian cancer affects women worldwide. Immunoregulatory cytokines, particularly interleukin (IL)-6, can enhance tumorigenicity and are persistently secreted by ovarian cancer cells. This study aims to examine IL-6 as a marker of preoperative epithelial ovarian malignancy. Methods: ...  Read More

Gynecology Oncology
Clinicopathological Implications of serum level of IL-27 in endometrial cancer Patients

Fatemeh Sedaghat; zahra Shiravani; Ali Mohammad Karimi; Mohammad Reza Haghshenas; Abbas Ghaderi; Mohammad Javad Fattahi

Articles in Press, Accepted Manuscript, Available Online from 02 March 2024

Abstract
  Objective: Endometrial cancer (EC) is the most prevalent gynecological malignancy in more developed countries. Multiple researches have been done about the role of IL-27 in different cancers that suggest a dual role for this cytokine. In the present study, we evaluated the serum level of IL-27 in endometrial ...  Read More

Gynecology Oncology
Clinical, Laboratory and Imaging Characteristics of Women with Uterine Fibroid: A Cross-Sectional Study from Iran

Farah Farzaneh; Shaghayegh Hooshmand Chayijan; Hanieh Najafi Arab; Farima Rahimi Mansour; Amirreza Keyvanfar; Zahra Bakhtiyari

Volume 9, Issue 1 , January and February 2024, , Pages 45-52

Abstract
  Background and Objective: Uterine fibroids (UFs) the most common pelvic tumors among women at reproductive age affecting women’s quality of life even their confidence with its symptoms. We designed a study to investigate the clinical, laboratory, and imaging characteristics of Iranian women with ...  Read More

Gynecology Oncology
Correlation Between Amniotic Fluid Alpha-Fetoprotein and Adverse Pregnancy Outcomes

Forozan Milani; Seyedeh Hajar Sharami; Negar Gholamalipour; Ehsan Kazemnezhad Leyli; Seyedeh Fatemeh Dalil Heirati; Yalda Donyaei-Mobarrez

Volume 9, Issue 1 , January and February 2024, , Pages 53-62

Abstract
  Background: Evaluation of the alpha-fetoprotein is one of the screening tests during pregnancy. The purpose of this study was to determine the relationship between the level of alpha-fetoprotein in amniotic fluid (AF-AFP) and adverse pregnancy outcomes.Materials and methods: This comparative analytical ...  Read More

Gynecology Oncology
The Importance of Other HPV in High-Grade CIN

Farah Farzaneh; Elnaz Ghaffari; Maryam Sadat Hosseini; Tahereh Ashraf Ghanjouee; Afsaneh Hosseini

Volume 8, Issue 6 , November and December 2023, , Pages 571-578

Abstract
  Background & Objective: High-risk (HR) HPV infection is the major cause of cervical cancer, which is still one of the most common cancers among women. Based on some not-published results, it seems that some of the other HR HPVs might be as important as HPV 16, and 18 in developing high-grade ...  Read More

Gynecology Oncology
Luteinizing Hormone Levels as an Indicator of the Timing of Antagonist Administration in a Gonadotropin-Releasing Hormone Antagonist Protocol

May Kassim Khalaf; Fadia J Alizzi; Ammar Mohammed Qassim

Volume 8, Issue 6 , November and December 2023, , Pages 599-606

Abstract
  Background & Objective: Gonadotropin-releasing hormone acts on the anterior pituitary and promotes the release of both follicle-stimulating hormone (FSH) and luteinizing hormone (LH), both of great importance in the ovarian cycle.Materials & Methods: In a prospective cross-sectional ...  Read More

Gynecology Oncology
Primary Bilateral Fallopian Tube Carcinoma: A Rarity

Isha Nandal; Roopa Malik; Krishna Dahiya

Volume 8, Issue 6 , November and December 2023, , Pages 633-636

Abstract
  Primary fallopian tube carcinoma is a very rare gynecological malignancy and poses a challenge in diagnosis preoperatively. We are reporting a rare case of bilateral primary fallopian tube carcinoma in a 48-year-old lady with classical symptoms. These symptoms are seen in less than 15% of cases. The ...  Read More

Gynecology Oncology
Primary Uterine Cervix B-Cell Lymphoma: A Case Report and Treatment Debates

Mastaneh Sanei; Hamidreza Dehghan; Nadereh Behtash

Volume 8, Issue 6 , November and December 2023, , Pages 645-649

Abstract
  Non-Hodgkin lymphomas are a heterogeneous group of lymphoproliferative disorders with various behaviors and responses to treatment. As a primary extranodal NHL, the disease must be confined to one location, and bone marrow should not be involved. Primary uterine cervix lymphoma is a rare malignancy as ...  Read More

Gynecology Oncology
Molecular Epidemiology of Breast Cancer in Iran: A Review Article

Roya Dolatkhah; Mehrnaz Hosseinalifam; Zohreh Sanaat; Neda Dolatkhah; Saeed Dastgiri

Volume 8, Issue 5 , September and October 2023, , Pages 422-430

Abstract
  Breast cancer (BC) was the most common cancer in Iran, accounting for 12.9% of all incident cancer, and was the 5th leading cause of cancer death in 2020. The latest age standardized incidence rate (ASIR) of breast cancer was 35.8 in Iran and is expected to increase to more than 70 per 100,000 by the ...  Read More

Gynecology Oncology
Preserving Fertility and Its Outcomes in Iranian Women with Cancer: A Longitudinal Cohort Study

Batool Hossein Rashidi; Marjan Ghaemi; Ensieh Shahrokh Tehrani; Marzieh Mohebbi; Marzieh Savari

Volume 8, Issue 5 , September and October 2023, , Pages 446-456

Abstract
  Background & Objective: Preserving fertility in women with cancer before therapeutic interventions is very important. This study was evaluating the 8 years’ experience of an onco-fertility center from 2013 to 2020 on fertility preservation and its outcomes in female cancer survivors.Materials ...  Read More

Gynecology Oncology
Anatomical Sites and Characteristics of EndometriosisLesions: Laparoscopic Investigation

Behnaz Nouri; Malihe Arab; Nazli Najeddin Choukan

Volume 8, Issue 5 , September and October 2023, , Pages 494-500

Abstract
  Background & Objective: Endometriosis is a common and benign disease of the female genital system, which is often seen in reproductive age and leads to infertility, dysmenorrhea, and dyspareunia. The aim of this study is to investigate the anatomical location and characteristics of endometriosis ...  Read More

Gynecology Oncology
The Role of Thrombophilia Factors Polymorphism and Cytogenetic Analysis in Recurrent Pregnancy Loss (RPL) in Northeastern Iran

Mohammad Reza Javan; Bahareh Moghimian-Boroujeni; Hossein Ayatollahi; Amirali Ayatollahi; Nafise Amini; Elham Jafaei; Maryam Sheikhi; Narjes Soltani

Volume 8, Issue 4 , July and August 2023, , Pages 342-349

Abstract
  Background & Objective: Recurrent pregnancy loss (RPL) is the occurrence of three or more miscarriages before the 20th week of pregnancy. Thrombophilia factors are one of the common causes of RPL.Materials & Methods: This retrospective study was performed on women with miscarriages. ...  Read More

Gynecology Oncology
Comparative Study Between Superficial and Deep Myometrial Invasion in Endometrial Cancer Type 1 in Relation to Regional Lymph Nodes Metastasis

Hossam Hassan Aly Hassan El Sokkary

Volume 8, Issue 4 , July and August 2023, , Pages 357-365

Abstract
  Background & Objective: The present study compares between superficial and deep myometrial invasion in type 1 endometrial cancer in relation to regional lymph nodes metastasis, so we can answer the question to do or not do lymphadenectomy, this life-threatening procedure in both superficial ...  Read More

Gynecology Oncology
Patients with Trachelectomy Surgery Sexual Performance Domains in Cervical Cancer Patients

Alsmadi Yaseen Mohammad Ibrahim; Saad Altimimi; Aisha Kamal Mahmoud; Muqdad Hussein Ali; Naseer Mehdi Mohammed; Ruqayah Taher Habash; Ahmed S Abed; Entsar Hachim Muhammad

Volume 8, Issue 4 , July and August 2023, , Pages 396-403

Abstract
  Background & Objective: Today, the prevalence of cervical cancer in developing societies and its impacts on various body functions, mainly sexual performance, is of particular significance. In order to examine the relationship between sexual function and its domains with different stages of ...  Read More

Gynecology Oncology
Radical Surgery in Cervical Cancer Survivors: Shat is the Matter of Concern in Low-Resources Societies?

Ghodratolah Maddah; Mohammad Ali Mohammadzadeh Rezae; Zohreh Yousefi; Helena Azimi; Leila Mousavi Seresht

Volume 8, Issue 4 , July and August 2023, , Pages 411-416

Abstract
  Background & Objective: Pelvic exenteration and other types of super-radical procedures are the standard of care in the management of patients with recurrent or persistent cervical cancer. But, since the extent of surgery and possible morbidities are considered as an important challenge in low-resource ...  Read More

Gynecology Oncology
Metastasis to Spleen in a Lynch Syndrome Patient: A Case Report

Soheila Aminimoghaddam; Zahra Vahedpoor; Shabnam Bozorgzadeh

Volume 8, Issue 4 , July and August 2023, , Pages 417-421

Abstract
  Hereditary non polyposis colorectal cancer (HNPCC) also known as Lynch syndrome (LS), is an autosomal dominant cancer syndrome. Besides colorectal cancers, it predisposes patients to extracolonic cancers. Despite several extracolonic cancers have been reported on LS, we found a new face of it. A 43-year-old ...  Read More

Gynecology Oncology
Impact of Serum CA19-9 Level in Clinico- Pathological and Radiologic Feature of Mature Cystic Teratoma: A Case Series

Sedigheh Ghasemian Dizajmehr; Mahsa Mohammadi Irvanlou; Afshin Mohammadi; Farzaneh Rashidi Fakari

Volume 8, Issue 3 , May and June 2023, , Pages 295-300

Abstract
  Background & Objective: Ovarian mature cystic teratomas (OMCTS) are one of the most common benign ovarian tumors. Most MCTs can be diagnosed by ultrasonography (us). Due to heterogeneous composition and a variety of appearance, in some non-diagnostic imaging reports it is suggested that we evaluate ...  Read More