General Gynecology and Pelvic Floor
Elham Akbari; Fereshteh Sarbazi; Behnaz Nouri; Anita Karimi; Sahar Khoshravesh
Articles in Press, Accepted Manuscript, Available Online from 26 April 2024
Abstract
Background: Nowadays, the prevalence of uterine myoma in pregnant women has increased due to the increasing age of pregnancy in women. Due to the possibility of bleeding andmiscarriage, the surgical management of uterine myoma with myomectomy is limited, andmany obstetricians and gynaecologists recommend ...
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Background: Nowadays, the prevalence of uterine myoma in pregnant women has increased due to the increasing age of pregnancy in women. Due to the possibility of bleeding andmiscarriage, the surgical management of uterine myoma with myomectomy is limited, andmany obstetricians and gynaecologists recommend that myomectomy be performed afterdelivery. In this case report, a pregnant woman (window period) with a negative result of ßhCG test and ultrasound in terms of pregnancy undergoes myomectomy surgery to remove a large uterine myoma.Case presentation: A 40-year-old patient referred to the physician because of vaginalbleeding caused by a large uterine myoma and primary infertility for 10 years. ßhCG test andultrasound of the patient was negative in terms of pregnancy and she underwentmyomectomy surgery while the patient is in the early stages of pregnancy (window period).Therefore, the patient was under the supervision of a gynecologist and was visited everyweek. With continuous follow-up, the newborn was born without any problems at 37 weeks. Conclusion: Although in this study with proper management during surgery, progesteronetherapy and continuous and regular follow-ups, the newborn was born healthy, butconfirmation of myomectomy during pregnancy requires the implementation of more studies.
Obstetrics and Gynecology
Leila Mousavi Seresht; Amir Reza Farhadi Dehkordi; Azar Danesh Shahraki; Pegah Hedaiat; Fedyeh Haghollahi
Volume 9, Issue 1 , January and February 2024, , Pages 102-105
Abstract
Invasive angiomyxoma as a mesenchymal tumor with a high recurrence rate has been reported mainly in reproductive age according to its association with the estrogenic level of plasma. Above that, it seems there is a need for further treatment despite complete resection of the tumor, to eliminate the hormonal ...
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Invasive angiomyxoma as a mesenchymal tumor with a high recurrence rate has been reported mainly in reproductive age according to its association with the estrogenic level of plasma. Above that, it seems there is a need for further treatment despite complete resection of the tumor, to eliminate the hormonal state. In the present study, we sought to introduce a rare case of invasive angiomyxoma in a post-menopausal but high-risk woman, discuss the relativity of risk factors in all hormonal-dependent gynecological malignancy, and intend to seek help from colleagues' opinions and experiences about treatment. It is clearly of great importance to emphasize the role of individualized medicine in such a rare case, in conclusion, there is not any debate on the role of surgical resection but the necessity of changing in lifestyle or adjuvant systemic or local therapy, and the needed duration is doubtful.
Obstetrics and Gynecology
Soudabeh Kazemi Aski; Shiva Alizadeh; Saghi Ghafourian Abadi; Fereshteh Yaseri Gilvaei; Seyedeh Marzieh Kiai
Volume 7, Issue 3 , January and February 2022, , Pages 235-242
Abstract
Background and Objective: With the outbreak of the new coronavirus, some sections of society are more vulnerable, including pregnant women. Today, with the pandemic of COVID-19, anxiety, and worries about pregnancy and fetal health have increased and will be associated with adverse consequences ...
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Background and Objective: With the outbreak of the new coronavirus, some sections of society are more vulnerable, including pregnant women. Today, with the pandemic of COVID-19, anxiety, and worries about pregnancy and fetal health have increased and will be associated with adverse consequences for the health of mothers and infants. There is also insufficient information on the effects of coronary heart disease and COVID-19 on the fetus and pregnancy. Therefore, this study aimed to examine the level of awareness of pregnant women about coronavirus disease (COVID-19) and its correlation with observed stress in pregnant women.Methods: This cross-sectional analytical research was conducted on 384 pregnant women who were referred To Al-Zahra Medical Center at Rasht, Iran in 2020 and were selected through simple random sampling. Data collection tools were a demographic questionnaire, standard perceived stress questionnaire, and a researcher-made questionnaire on COVID-19 disease. Using statistical tests, the collected information was analyzed using SPSS 23 at an importance level of less than 0.05.Results: The average scores of pregnant women's knowledge about the signs, symptoms, and ways of transmitting coronavirus are lower than the scores of mothers' awareness about the cause of the disease and how to prevent it. However, in general, the average score of pregnant women' knowledge about COVID-19 is high. Also, the mean scores of concern about COVID-19 and perceived stress of pregnant women about this disease in this reading are high. The present study's findings showed that the amount of knowledge of pregnant women about COVID-19 has a statistically significant relationship with anxiety and perceived stress about this disease and has a positive correlation.Conclusion: This study's results showed that the more pregnant women are aware of COVID-19, the more anxious and stressed they are. As a result, to provide psychological support to pregnant women during pregnancy, medical staff training, the help of social media, and psychiatric experts can minimize harm to them and their fetuses.
Obstetrics and Gynecology
Soheila Aminimoghaddam
Volume 7, Issue 4 , March and April 2022, , Pages 358-360
Abstract
Response to the editor letter Dear Professor Behtash,I am writing this letter to respond to the letter written by Professor Reda Hemida from Mansoura University, Egypt, regarding a publication of mine titled “The Association of Gestational Trophoblastic Neoplasia and Misoprostol Administered ...
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Response to the editor letter Dear Professor Behtash,I am writing this letter to respond to the letter written by Professor Reda Hemida from Mansoura University, Egypt, regarding a publication of mine titled “The Association of Gestational Trophoblastic Neoplasia and Misoprostol Administered Before Suction Curettage of Molar Pregnancy,” published in 2019 in your journal.I want to first thank Professor Hemida for reading my paper carefully and sharing his comments. I highly believe that sharing comments and raising scientific questions could benefit our society. I hope that the responses that the co-authors have provided be helpful and to the point. As he suggested, I am willing to let the journal publish the responses in the next issue.
Maternal Fetal Medicine
Seyedeh Noushin Ghalandarpoor-Attar; Fatemeh Rahimi-Sharbaf; Seyedeh Mojgan Ghalandarpoor-Attar
Volume 8, Issue 5 , September and October 2023, , Pages 533-537
Abstract
As widespread prophylaxis with anti-D Antibodies has dramatically diminished anti-D-associated hemolytic disease of the newborn (HDN), other antibodies-associated HDN has become relatively more significant. Two genes encode Rh proteins: the RhD gene coding for the D and the Rh CcEe gene coding for Cc ...
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As widespread prophylaxis with anti-D Antibodies has dramatically diminished anti-D-associated hemolytic disease of the newborn (HDN), other antibodies-associated HDN has become relatively more significant. Two genes encode Rh proteins: the RhD gene coding for the D and the Rh CcEe gene coding for Cc Ee Antigens. D is a rare Rh phenotype in which RBCs lack Cc/Ee antigens while D antigen is strongly expressed. Anti R17 antibodies are important monomorphic antibodies acting against all previously mentioned antigens. It can pass through the placenta as a G immunoglobulin, leading to fetal or neonatal hemolysis. Here, we reported an immunized pregnant female with D- - phenotype and a history of intrauterine fetal death who had high titer of anti-Rh17 antibodies in her subsequent pregnancy. We would discuss our management strategy which led to good perinatal outcomes. To the best of our knowledge, this is the second case of HDN reported in English written literature in Iran.
Obstetrics and Gynecology
Fatemeh Golshahi; Behnaz Moradi; Forough Jabbari; Marjan Ahmadi
Volume 7, Issue 6 , September and October 2022, , Pages 574-577
Abstract
Fraser syndrome is a rare genetic disorder characterized by multiple structural abnormalities, above all of which are cryptophthalmos and syndactyly. According to reviews of reported cases, diagnostic criteria have been established. Here, we report a case of 18 weeks pregnancy diagnosed with Fraser syndrome ...
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Fraser syndrome is a rare genetic disorder characterized by multiple structural abnormalities, above all of which are cryptophthalmos and syndactyly. According to reviews of reported cases, diagnostic criteria have been established. Here, we report a case of 18 weeks pregnancy diagnosed with Fraser syndrome presenting with cryptophthalmos, syndactyly, kidney agenesis, and hyper-echogenic lungs during an ultrasound examination. The pregnancy was terminated, and diagnostic features of the syndrome were confirmed afterward. Since the imaging characteristics are unique, it is of value that clinicians become familiar with the appearance of the syndrome to provide families with the opportunity to make timely decisions regarding pregnancy termination and use the prenatal diagnostic tools to have healthy children in subsequent pregnancies.
Gynecology Oncology
Mastaneh Sanei; Hamidreza Dehghan; Nadereh Behtash
Volume 8, Issue 6 , November and December 2023, , Pages 645-649
Abstract
Non-Hodgkin lymphomas are a heterogeneous group of lymphoproliferative disorders with various behaviors and responses to treatment. As a primary extranodal NHL, the disease must be confined to one location, and bone marrow should not be involved. Primary uterine cervix lymphoma is a rare malignancy as ...
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Non-Hodgkin lymphomas are a heterogeneous group of lymphoproliferative disorders with various behaviors and responses to treatment. As a primary extranodal NHL, the disease must be confined to one location, and bone marrow should not be involved. Primary uterine cervix lymphoma is a rare malignancy as well as a rare site of extranodal lymphoma. Because of the rarity of the disease, there is no standard treatment guideline for women with primary uterine cervix lymphoma. Patients mostly present with abnormal uterine bleeding, vaginal discharge or pelvic pain. Typically, a pap smear may not show the malignant cells in the specimen. When the diagnosis is made, management may be debated due to its rarity and lack of standard treatment. Surgery, chemotherapy, chemo-immunotherapy and radiotherapy, either alone or in combination, are the treatment options. Most patients respond well to chemotherapy and radiation therapy. The prognosis is usually favorable. Here, we report a case of primary cervical lymphoma in a 50-year-old woman who presented with abnormal vaginal bleeding. She was treated with radiotherapy and chemo-immunotherapy and remained disease-free after nine months of treatment.
Farnoush Farzi; Sodabeh Kazemi; Ziba Zahiri Sorouri; Samaneh Ghazanfar; Mahin Tayefeh Ashrafiyeh; Mandana Javanak; Mohammad Shahbazi
Articles in Press, Accepted Manuscript, Available Online from 14 November 2022
Abstract
Having body mass index more than 29 is described as obesity in pregnancy. Anesthesia management in these patients has always been challenging. A 41-year-old woman, at 37weeks’ gestation with the weight of 200kg and body mass index of 66/05 was admitted with complaint of pain to Al-Zahra Hospital ...
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Having body mass index more than 29 is described as obesity in pregnancy. Anesthesia management in these patients has always been challenging. A 41-year-old woman, at 37weeks’ gestation with the weight of 200kg and body mass index of 66/05 was admitted with complaint of pain to Al-Zahra Hospital in Rasht. She reported a history of two previous caesarean sections and high blood sugar and hypothyroidism which were under control by drugs. The Anesthesiology team decided to choose Continuous Spinal Anesthesia method for her. After performing anesthesia, cesarean delivery was done and a female neonate was born with Apgar score of 5-9. They were discharged from the hospital in good condition after two days. Based on the results of this study, CSA approach is a suitable method for anesthesia management in cesarean section of obese patients. Also it is necessary to recommend these patients to refer to anesthesia counseling clinics before giving birth.
Obstetrics and Gynecology
Zahra Rafiei-Sorouri; Zahra Haghparast Ghadim-limudahi; Azade Mahmoodi Isaabadi
Volume 9, Issue 1 , January and February 2024, , Pages 106-109
Abstract
Mucinous carcinoma is a tumor composed of gastrointestinal-type cells with intracytoplasmic mucin. They are unilateral solid-cystic masses. A 38-year-old G2 L2 woman with a complaint of rapidly increasing severe abdominal distension was referred. Surgery was performed and a huge complicated mass showed ...
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Mucinous carcinoma is a tumor composed of gastrointestinal-type cells with intracytoplasmic mucin. They are unilateral solid-cystic masses. A 38-year-old G2 L2 woman with a complaint of rapidly increasing severe abdominal distension was referred. Surgery was performed and a huge complicated mass showed up. We sucked about 42 liters of brown color fluid out of the cyst and then we could extract the residual mass. Chemotherapy protocol began under the supervision of oncologic service. Despite diagnostic delay, before any dissemination the cystadenocarcinoma was removed. To our best knowledge, our patient had the biggest tumor among other previous case presentations.
Obstetrics and Gynecology
Sedigheh Ghasemian Dizaj Mehr; Robabeh Bahadori
Volume 9, Issue 2 , March and April 2024, , Pages 231-234
Abstract
Management of hemoperitoneum due to ruptured ovarian cyst in patients on anticoagulation is a dilemma. Low threshold of surgery intervention may increase the risk of some events operatively. There is a trend for less invasive treatment in highly selected patients. We present two cases of ...
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Management of hemoperitoneum due to ruptured ovarian cyst in patients on anticoagulation is a dilemma. Low threshold of surgery intervention may increase the risk of some events operatively. There is a trend for less invasive treatment in highly selected patients. We present two cases of massive hemoperitoneum due to ruptured ovarian cyst that were on anticoagulation. Successful conservative management was done in both of them and one patient, due to refractory abdominal pain, required interventional radiologic drainage, instead of surgery approach with good outcome. Ovulation suppression was started in both of them with regular uneventful follow up heretofore. Less invasive management is preferred in carefully selected patients of hemoperitoneum in women on anticoagulation. Ovulation suppression to avoid recurrence must be emphasized.
Obstetrics and Gynecology
Fatemeh Keikha; Mahshid Shooshtari; Narges Zamani
Volume 7, Issue 3 , January and February 2022, , Pages 243-246
Abstract
Intravaginal misoprostol is used worldwide with excellent results for second-trimester pregnancy termination. However, it has a rare but serious complication of uterine rupture, both in previously scarred and unscarred uteri. In this report, we present a case of this rare complication in an unscarred ...
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Intravaginal misoprostol is used worldwide with excellent results for second-trimester pregnancy termination. However, it has a rare but serious complication of uterine rupture, both in previously scarred and unscarred uteri. In this report, we present a case of this rare complication in an unscarred uterus during termination with misoprostol. Uterine rupture was found on laparotomy after the patient showed signs of shock during termination. A 2- to 3-cm laceration was detected in the uterine wall along with the left cornea. The placenta was attached to the uterus on the other side. We found an unusual pregnancy in the cornea and successfully repaired it. Although using misoprostol for termination is safe, a regimen protocol should be established. However, uterine structure and implantation safety should be confirmed before administrating misoprostol. This case highlights a difficult diagnosis of abnormal placentation, especially cornual ectopic pregnancy.
Gynecology Oncology
Behnaz Nouri; Sara Sarani; Maliheh Arab; Mina Bakhshali-Bakhtiari; Fereshte Sarbazi; Anita Karimi
Volume 7, Issue 4 , March and April 2022, , Pages 361-361
Abstract
CORRIGENDUM : In the version of this article initially published, the name of author Mina Bakhshali-Bakhtiari was incorrectly written as Mina Bakhtiari.[J. Obstet. Gynecol. Cancer Res. 2022;7(3):230-234] published article with the doi of http://dx.doi.org/10.30699/jogcr.7.3.230
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CORRIGENDUM : In the version of this article initially published, the name of author Mina Bakhshali-Bakhtiari was incorrectly written as Mina Bakhtiari.[J. Obstet. Gynecol. Cancer Res. 2022;7(3):230-234] published article with the doi of http://dx.doi.org/10.30699/jogcr.7.3.230
Obstetrics and Gynecology
Eighty Mardiyan Kurniawati; Gatut Hardianto; Hari Paraton; Tri Hastono Setyo Hadi; Anis Widyasari; Anisah Nur Rahmawati
Volume 8, Issue 5 , September and October 2023, , Pages 538-541
Abstract
Vaginismus is a medical condition characterized by involuntary tightening of the muscles around the vagina. This situation disrupts sexual relations and impacts the chances of pregnancy. This study explores the occurrence of pregnancy in women with vaginismus after treatment in 2022 in East Java Indonesia. ...
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Vaginismus is a medical condition characterized by involuntary tightening of the muscles around the vagina. This situation disrupts sexual relations and impacts the chances of pregnancy. This study explores the occurrence of pregnancy in women with vaginismus after treatment in 2022 in East Java Indonesia. There were 60 patients with a diagnosis of vaginismus in 2022. Married less than 1 year as many as 6 people (10%), 1-5 years as many as 49 people (82%), and more than 5 years as many as 5 people (8%). Management is carried out independently and collaboratively. The management is independent dilatation with the help of dilators, Botox injection, hymenectomy, and collaboration with psychiatrists and andrologists. Of the 60 patients who underwent anamnesis and physical examination, five patients successfully obtained pregnancy treated with Botox injections, independent dilatation or independent dilatation, and andrology consultation. Proper management of vaginismus can increase the chances of pregnancy.
General surgery
Fatemeh Amirkhanloo; Sedigheh Esmaelzadeh; Mahsima Adnani; Fatemeh Shafizadeh
Volume 7, Issue 6 , September and October 2022, , Pages 578-582
Abstract
Isolated fallopian tube torsion is a rare situation in reproductive-aged women. The gold standard for diagnosis is laparoscopic evaluation, and the treatment of choice is salpingectomy without oophorectomy to preserve fertility. Still, inpatient with a presentation of the acute abdomen or hemodynamically ...
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Isolated fallopian tube torsion is a rare situation in reproductive-aged women. The gold standard for diagnosis is laparoscopic evaluation, and the treatment of choice is salpingectomy without oophorectomy to preserve fertility. Still, inpatient with a presentation of the acute abdomen or hemodynamically unstable, urgent laparotomy is the treatment of choice. Here, we reported a 15-year-old virgin girl presented with acute abdominal pain and evidence of adnexal torsion on the abdominal ultrasonography. Urgent laparotomy revealed an isolated right fallopian tube torsion. Due to irreversible necrosis of the tube, right salpingectomy was performed. It's crucial to consider isolated fallopian tube torsion as a potential cause of abdominal pain in reproductive-aged women and use appropriate diagnostic measures to diagnose it early and preserve their future fertility.
Sara Masihi; Elahe Shirazi; Farideh Moramezi; Najmieh Saadati; Mojgan Barati
Articles in Press, Accepted Manuscript, Available Online from 14 November 2022
Abstract
AbstractPurpose: This study aimed to compare CGH array and karyotype for prenatal diagnosis in high-risk individuals in the first trimester screening.Materials and Methods: The present cross-sectional descriptive prospective study was performed on high-risk mothers screened in the first trimester of ...
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AbstractPurpose: This study aimed to compare CGH array and karyotype for prenatal diagnosis in high-risk individuals in the first trimester screening.Materials and Methods: The present cross-sectional descriptive prospective study was performed on high-risk mothers screened in the first trimester of pregnancy. Individuals were allocated into two groups under karyotype and CGH array. Because this study is based on genetic testing data, it does not require a follow-up. Information on age, number of pregnancies, history of abortion, history of disease and screening results were collected and analyzed. Data analysis was done using SPSS Version 22 (IBM).Results: In total 247 cases were analyzed with 128 cases in the karyotype group and 119 cases in the CGH group. 116 samples (90.6%) in the karyotype group and 99 samples (83.2%) in the CGH group showed a normal karyotype. 4.2% (5 samples) and 7.9% (10 samples) of chromosomal abnormalities were trisomy in the CGH group and the karyotype group, respectively. CGH array analysis on chromosomal abnormalities identified copy number variation (CNV) in about 9.2% (11 samples) of cases. In terms of risk factors structural chromosomal, there was a statistically significant relationship in terms of history of disabled children in the family, maternal age, history of anomalies, screening of the first trimester of pregnancy, and increased NT (p<0.05).Conclusions: High-resolution arrays specifically prevented fetal malformations. Until now, normal prenatal chromosome analysis has been shown a relatively standard method but CGH may be helpful to specialists in diagnosing chromosomal abnormalities, especially in unknown chromosomal abnormalities.
Obstetrics and Gynecology
Arian Karimi Rouzbahani; Nazanin Zarrinkoub; Golnaz Mahmoudvand; Fatemeh Yari
Volume 9, Issue 1 , January and February 2024, , Pages 110-113
Abstract
Single umbilical artery (SUA) is an uncommon yet clinically noticeable anomaly that has been suspected to be correlated with a wide range of pregnancy complications. We hereby present a 30-year-old pregnant woman who was diagnosed with SUA fetus in the 20th week of her pregnancy and was admitted to our ...
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Single umbilical artery (SUA) is an uncommon yet clinically noticeable anomaly that has been suspected to be correlated with a wide range of pregnancy complications. We hereby present a 30-year-old pregnant woman who was diagnosed with SUA fetus in the 20th week of her pregnancy and was admitted to our center in the 33rd week. During the hospitalization, Doppler studies were performed to monitor fetal development. Later, fetoplacental insufficiency and brain-sparing effect were reported on Doppler ultrasound, indicating asymmetrical Intrauterine growth restriction (IUGR). SUA might be associated with concurrent fetal anomalies including cardiological, nephrological, gastrointestinal, and nervous disorders. Moreover, there is an increased risk of small for gestational age and IUGR compared with normal pregnancies. It is crucial to assess the umbilical cord anatomy during pregnancy to diagnose SUA at lower gestational ages and schedule a precise follow-up to prevent adverse outcomes.
Obstetrics and Gynecology
Putri Aini Daulay; Sarah Dina; Soekimin Soekimin
Volume 9, Issue 2 , March and April 2024, , Pages 235-239
Abstract
Endometrial cancer is the 6th most common cancer in women worldwide. Rarely does occur in the postpartum period. Fifteen cases of endometrial cancer in the postpartum period have been reported before, but the diagnosis of endometrial carcinoma as a cause of secondary postpartum hemorrhage is hardly predicted. ...
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Endometrial cancer is the 6th most common cancer in women worldwide. Rarely does occur in the postpartum period. Fifteen cases of endometrial cancer in the postpartum period have been reported before, but the diagnosis of endometrial carcinoma as a cause of secondary postpartum hemorrhage is hardly predicted. A 37-year-old, Para 4, presented two weeks after a cesarean section and had recurrent vaginal bleeding. The patient was treated conservatively. While being observed, vaginal bleeding still occurred with more volume. We decided to perform a total abdominal hysterectomy. Histopathology confirmed a low-grade endometrioid carcinoma of the corpus uteri. Endometrial cancer might cause a secondary postpartum hemorrhage, with the hypothesis that the depth of tumor invasion into the uterine muscle causes a distorted tissue architecture and the formation of new blood vessels that easily disrupt. The most common type of endometrial cancer in a postpartum woman is low grade with a favorable prognosis.
Gynecology Oncology
Fariba Behnamfar; Maryam Nazemi; Fereshteh Mohammadizadeh
Volume 7, Issue 3 , January and February 2022, , Pages 247-250
Abstract
Rhabdomyosarcoma (RMS) is a rare type of sarcoma. Botryoid type is the most common. The peak incidence is the second decade. Cervical RMS is rare in adults. We reported two cases, A, 31 years old woman G1L1 referred to a gynecologist oncologist with abnormal vaginal bleeding. And pathology reported RMS. ...
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Rhabdomyosarcoma (RMS) is a rare type of sarcoma. Botryoid type is the most common. The peak incidence is the second decade. Cervical RMS is rare in adults. We reported two cases, A, 31 years old woman G1L1 referred to a gynecologist oncologist with abnormal vaginal bleeding. And pathology reported RMS. She received 8courses of VAC regimen for chemotherapy .3 weeks after the last course, she underwent conization, and a remnant of sarcoma was seen. A hysterectomy was done for her. She has been disease free for 12 month. Case 2 was a 25 years old nulliparous woman presenting with abnormal vaginal bleeding, vaginal discharge, and cervical polypoid grape like lesion. Pathology reported RMS. Conization was done. Chemotherapy with VAC regimen was done for 8 courses. She has been disease free after 9 years. These two cases showed that RMS can occur in rare places and older ages.
Gynecology Oncology
Tahereh Ashraf Ganjoei; Maryam Talayeh; Noushin Afsharmoghadam; Ali Reza Norouzi; Somayyeh Noei Teymoordash
Volume 7, Issue 6 , September and October 2022, , Pages 583-586
Abstract
Paratubal cysts account for 5-20% of all adnexal lesions. Malignant modifications seldom arise in the paratubal cysts that are usually known as primary carcinomas of fallopian tube. Paratubal borderline tumors are very infrequent conditions and until now only sixteen cases of primary paratubal borderline ...
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Paratubal cysts account for 5-20% of all adnexal lesions. Malignant modifications seldom arise in the paratubal cysts that are usually known as primary carcinomas of fallopian tube. Paratubal borderline tumors are very infrequent conditions and until now only sixteen cases of primary paratubal borderline tumors have been previously reported in the literature. Herein, we describe a rare paratubal serous borderline tumor occurring in a woman of reproductive age and provide insights into its management. A 32-year-old woman referred to Imam Hussein Hospital, Tehran with chief complaint of amenorrhea for the last year and transvaginal sonography (TVS) report indicating a 68×74 mm persistent right adnexal cyst from 10 months ago. The patient was candidate for laparotomy and due to the report of paratubal serous borderline tumor in frozen section she underwent right total salpingectomy and infracolic omentectomy. No evidence of recurrence or metastasis was observed after 3 years of follow up. Persistent adnexal cysts need to be evaluated precisely even in young women in order to rule out the malignancy of fallopian tubes.
Hamideh Parsapour; Aida Alizamir; Shahedeh Khansary; Nasrin Jiryaei; Fatemeh Navabi
Articles in Press, Accepted Manuscript, Available Online from 14 November 2022
Abstract
Background: Gonorrhea is an infection caused by Neisseria gonorrhoeae that is mainly transmitted through sexual intercourse. This study was performed to evaluate the frequency of Neisseria gonorrhoeae and antibiotic resistance pattern to this infection in women referred to Fatemieh Gynecology Clinic ...
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Background: Gonorrhea is an infection caused by Neisseria gonorrhoeae that is mainly transmitted through sexual intercourse. This study was performed to evaluate the frequency of Neisseria gonorrhoeae and antibiotic resistance pattern to this infection in women referred to Fatemieh Gynecology Clinic in Hamadan.Methods: In this cross-sectional study using the convenience sampling method, 348 women referred to the gynecology clinic of Fatemieh Hospital in Hamadan in 2020 with complaints of vaginal discharge or vague pelvic pain were investigated. Patients were examined by a gynecologist, and if were eligible, a sample of endocervix is prepared and sent to the laboratory. Samples were cultured in a Thayer –Martin agar, then were examined by a cytopathologist for Neisseriagnore and Chlamydia and the results were recorded in a researcher-made checklist. Data were analyzed using SPSS software version 16.Results: The mean age of women was 34.93 ±7.57 years, and 72.7% lived in urban areas. Common complaints of women included pelvic inflammatory disease (56.9%), cervical discharge (73.6%), dysuria (25.6%), and dyspareunia (22.7%). None of the women had multiple sexual partners, hepatitis B or hepatitis C. one case (0.29%) of Neisseria gonorrhoeae was observed that be resistant to the antibiotics penicillin tetracycline, minocycline, and cefazolin and was sensitive to the antibiotics chloramphenicol, rifampin, nitrosamine, cefoxitin, and ceftazidime.Conclusion: It seems that in women with cervicitis at reproductive age, without a history of high-risk sexual behaviors, Neisseria gonorrhoeae infection is less common and is not a significant problem.
Gynecology Oncology
Shahrzad Sheikhhasani; Hanna Saffar; Narges Zamani; Mohades Peydayesh; Somayeh Nikfar; Mona Mohseni
Volume 7, Issue 3 , January and February 2022, , Pages 251-253
Abstract
Due to its rarity, the standard clinical presentation, treatment protocol, and prognosis of primitive neuroectodermal tumor (PNET) have not been clearly described yet. Hence, herein we reported a case of ovarian peripheral PNET whose histomorphology reports caused her certain diagnoses at Imam Khomeini ...
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Due to its rarity, the standard clinical presentation, treatment protocol, and prognosis of primitive neuroectodermal tumor (PNET) have not been clearly described yet. Hence, herein we reported a case of ovarian peripheral PNET whose histomorphology reports caused her certain diagnoses at Imam Khomeini Hospital, affiliated to Tehran University of Medical Sciences, Tehran, Iran, in 2020.Considering different clinical presentations, and poor prognosis of PNET compared to other ovarian malignancies, to on-time diagnosis and treatment, the patient's histomorphology and immunohistochemical (IHC) profile assessment, particularly in younger women, seems beneficial.
Obstetrics and Gynecology
Behnaz Moradi; Sara Naybandi Atashi; Elham Shirali
Volume 7, Issue 6 , September and October 2022, , Pages 587-588
Abstract
Adnexal masses characterization is a really challenging issue and is essential for appropriate patient management. Ovarian Adnexal Reporting and Data System (O-RADS) is tone excellent standardized lexicons to provide practical uniform terms, definitions and measurements for describing and classifying ...
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Adnexal masses characterization is a really challenging issue and is essential for appropriate patient management. Ovarian Adnexal Reporting and Data System (O-RADS) is tone excellent standardized lexicons to provide practical uniform terms, definitions and measurements for describing and classifying ovarian masses.In the first publication of O-RADS system, they noted that cystic lesions with maximum diameter of solid component of ≥7 mm, are at higher risk for malignancy. On the other hand, the number of papillary projections had nearly similar positive LR (2.2). Despite this and inclusion of the number of papillary projections in the final risk stratification system, the maximal size of solid part was not included and no cystic lesion with solid component could be categorized in O-RADS 3 category, and size of papillary projection make no change in malignancy risk stratification.In conclusion, we propose that in O-RADS lexicon the use of maximal diameter of solid components (with 7 mm cut off point) along with number of papillary projections is helpful to categorize cystic ovarian mass lesions as auxiliary item for classifying risk of malignancy less than 10% to higher than 50% (O-RADS 3 to ORADS 5).
Hamideh Pakniat; Khadijeh Elmizadeh; Fatemeh Lalouha; Hojjat Momenzade; Kimia Mahloojian
Articles in Press, Accepted Manuscript, Available Online from 14 November 2022
Abstract
Background & Objective: The importance of Pap smear in cervical cancer screening is clear. However, yet no organized program has been developed in Iran to screen cervical cancer. Due to the obvious difference in prevalence of cervical cancer in Iran compared to global statistics, it is necessary ...
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Background & Objective: The importance of Pap smear in cervical cancer screening is clear. However, yet no organized program has been developed in Iran to screen cervical cancer. Due to the obvious difference in prevalence of cervical cancer in Iran compared to global statistics, it is necessary to further investigate this issue. As pop smear is the most important factor to decrease the mortality and morbidity of cervical cancer in developed countries, it is important to study the results of abnormal Pap smears and the quality of the report in our region. Materials & Methods: This study was designed retrospectively with reference to the results of Pap smears performed during 3 years from 2016 in the Kosar hospital. The method of collecting samples was census. The results of Pap smears were extracted from the Hospital and 15208 pap smear results were analyzed.Results: From the 15208 women, 15150 had normal cytology results (99.62%) and 58 women had abnormal cytology (0.38%). The frequency of abnormal cytology was 0.246% (n=37) for atypical squamous cell of undetermined significance (ASCUS), 0.08% (n=12) for low-grade squamous intraepithelial lesion (LSIL), 0.006% (n=1)for ASC cannot exclude high-grade intraepithelial lesion (ASC-H), 0.046% (n=7) for high-grade squamous intraepithelial lesion(HSIL), 0.006 (n=1)for atypical glandular cells (AGC), and 0% (n=0) for invasive cancer. No SCC was found in this study. Conclusion: The prevalence of all abnormal results was much lower than other studies; However, in terms of prevalence of abnormalities, the ranking was similar to other studies.In order to obtain more accurate results, it is recommended to study other epidemiological regions.
Maternal Fetal Medicine
Marjan Ahmadi; Seyed Mohammad Ayyoubzadeh; Sakineh Abbasi
Volume 7, Issue 3 , January and February 2022, , Pages 254-255
Abstract
Pregnant women are at higher risk of severe COVID-19 than the general population. Furthermore, COVID-19 increases the preterm and cesarean rates due to maternal and fetal complications. Owing to the adverse effects of the COVID-19 on pregnant women, in-person prenatal visits face challenges. Thus, alternative ...
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Pregnant women are at higher risk of severe COVID-19 than the general population. Furthermore, COVID-19 increases the preterm and cesarean rates due to maternal and fetal complications. Owing to the adverse effects of the COVID-19 on pregnant women, in-person prenatal visits face challenges. Thus, alternative solutions that reduce the number of visits while preserving maternal and fetal care quality should be considered. Digital health is one of the potential solutions. Obstetricians and gynecologists, and other clinical experts should cooperate to define digital tools’ requirements and standards for prenatal care. Moreover, governments and healthcare insurances should facilitate the coverage of provided services’ costs by digital health tools, especially in developing countries.
Marzieh Talebian; Zohreh Talebi Mazreshahi; Elham Khosravi Mashizi; Nafiseh Khalili
Articles in Press, Accepted Manuscript, Available Online from 14 November 2022
Abstract
Introduction: Although 1% to 2% of all pregnancies are ectopic, ectopic pregnancy (EP) is the most frequent obstetrical disease leads to maternal mortality and morbidity at first trimester. The basic diagnostic method of EP is the human chorionic gonadotropin (HCG) test and transvaginal ultrasound. There ...
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Introduction: Although 1% to 2% of all pregnancies are ectopic, ectopic pregnancy (EP) is the most frequent obstetrical disease leads to maternal mortality and morbidity at first trimester. The basic diagnostic method of EP is the human chorionic gonadotropin (HCG) test and transvaginal ultrasound. There are some rare EP cases with negative HCG blood test. Case presentation: A 31-years old woman referred to the emergency department with hypogastric, periumbilical, and right upper quadrant intermittent pain and vaginal bleeding and prior history of EP 7-months ago that treated with methotrexate and her intra uterine device had been removed at that time. Her last menstrual period was undetermined. Although HCG blood test-qualitative was negative (2.08 IU /ml),ultrasound examination showed an 43×53 mm echogenic, heterogenic complex solid mass in the left adnexa and a large amount of echogenic fluid demonstrating hemoperitoneum. Taken surgery because of the exceeded abdominal pain revealed active bleeding in the left salpinx due to ruptured EP. Conclusion: Management of patients suspected of EP with negative HCG-blood test is difficult. In this uncommon cases in emergency, computed tomography, ultrasound and diagnostic laparoscopy or laparotomy can improve prognosis of patient.
